Security Snapshot

Centessa Pharmaceuticals plc - Ordinary Shares, nominal value GBP 0.002 per share (CNTA) Institutional Ownership

CUSIP: 152309100

13F Institutional Holders and Ownership History from Q2 2021 to Q1 2026

Latest Period

Q1 2026

Institutions Reporting

160

Shares (Excl. Options)

148,632,709

Price

$39.72

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Latest holder snapshot 5 signals
Portfolio coverage rank
0.01%
Share change
+4,874,750
Value change
+$329,840,050
Number of holders
160
Issuer context Names, identifiers, and filing context for this profile. 3 identity fields
Shares outstanding
154,150,943
SEC-reported price per share
$39.58
Insider filing price
$39.58
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors

Key facts

  • CNTA - Centessa Pharmaceuticals plc - Ordinary Shares, nominal value GBP 0.002 per share is tracked under CUSIP 152309100.
  • 160 institutions reported positions in Q1 2026.
  • 5 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 147 to 160 between Q4 2025 and Q1 2026.
  • SEC-reported value moved from $3,595,359,236 to $5,896,478,651.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 160 institutions filings for Q1 2026.

Open SEC evidence

Security key

152309100

Latest holder period

Q1 2026

13F holders

160

13D/G owners

5

CIK / CUSIP context first

13D/G owners

Significant owners

Large-stake holder rows connected to Schedule 13D/G evidence.

Rows
5
Security
CNTA
Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Avoro Capital Advisors LLC 7.4% -26% $452,303,104 -$123,660,207 11,430,455 -21% Avoro Capital Advisors LLC 31 Mar 2026
Adage Capital Management, L.P. 5.8% -24% $353,162,646 -$43,922,304 8,925,010 -11% Adage Capital Management, L.P. 31 Mar 2026
Pentwater Capital Management LP 5.3% $323,286,900 8,170,000 Pentwater Capital Management LP 31 Mar 2026
General Atlantic Cooperatief U.A. 5% -23% $180,192,368 -$56,624,900 7,366,818 -24% General Atlantic Cooperatief U.A. 25 Nov 2025
FMR LLC 7.5% -39% $268,405,170 -$166,856,639 6,783,047 -38% FMR LLC 31 Mar 2026

As of 31 Mar 2026, 160 institutional investors reported holding 148,632,709 shares of Centessa Pharmaceuticals plc - Ordinary Shares, nominal value GBP 0.002 per share (CNTA). This represents 96% of the company’s total 154,150,943 outstanding shares.

13F concentration

Top 25 institutional shareholders

Largest 13F positions for this security by reported shares and value.

Top holder share
80%
Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
Medicxi Ventures Management (Jersey) Ltd 13% 19,963,157 0% 81% $792,936,596
Avoro Capital Advisors LLC 7.4% 11,430,455 -21% 4.5% $454,017,673
Index Venture Life Associates VI Ltd 6.5% 9,961,789 0% 100% $395,682,259
ADAGE CAPITAL PARTNERS GP, L.L.C. 5.8% 8,925,010 -21% 0.55% $354,501,397
Pentwater Capital Management LP 5.3% 8,170,000 2.3% $324,512,400
FMR LLC 4.4% 6,852,047 -24% 0.01% $272,163,307
EcoR1 Capital, LLC 3.9% 6,000,000 +93% 10% $238,320,000
PERCEPTIVE ADVISORS LLC 3.4% 5,258,903 +80% 4.1% $208,883,627
Capital World Investors 3.1% 4,832,548 +317% 0.03% $191,948,807
FARALLON CAPITAL MANAGEMENT LLC 3.1% 4,809,000 -11% 1.2% $191,013,480
TCG Crossover Management, LLC 2.8% 4,286,480 0% 4.9% $170,258,986
MORGAN STANLEY 2.8% 4,268,353 +285% 0.01% $169,538,989
Paradigm Biocapital Advisors LP 2.3% 3,574,048 2.9% $141,961,187
JANUS HENDERSON GROUP PLC 2.3% 3,492,977 -15% 0.07% $138,741,046
Deep Track Capital, LP 2% 3,158,041 +58% 2.6% $125,437,389
Logos Global Management LP 1.4% 2,125,000 +962% 4.3% $84,405,000
RTW INVESTMENTS, LP 1.3% 2,054,175 +15% 0.81% $81,591,831
FEDERATED HERMES, INC. 1.3% 2,049,439 -12% 0.13% $81,403,717
BRAIDWELL LP 1.3% 1,986,768 -9.2% 2.6% $78,914,425
BANK OF AMERICA CORP /DE/ 1.3% 1,932,406 +104% 0.01% $76,755,166
MAVERICK CAPITAL LTD 1.2% 1,854,488 +13% 0.86% $73,660,263
First Light Asset Management, LLC 1% 1,560,991 -32% 5.6% $62,002,563
Affinity Asset Advisors, LLC 0.91% 1,400,000 +133% 3.3% $55,608,000
Foresite Capital Management VI LLC 0.88% 1,364,019 0% 12% $54,178,835
GENERAL ATLANTIC, L.P. 0.88% 1,354,830 -78% 2.5% $53,813,848

Quarter history

Institutional holders across reporting periods

Holder count, reported shares/value, and median price by quarter.

Periods
20
Latest
Q1 2026
Rows shown
1-20 of 20
Period 13F Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q1 148,632,709 $5,896,478,651 +$329,840,050 $39.72 160
2025 Q4 143,761,351 $3,595,359,236 +$388,868,676 $25.01 147
2025 Q3 128,332,503 $3,111,987,564 +$147,803,679 $24.25 124
2025 Q2 123,569,478 $1,623,678,828 -$30,690,539 $13.14 117
2025 Q1 124,913,742 $1,797,461,231 -$6,439,160 $14.38 130
2024 Q4 124,413,136 $2,083,915,345 +$72,898,202 $16.75 114
2024 Q3 108,571,980 $1,737,489,847 +$315,516,266 $15.99 101
2024 Q2 86,506,981 $781,158,600 +$108,671,569 $9.03 79
2024 Q1 74,395,267 $840,663,455 +$66,659,727 $11.30 69
2023 Q4 71,279,084 $567,382,245 +$15,317,885 $7.96 56
2023 Q3 72,578,425 $469,582,127 +$14,480,766 $6.47 46
2023 Q2 70,339,619 $435,403,089 +$25,413,534 $6.19 43
2023 Q1 66,895,058 $257,540,618 +$13,125,714 $3.85 42
2022 Q4 62,684,642 $194,353,719 +$5,918,047 $3.10 41
2022 Q3 71,808,783 $288,649,039 -$842,289 $4.02 41
2022 Q2 71,775,040 $349,577,531 -$37,633,222 $4.87 40
2022 Q1 74,581,035 $669,057,512 +$23,146,015 $8.97 40
2021 Q4 71,873,880 $807,766,000 +$18,577,946 $11.26 46
2021 Q3 52,983,439 $881,813,000 +$147,088,157 $16.70 38
2021 Q2 47,409,892 $1,045,414,000 +$1,045,413,999 $22.21 49
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