What does CUSIP 462222100 represent in this 13F holders report?

CUSIP 462222100 is the security identifier for IONS - IONIS PHARMACEUTICALS INC - Common Stock used to aggregate holder disclosures.

How many institutions held IONS - IONIS PHARMACEUTICALS INC - Common Stock in Q2 2022?

329 institutional investors reported IONS - IONIS PHARMACEUTICALS INC - Common Stock for Q2 2022. Use the holders table for investor-level position and value details.

IONIS PHARMACEUTICALS INC - Common Stock (IONS)

CUSIP: 462222100

Q2 2022 13F Holders as of 30 Jun 2022

Type / Class: Equity / Common Stock
Shares outstanding: 162,643,196
Total 13F shares: 124,531,298
Share change: +168,581
Total reported value: $4,607,099,903
Put/Call ratio: 32%
Price per share: $37.02
Number of holders: 329
Value change: +$7,650,768
Number of buys: 136
Number of sells: 153

Quarterly Holders Quick Answers

What is CUSIP 462222100?
CUSIP 462222100 identifies IONS - IONIS PHARMACEUTICALS INC - Common Stock in SEC institutional holdings data.

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Explore More Reporting Periods

Jump to adjacent filing periods for faster comparison and easier crawl discovery.

Newer quarter: Q3 2022
Previous quarter: Q1 2022

Recent filing periods for CUSIP 462222100:

Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024

Top shareholders of IONS - IONIS PHARMACEUTICALS INC - Common Stock (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
FMR LLC	13F	Company	13%	21,320,885	$789,725,000	—	31 Mar 2022	13F
PRICE T ROWE ASSOCIATES INC /MD/	13F	Company	8.8%	14,350,460	$531,541,000	—	31 Mar 2022	13F
VANGUARD GROUP INC	13F	Company	7.4%	12,099,034	$448,148,000	—	31 Mar 2022	13F
Bellevue Group AG	13F	Company	6.1%	9,918,073	$367,365,000	—	31 Mar 2022	13F
BlackRock Finance, Inc.	13F	Company	5.2%	8,443,843	$312,761,000	—	31 Mar 2022	13F
Clearbridge Investments, LLC	13F	Company	4%	6,476,033	$239,872,000	—	31 Mar 2022	13F
ARK Investment Management LLC	13F	Company	3.8%	6,171,308	$228,585,000	—	31 Mar 2022	13F
STATE STREET CORP	13F	Company	2.5%	4,030,646	$149,295,000	—	31 Mar 2022	13F
Camber Capital Management LP	13F	Company	1.8%	3,000,000	$111,120,000	—	31 Mar 2022	13F
Tweedy, Browne Co LLC	13F	Company	1.8%	2,925,102	$108,346,000	—	31 Mar 2022	13F
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	1.2%	1,897,492	$70,283,000	—	31 Mar 2022	13F
JACOBS LEVY EQUITY MANAGEMENT, INC	13F	Company	0.99%	1,618,267	$59,941,000	—	31 Mar 2022	13F
FIRST TRUST ADVISORS LP	13F	Company	0.99%	1,616,290	$59,867,000	—	31 Mar 2022	13F
THRIVENT FINANCIAL FOR LUTHERANS	13F	Company	0.96%	1,561,513	$57,839,000	—	31 Mar 2022	13F
CITADEL ADVISORS LLC	13F	Company	0.77%	1,244,524	$46,098,000	—	31 Mar 2022	13F
JPMORGAN CHASE & CO	13F	Company	0.73%	1,181,557	$43,765,000	—	31 Mar 2022	13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	13F	Company	0.7%	1,137,827	$42,145,000	—	31 Mar 2022	13F
Swedbank AB	13F	Company	0.69%	1,117,339	$41,386,237	—	31 Mar 2022	13F
GOLDMAN SACHS GROUP INC	13F	Company	0.59%	954,326	$35,348,000	—	31 Mar 2022	13F
WELLS FARGO & COMPANY/MN	13F	Company	0.52%	842,284	$31,198,000	—	31 Mar 2022	13F
TD ASSET MANAGEMENT INC	13F	Company	0.5%	820,164	$30,379,000	—	31 Mar 2022	13F
NORGES BANK	13F	Company	0.48%	785,561	$29,097,179	—	31 Mar 2022	13F
TWO SIGMA INVESTMENTS, LP	13F	Company	0.48%	780,256	$28,901,000	—	31 Mar 2022	13F
BANK OF AMERICA CORP /DE/	13F	Company	0.47%	762,158	$28,230,000	—	31 Mar 2022	13F
NORTHERN TRUST CORP	13F	Company	0.4%	648,534	$24,020,000	—	31 Mar 2022	13F
TWO SIGMA ADVISERS, LP	13F	Company	0.38%	611,611	$22,654,000	—	31 Mar 2022	13F
Sumitomo Mitsui Trust Group, Inc.	13F	Company	0.37%	599,616	$22,210,000	—	31 Mar 2022	13F
Amova Asset Management Americas, Inc.	13F	Company	0.37%	599,616	$21,490,000	—	31 Mar 2022	13F
Bank of New York Mellon Corp	13F	Company	0.34%	549,246	$20,346,000	—	31 Mar 2022	13F
PINNACLE ASSOCIATES LTD	13F	Company	0.32%	521,968	$19,334,000	—	31 Mar 2022	13F
MORGAN STANLEY	13F	Company	0.32%	519,477	$19,241,000	—	31 Mar 2022	13F
S.c.a. Candriam	13F	Individual	0.31%	499,547	$18,502,000	—	31 Mar 2022	13F
ROYAL BANK OF CANADA	13F	Company	0.27%	444,502	$16,464,000	—	31 Mar 2022	13F
NOMURA HOLDINGS INC	13F	Company	0.24%	394,154	$15,330,000	—	31 Mar 2022	13F
Assenagon Asset Management S.A.	13F	Company	0.22%	357,896	$13,256,000	—	31 Mar 2022	13F
DIMENSIONAL FUND ADVISORS LP	13F	Company	0.22%	353,481	$13,089,000	—	31 Mar 2022	13F
BAILLIE GIFFORD & CO	13F	Company	0.21%	348,863	$12,922,000	—	31 Mar 2022	13F
STIFEL FINANCIAL CORP	13F	Company	0.21%	340,566	$12,615,000	—	31 Mar 2022	13F
BARCLAYS PLC	13F	Company	0.19%	316,350	$11,717,000	—	31 Mar 2022	13F
Sicart Associates LLC	13F	Company	0.19%	304,782	$11,289,000	—	31 Mar 2022	13F
DOWLING & YAHNKE LLC	13F	Company	0.19%	302,571	$11,207,000	—	31 Mar 2022	13F
Swiss National Bank	13F	Company	0.18%	300,500	$11,131,000	—	31 Mar 2022	13F
Nuveen Asset Management, LLC	13F	Company	0.19%	315,819	$11,028,000	—	31 Mar 2022	13F
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM	13F	Company	0.18%	294,815	$10,920,000	—	31 Mar 2022	13F
Russell Investments Group, Ltd.	13F	Company	0.17%	284,130	$10,521,000	—	31 Mar 2022	13F
BANK OF MONTREAL /CAN/	13F	Company	0.17%	268,497	$9,583,000	—	31 Mar 2022	13F
RAYMOND JAMES & ASSOCIATES	13F	Company	0.16%	256,726	$9,509,000	—	31 Mar 2022	13F
PARAMETRIC PORTFOLIO ASSOCIATES LLC	13F	Company	0.14%	230,804	$8,549,000	—	31 Mar 2022	13F
Morningstar Investment Services LLC	13F	Company	0.14%	222,681	$7,996,000	—	31 Mar 2022	13F
Hudson Bay Capital Management LP	13F	Company	0.13%	210,000	$7,778,000	—	31 Mar 2022	13F

Institutional Holders of IONIS PHARMACEUTICALS INC - Common Stock (IONS) as of Q2 2022

As of 30 Jun 2022, IONIS PHARMACEUTICALS INC - Common Stock (IONS) was held by 329 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 124,531,298 shares. The largest 10 holders included FMR LLC, PRICE T ROWE ASSOCIATES INC /MD/, VANGUARD GROUP INC, Bellevue Group AG, BlackRock Inc., Clearbridge Investments, LLC, ARK Investment Management LLC, STATE STREET CORP, Tweedy, Browne Co LLC, and Camber Capital Management LP. This page lists 330 institutional shareholders reporting positions in this security for the Q2 2022 filing period.

Investor	Option	Weight %	Change %	Value $	* Price	Shares	Share Change	Activity	Report Period

Compare Q2 2022 vs Q1 2022 Across Filers

Q1 2022 holders

314

Q2 2022 holders

329

Holder diff

Investor	Q1 2022 Shares	Q2 2022 Shares	Share Diff	Share Chg %	Q1 2022 Value $	Q2 2022 Value $	Value Diff $	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.