| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Two Seas Capital LP | 4.7% | -6% | $25,836,769 | -$543,915 | 9,749,724 | -2.1% | Two Seas Capital LP | 30 Sep 2025 |
| BB BIOTECH AG | 4.9% | -2% | $8,821,598 | -$227,500 | 9,694,064 | -2.5% | BB Biotech AG | 04 Mar 2025 |
| WASATCH ADVISORS LP | 3.5% | -33.3% | $18,713,921 | -$10,253,910 | 7,061,857 | -35.4% | Wasatch Advisors LP | 30 Sep 2025 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Change | Price | Investors |
|---|---|---|---|---|---|
| 2025 Q3 | 108,004,285 | $286,206,908 | +$32,005,545 | $2.65 | 188 |
| 2025 Q2 | 98,221,986 | $96,659,560 | -$21,194,525 | $0.9844 | 161 |
| 2025 Q1 | 111,244,473 | $160,207,390 | -$24,300,645 | $1.44 | 183 |
| 2024 Q4 | 126,046,299 | $277,285,420 | +$4,393,183 | $2.2 | 188 |
| 2024 Q3 | 128,986,677 | $212,839,069 | -$18,982,245 | $1.65 | 181 |
| 2024 Q2 | 136,753,565 | $303,582,298 | +$17,706,459 | $2.22 | 173 |
| 2024 Q1 | 125,253,343 | $335,669,495 | +$141,351,114 | $2.68 | 147 |
| 2023 Q4 | 71,634,221 | $214,185,830 | -$13,154,422 | $2.99 | 127 |
| 2023 Q3 | 77,232,361 | $75,678,982 | -$1,733,880 | $0.98 | 120 |
| 2023 Q2 | 74,286,796 | $103,280,736 | -$10,483,186 | $1.39 | 121 |
| 2023 Q1 | 80,929,285 | $128,750,548 | -$22,081,506 | $1.59 | 161 |
| 2022 Q4 | 73,478,005 | $457,748,937 | +$39,215,603 | $6.23 | 164 |
| 2022 Q3 | 62,444,882 | $418,381,560 | +$53,328,619 | $6.7 | 143 |
| 2022 Q2 | 55,366,705 | $352,132,262 | +$24,287,037 | $6.36 | 128 |
| 2022 Q1 | 51,922,058 | $241,219,302 | -$10,656,706 | $4.64 | 121 |
| 2021 Q4 | 53,613,124 | $268,022,905 | +$97,310,967 | $5 | 119 |
| 2021 Q3 | 24,797,305 | $298,815,522 | -$61,530,602 | $12.05 | 133 |
| 2021 Q2 | 28,340,478 | $599,385,890 | -$18,947,335 | $21.15 | 140 |
| 2021 Q1 | 28,702,213 | $805,059,737 | -$64,474,348 | $28.05 | 151 |
| 2020 Q4 | 30,878,165 | $802,895,778 | -$34,208,444 | $26 | 152 |
| 2020 Q3 | 31,640,175 | $1,176,015,102 | -$28,756,691 | $37.17 | 165 |
| 2020 Q2 | 31,971,491 | $1,640,380,010 | +$123,898,647 | $51.31 | 179 |
| 2020 Q1 | 29,570,957 | $916,082,618 | +$53,953,340 | $31.53 | 157 |
| 2019 Q4 | 27,848,044 | $1,621,473,992 | +$45,891,970 | $59.63 | 170 |
| 2019 Q3 | 27,027,940 | $990,522,973 | -$72,172,854 | $36.66 | 145 |
| 2019 Q2 | 28,447,747 | $1,323,221,426 | +$216,701,139 | $46.52 | 166 |
| 2019 Q1 | 27,588,882 | $1,107,641,121 | +$27,039,632 | $40.15 | 160 |
| 2018 Q4 | 26,812,324 | $1,233,297,022 | -$65,824,574 | $46 | 152 |
| 2018 Q3 | 28,254,155 | $1,253,898,089 | -$106,658,510 | $44.37 | 151 |
| 2018 Q2 | 30,817,874 | $1,207,760,885 | +$133,006,694 | $39.19 | 151 |
| 2018 Q1 | 26,467,526 | $1,914,388,196 | +$178,186,545 | $72.33 | 184 |
| 2017 Q4 | 24,011,278 | $1,580,908,389 | +$28,478,384 | $65.84 | 163 |
| 2017 Q3 | 24,158,062 | $1,210,838,699 | +$158,389,093 | $50.12 | 150 |
| 2017 Q2 | 20,787,063 | $962,036,441 | +$142,703,625 | $46.28 | 129 |
| 2017 Q1 | 17,982,623 | $634,962,044 | +$201,687,554 | $35.31 | 116 |
| 2016 Q4 | 14,790,757 | $185,178,042 | +$1,997,113 | $12.52 | 96 |
| 2016 Q3 | 14,434,779 | $199,910,330 | -$703,426 | $13.85 | 98 |
| 2016 Q2 | 14,667,103 | $144,916,054 | -$27,764,688 | $9.88 | 98 |
| 2016 Q1 | 15,788,626 | $266,644,000 | -$13,544,152 | $16.91 | 104 |
| 2015 Q4 | 16,427,090 | $365,743,034 | -$11,898,095 | $22.26 | 111 |
| 2015 Q3 | 16,611,937 | $391,855,349 | -$215,978,223 | $23.59 | 120 |
| 2015 Q2 | 15,304,049 | $1,251,247,346 | +$182,794,461 | $81.76 | 150 |
| 2015 Q1 | 12,803,656 | $1,185,461,048 | +$474,650,240 | $92.6 | 139 |
| 2014 Q4 | 7,779,336 | $314,790,098 | +$168,789,584 | $40.44 | 82 |
| 2014 Q3 | 3,501,400 | $85,642,436 | +$3,067,413 | $24.46 | 49 |
| 2014 Q2 | 5,556,294 | $88,004,478 | +$33,701,269 | $15.84 | 43 |
| 2014 Q1 | 3,430,835 | $51,872,345 | +$961,180 | $15.12 | 40 |