What does CUSIP 462222100 represent in this 13F holders report?

CUSIP 462222100 is the security identifier for IONS - IONIS PHARMACEUTICALS INC - Common Stock used to aggregate holder disclosures.

How many institutions held IONS - IONIS PHARMACEUTICALS INC - Common Stock in Q2 2021?

321 institutional investors reported IONS - IONIS PHARMACEUTICALS INC - Common Stock for Q2 2021. Use the holders table for investor-level position and value details.

IONIS PHARMACEUTICALS INC - Common Stock (IONS)

CUSIP: 462222100

Q2 2021 13F Holders as of 30 Jun 2021

Type / Class: Equity / Common Stock
Shares outstanding: 162,643,196
Total 13F shares: 124,355,726
Share change: +2,320,295
Total reported value: $4,958,884,573
Put/Call ratio: 66%
Price per share: $39.89
Number of holders: 321
Value change: +$71,970,644
Number of buys: 157
Number of sells: 170

Quarterly Holders Quick Answers

What is CUSIP 462222100?
CUSIP 462222100 identifies IONS - IONIS PHARMACEUTICALS INC - Common Stock in SEC institutional holdings data.

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Explore More Reporting Periods

Jump to adjacent filing periods for faster comparison and easier crawl discovery.

Newer quarter: Q3 2021
Previous quarter: Q1 2021

Recent filing periods for CUSIP 462222100:

Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024

Top shareholders of IONS - IONIS PHARMACEUTICALS INC - Common Stock (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
FMR LLC	13F	Company	13%	21,093,896	$948,382,000	—	31 Mar 2021	13F
VANGUARD GROUP INC	13F	Company	7.7%	12,604,149	$566,682,000	—	31 Mar 2021	13F
PRICE T ROWE ASSOCIATES INC /MD/	13F	Company	7.7%	12,580,056	$565,599,000	—	31 Mar 2021	13F
BlackRock Finance, Inc.	13F	Company	6%	9,808,562	$440,995,000	—	31 Mar 2021	13F
Bellevue Group AG	13F	Company	5.5%	8,984,234	$403,932,000	—	31 Mar 2021	13F
Clearbridge Investments, LLC	13F	Company	4.6%	7,402,967	$332,837,000	—	31 Mar 2021	13F
ARK Investment Management LLC	13F	Company	3.2%	5,142,271	$231,197,000	—	31 Mar 2021	13F
STATE STREET CORP	13F	Company	2.1%	3,409,571	$153,294,000	—	31 Mar 2021	13F
Invesco Ltd.	13F	Company	1.5%	2,359,434	$106,080,000	—	31 Mar 2021	13F
JPMORGAN CHASE & CO	13F	Company	1.2%	1,963,223	$88,266,000	—	31 Mar 2021	13F
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	1.1%	1,729,146	$77,645,000	—	31 Mar 2021	13F
WADDELL & REED FINANCIAL INC	13F	Company	0.99%	1,613,947	$72,563,000	—	31 Mar 2021	13F
BVF INC/IL	13F	Company	0.84%	1,364,461	$61,346,000	—	31 Mar 2021	13F
FIRST TRUST ADVISORS LP	13F	Company	0.72%	1,167,809	$52,505,000	—	31 Mar 2021	13F
WELLS FARGO & COMPANY/MN	13F	Company	0.71%	1,156,999	$52,018,000	—	31 Mar 2021	13F
Swedbank AB	13F	Company	0.69%	1,121,067	$50,403,171	—	31 Mar 2021	13F
Camber Capital Management LP	13F	Company	0.61%	1,000,000	$44,960,000	—	31 Mar 2021	13F
Nuveen Asset Management, LLC	13F	Company	0.58%	949,237	$42,678,000	—	31 Mar 2021	13F
AMERICAN CENTURY COMPANIES INC	13F	Company	0.58%	942,678	$42,383,000	—	31 Mar 2021	13F
Sumitomo Mitsui Trust Group, Inc.	13F	Company	0.55%	901,301	$40,522,000	—	31 Mar 2021	13F
NORTHERN TRUST CORP	13F	Company	0.52%	841,145	$37,818,000	—	31 Mar 2021	13F
NORGES BANK	13F	Company	0.5%	807,488	$36,305,000	—	31 Mar 2021	13F
GOLDMAN SACHS GROUP INC	13F	Company	0.46%	744,910	$33,491,000	—	31 Mar 2021	13F
Rockefeller Capital Management L.P.	13F	Company	0.45%	733,979	$32,998,000	—	31 Mar 2021	13F
TWO SIGMA ADVISERS, LP	13F	Company	0.44%	714,411	$32,120,000	—	31 Mar 2021	13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	13F	Company	0.43%	696,496	$31,315,000	—	31 Mar 2021	13F
BANK OF AMERICA CORP /DE/	13F	Company	0.43%	691,583	$31,092,000	—	31 Mar 2021	13F
MILLENNIUM MANAGEMENT LLC	13F	Company	0.39%	631,264	$28,382,000	—	31 Mar 2021	13F
FARALLON CAPITAL MANAGEMENT LLC	13F	Company	0.39%	630,500	$28,347,000	—	31 Mar 2021	13F
RENAISSANCE TECHNOLOGIES LLC	13F	Company	0.36%	587,414	$26,410,000	—	31 Mar 2021	13F
MORGAN STANLEY	13F	Company	0.35%	567,667	$25,522,000	—	31 Mar 2021	13F
Bank of New York Mellon Corp	13F	Company	0.34%	545,098	$24,507,000	—	31 Mar 2021	13F
PINNACLE ASSOCIATES LTD	13F	Company	0.32%	513,124	$23,070,000	—	31 Mar 2021	13F
Swiss National Bank	13F	Company	0.31%	510,359	$22,946,000	—	31 Mar 2021	13F
Amova Asset Management Americas, Inc.	13F	Company	0.31%	498,256	$22,402,000	—	31 Mar 2021	13F
Woodline Partners LP	13F	Company	0.29%	475,891	$21,396,000	—	31 Mar 2021	13F
DIMENSIONAL FUND ADVISORS LP	13F	Company	0.28%	457,281	$20,563,000	—	31 Mar 2021	13F
Gamma As Sector	13F	Individual	0.28%	454,150	$20,419,000	—	31 Mar 2021	13F
ALTRINSIC GLOBAL ADVISORS LLC	13F	Company	0.27%	441,054	$19,830,000	—	31 Mar 2021	13F
Alyeska Investment Group, L.P.	13F	Company	0.26%	427,990	$19,242,000	—	31 Mar 2021	13F
TD ASSET MANAGEMENT INC	13F	Company	0.26%	424,579	$19,089,000	—	31 Mar 2021	13F
Legal & General Group Plc	13F	Company	0.26%	420,377	$18,900,000	—	31 Mar 2021	13F
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC	13F	Company	0.25%	404,524	$18,187,398	—	31 Mar 2021	13F
STIFEL FINANCIAL CORP	13F	Company	0.23%	380,398	$17,103,000	—	31 Mar 2021	13F
FIRST MANHATTAN CO. LLC.	13F	Company	0.23%	375,300	$16,873,000	—	31 Mar 2021	13F
Sicart Associates LLC	13F	Company	0.23%	370,298	$16,649,000	—	31 Mar 2021	13F
INTERNATIONAL BIOTECHNOLOGY TRUST PLC	13F	Company	0.21%	333,781	$15,003,000	—	31 Mar 2021	13F
Verition Fund Management LLC	13F	Company	0.2%	319,539	$14,366,000	—	31 Mar 2021	13F
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM	13F	Company	0.19%	316,577	$14,233,000	—	31 Mar 2021	13F
BANK OF MONTREAL /CAN/	13F	Company	0.2%	322,230	$13,755,000	—	31 Mar 2021	13F

Institutional Holders of IONIS PHARMACEUTICALS INC - Common Stock (IONS) as of Q2 2021

As of 30 Jun 2021, IONIS PHARMACEUTICALS INC - Common Stock (IONS) was held by 321 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 124,355,726 shares. The largest 10 holders included FMR LLC, VANGUARD GROUP INC, PRICE T ROWE ASSOCIATES INC /MD/, Bellevue Group AG, ARK Investment Management LLC, BlackRock Inc., Clearbridge Investments, LLC, STATE STREET CORP, JPMORGAN CHASE & CO, and Camber Capital Management LP. This page lists 322 institutional shareholders reporting positions in this security for the Q2 2021 filing period.

Investor	Option	Weight %	Change %	Value $	* Price	Shares	Share Change	Activity	Report Period

Compare Q2 2021 vs Q1 2021 Across Filers

Q1 2021 holders

347

Q2 2021 holders

321

Holder diff

-26

Investor	Q1 2021 Shares	Q2 2021 Shares	Share Diff	Share Chg %	Q1 2021 Value $	Q2 2021 Value $	Value Diff $	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.