Centessa Pharmaceuticals plc - Ordinary Shares, nominal value 0.002 per share (CNTA)

Q: What does CUSIP 152309100 represent in this 13F holders report?

CUSIP 152309100 is the security identifier for CNTA - Centessa Pharmaceuticals plc - Ordinary Shares, nominal value 0.002 per share used to aggregate holder disclosures.

Q: How many institutions held CNTA - Centessa Pharmaceuticals plc - Ordinary Shares, nominal value 0.002 per share in Q4 2025?

148 institutional investors reported CNTA - Centessa Pharmaceuticals plc - Ordinary Shares, nominal value 0.002 per share for Q4 2025. Use the holders table for investor-level position and value details.

CUSIP: 152309100

Q4 2025 13F Holders as of 31 Dec 2025

Security type / class: Equity / Ordinary Shares, nominal value 0.002 per share
Total 13F shares: 143,761,479
Total 13F value: $3,595,362,437
Share change: +15,436,787
Put/Call ratio: 60%
SEC-reported price per share: $25.01
Number of holders: 148
Value change: +$388,868,676
Number of buys: 87
Number of sells: 64
Shares outstanding: 153,608,082

Security key

152309100

Report period

Q4 2025

Institutions

148

Top holders

CNTA full security history Ownership snapshot Full 13F holder table Newer quarter: Q2 2026 Centessa Pharmaceuticals plc SEC filings Centessa Pharmaceuticals plc company facts

Broader feeds

Latest 13F filings Latest 13D/G filings Investors directory

Reporting periods

Holder history for CUSIP 152309100

Newer quarter: Q2 2026

Recent filing periods:

Q2 2026

Ownership snapshot

Top reported holders of CNTA - Centessa Pharmaceuticals plc - Ordinary Shares, nominal value 0.002 per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader

General Atlantic Cooperat...

Disclosed value leader

Medicxi Ventures Manageme...

Comparable rows

15/15

Latest evidence

25 Nov 2025

13D/G 13F Lead comparable stake: 5% 13D/G row: General Atlantic Cooperatief U.A. Showing 1-6 of 15 holder rows.

Quick read

General Atlantic Cooperatief U.A. leads the comparable SEC ownership view at 5%.

15 of 15 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens General Atlantic Cooperatief U.A.'s linked filing trail.

Comparable ownership Top 5

General Atlantic Cooperatief U.A. 5%

Medicxi Ventures Management (Jers... 13%

Avoro Capital Advisors LLC 7%

ADAGE CAPITAL PARTNERS GP, L.L.C. 6.5%

Index Venture Life Associates VI Ltd 6.5%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-6 of 15 holder rows

Holder	Evidence	Ownership %	Position	12M Net Δ	As of
General Atlantic Cooperatief U.A.	13D/G 13D/G	5%	$180,192,368 7,366,818 shares	-$56,624,900	25 Nov 2025
Medicxi Ventures Management (Jersey) Ltd	13F Company 13F	13%	$484,106,557 19,963,157 shares	—	30 Sep 2025
Avoro Capital Advisors LLC	13F Company 13F	7%	$262,095,940 10,808,080 shares	—	30 Sep 2025
ADAGE CAPITAL PARTNERS GP, L.L.C.	13F Company 13F	6.5%	$243,348,750 10,035,000 shares	—	30 Sep 2025
Index Venture Life Associates VI Ltd	13F Company 13F	6.5%	$241,573,383 9,961,789 shares	—	30 Sep 2025
GENERAL ATLANTIC, L.P.	13F Company 13F	6.3%	$234,784,087 9,681,818 shares	—	30 Sep 2025

How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

13F holder rows

Institutional holders as of Q4 2025

Investor-level positions for this CUSIP, loaded as an interactive table.

Institutions

148

143,761,479

Rows available

148

Investor	Option	Weight %	Change %	SEC-reported value	* Price	Shares	Share Change	Activity	Report Period

^* SEC-reported price is the security price as of the portfolio date and can indicate the last known price at which the security was still held. The marker flags a reported price that did not pass the local price check.

Compare Q4 2025 vs Q3 2025 Across Filers

Q3 2025 holders

124

Q4 2025 holders

148

Holder diff

Investor	Q3 2025 Shares	Q4 2025 Shares	Share Diff	Share Chg %	Q3 2025 value	Q4 2025 value	Value change	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend