| Reporting Name | Ownership % | Change | Value $ | Shares owned | Change | Activity % | Price | Form | Report date | Filing time |
|---|---|---|---|---|---|---|---|---|---|---|
| Avoro Capital Advisors LLC | 5.5% | $614,244,077 | 8,515,792 | $72.13 | 13G/A | 31 Dec 2025 | 17 Feb 2026, 09:03 |
| Holdings date | Option | Weight | Change | Value $ | Shares | Change | Activity % | Price | All Holders |
|---|---|---|---|---|---|---|---|---|---|
| 31 Dec 2025 | 3.9% | -1.6% | $393,469,150 | 5,455,000 | -2,190,000 | -29% | $72.13 | Q4 2025 | |
| 30 Sep 2025 | 4.3% | +0.34% | $333,092,650 | 7,645,000 | +595,000 | +8.4% | $43.57 | Q3 2025 | |
| 30 Jun 2025 | 3.5% | -0.29% | $200,220,000 | 7,050,000 | -575,000 | -7.5% | $28.40 | Q2 2025 | |
| 31 Mar 2025 | 3.5% | +0.06% | $225,090,000 | 7,625,000 | +125,000 | $29.52 | Q1 2025 | ||
| 31 Dec 2024 | 3.1% | +0.26% | $218,100,000 | 7,500,000 | +625,000 | +9.1% | $29.08 | Q4 2024 | |
| 30 Sep 2024 | 4.6% | +0.25% | $315,768,750 | 6,875,000 | +370,000 | +5.7% | $45.93 | Q3 2024 | |
| 30 Jun 2024 | 3.5% | +0.32% | $265,729,250 | 6,505,000 | +680,000 | +12% | $40.85 | Q2 2024 | |
| 31 Mar 2024 | 1.7% | +0.99% | $148,654,000 | 5,825,000 | +3,315,000 | +132% | $25.52 | Q1 2024 | |
| 31 Dec 2023 | 0.31% | 0% | $22,715,500 | 2,510,000 | 0 | $9.05 | Q4 2023 | ||
| 30 Sep 2023 | 0.25% | 0% | $16,013,800 | 2,510,000 | 0 | $6.38 | Q3 2023 | ||
| 30 Jun 2023 | 0.38% | 0% | $27,835,900 | 2,510,000 | 0 | $11.09 | Q2 2023 | ||
| 31 Mar 2023 | 0.57% | +0.1% | $38,528,500 | 2,510,000 | +460,000 | +22% | $15.35 | Q1 2023 | |
| 31 Dec 2022 | 0.68% | +0.2% | $45,489,500 | 2,050,000 | +600,000 | +41% | $22.19 | Q4 2022 | |
| 30 Sep 2022 | 0.44% | +0.05% | $23,679,000 | 1,450,000 | +150,000 | +12% | $16.33 | Q3 2022 | |
| 30 Jun 2022 | 0.37% | 0% | $18,889,000 | 1,300,000 | 0 | $14.53 | Q2 2022 | ||
| 31 Mar 2022 | 0.44% | +0.02% | $24,011,000 | 1,300,000 | +70,000 | +5.7% | $18.47 | Q1 2022 | |
| 31 Dec 2021 | 0.5% | +0.03% | $29,237,000 | 1,230,000 | +80,000 | +7% | $23.77 | Q4 2021 | |
| 30 Sep 2021 | 0.45% | +0.24% | $28,325,000 | 1,150,000 | +605,000 | +111% | $24.63 | Q3 2021 | |
| 30 Jun 2021 | 0.23% | 0% | $13,467,000 | 545,000 | 0 | $24.71 | Q2 2021 | ||
| 31 Mar 2021 | 0.21% | 0% | $11,886,000 | 545,000 | 0 | $21.81 | Q1 2021 | ||
| 31 Dec 2020 | 0.24% | 0% | $13,908,000 | 545,000 | 0 | $25.52 | Q4 2020 | ||
| 30 Sep 2020 | 0.22% | -0.02% | $15,342,000 | 545,000 | -40,000 | -6.8% | $28.15 | Q3 2020 | |
| 30 Jun 2020 | 0.33% | +0.33% | $16,532,000 | 585,000 | +585,000 | NEW | $28.26 | Q2 2020 |