Apogee Therapeutics, Inc. - COMMON STOCK (APGE)
CUSIP: 03770N101
Q4 2025 13F Holders as of 31 Dec 2025
- Type / Class
- Equity / COMMON STOCK
- Shares outstanding
- 61,257,262
- Total 13F shares
- 69,771,331
- Share change
- +9,434,359
- Total reported value
- $5,266,434,045
- Put/Call ratio
- 43%
- Price per share
- $75.48
- Number of holders
- 206
- Value change
- +$762,006,154
- Number of buys
- 130
- Number of sells
- 63
Quarterly Holders Quick Answers
What is CUSIP 03770N101?
CUSIP 03770N101 identifies APGE - Apogee Therapeutics, Inc. - COMMON STOCK in SEC institutional holdings data.
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Recent filing periods for CUSIP 03770N101:
Top shareholders of APGE - Apogee Therapeutics, Inc. - COMMON STOCK (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| WELLINGTON MANAGEMENT GROUP LLP |
13D/G
13F
|
Company |
8.7%
|
4,746,585
|
$374,980,215 | -$10,946,319 | 31 Dec 2025 | |
| VR Adviser, LLC |
13F
|
Company |
14%
|
8,493,321
|
$337,439,643 | — | 30 Sep 2025 | |
| FMR LLC |
13F
13D/G
|
Company |
15%
from 13D/G
|
6,916,462
|
$274,791,036 | — | 30 Sep 2025 | |
| RTW INVESTMENTS, LP |
13D/G
13F
|
Company |
4.9%
|
2,712,097
|
$214,255,663 | $0 | 31 Dec 2025 | |
| BlackRock, Inc. |
13D/G
13F
|
Company |
5.5%
|
2,518,725
|
$109,396,539 | $0 | 30 Jun 2025 | |
| VANGUARD GROUP INC |
13F
|
Company |
3.7%
|
2,245,631
|
$89,218,920 | — | 30 Sep 2025 | |
| DRIEHAUS CAPITAL MANAGEMENT LLC |
13D/G
13F
|
Company |
4.7%
|
2,158,502
|
$85,757,284 | $0 | 30 Sep 2025 | |
| Fairmount Funds Management LLC |
13F
|
Company |
3.3%
|
2,048,647
|
$81,392,745 | — | 30 Sep 2025 | |
| STATE STREET CORP |
13F
|
Company |
2.7%
|
1,655,548
|
$65,774,922 | — | 30 Sep 2025 | |
| Paradigm Biocapital Advisors LP |
13F
|
Company |
2.5%
|
1,521,757
|
$60,459,406 | — | 30 Sep 2025 | |
| BRAIDWELL LP |
13F
|
Company |
2.3%
|
1,438,745
|
$57,161,339 | — | 30 Sep 2025 | |
| ALLIANCEBERNSTEIN L.P. |
13F
|
Company |
2.3%
|
1,419,132
|
$56,382,114 | — | 30 Sep 2025 | |
| PERCEPTIVE ADVISORS LLC |
13F
|
Company |
2.2%
|
1,351,989
|
$53,714,523 | — | 30 Sep 2025 | |
| Affinity Asset Advisors, LLC |
13F
|
Company |
1.9%
|
1,173,426
|
$46,620,215 | — | 30 Sep 2025 | |
| CITADEL ADVISORS LLC |
13F
|
Company |
1.9%
|
1,169,244
|
$46,454,065 | — | 30 Sep 2025 | |
| JPMORGAN CHASE & CO |
13F
|
Company |
1.9%
|
1,137,731
|
$45,202,052 | — | 30 Sep 2025 | |
| MERCER GLOBAL ADVISORS INC /ADV |
13F
|
Company |
1.6%
|
970,581
|
$38,561,183 | — | 30 Sep 2025 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
1.5%
|
892,203
|
$35,453,920 | — | 30 Sep 2025 | |
| UBS Group AG |
13F
|
Company |
1.3%
|
799,465
|
$31,762,745 | — | 30 Sep 2025 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
|
Company |
1.2%
|
750,529
|
$29,820,000 | — | 30 Sep 2025 | |
| FRANKLIN RESOURCES INC |
13F
|
Company |
1.2%
|
730,761
|
$29,033,130 | — | 30 Sep 2025 | |
| BARCLAYS PLC |
13F
|
Company |
1%
|
642,316
|
$25,519,215 | — | 30 Sep 2025 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
0.98%
|
599,616
|
$23,822,744 | — | 30 Sep 2025 | |
| Jefferies Financial Group Inc. |
13F
|
Company |
0.93%
|
568,084
|
$22,569,977 | — | 30 Sep 2025 | |
| Sofinnova Investments, Inc. |
13F
|
Company |
0.92%
|
565,417
|
$22,464,017 | — | 30 Sep 2025 | |
| Polar Capital Holdings Plc |
13F
|
Company |
0.86%
|
524,094
|
$20,822,255 | — | 30 Sep 2025 | |
| Novo Holdings A/S |
13F
|
Company |
0.82%
|
500,000
|
$19,865,000 | — | 30 Sep 2025 | |
| JANUS HENDERSON GROUP PLC |
13F
|
Company |
0.79%
|
485,978
|
$19,308,297 | — | 30 Sep 2025 | |
| MORGAN STANLEY |
13F
|
Company |
0.76%
|
464,963
|
$18,473,006 | — | 30 Sep 2025 | |
| MILLENNIUM MANAGEMENT LLC |
13F
|
Company |
0.7%
|
430,463
|
$17,102,295 | — | 30 Sep 2025 | |
| Vestal Point Capital, LP |
13F
|
Company |
0.69%
|
425,000
|
$16,885,250 | — | 30 Sep 2025 | |
| First Turn Management, LLC |
13F
|
Company |
0.66%
|
402,811
|
$16,003,681 | — | 30 Sep 2025 | |
| BANK OF AMERICA CORP /DE/ |
13F
|
Company |
0.64%
|
393,912
|
$15,650,123 | — | 30 Sep 2025 | |
| Nimish P. Shah |
3/4/5
|
Director |
—
mixed-class rows
|
380,314
mixed-class rows
|
$14,999,936 | +$14,999,936 | 10 Oct 2025 | |
| FRONTIER CAPITAL MANAGEMENT CO LLC |
13F
|
Company |
0.61%
|
374,407
|
$14,875,190 | — | 30 Sep 2025 | |
| Opaleye Management Inc. |
13F
|
Company |
0.59%
|
363,257
|
$14,432,201 | — | 30 Sep 2025 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.52%
|
319,903
|
$12,709,746 | — | 30 Sep 2025 | |
| GREAT POINT PARTNERS LLC |
13F
|
Company |
0.5%
|
304,000
|
$12,077,920 | — | 30 Sep 2025 | |
| Commodore Capital LP |
13F
|
Company |
0.47%
|
290,000
|
$11,521,700 | — | 30 Sep 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.46%
|
284,483
|
$11,302,509 | — | 30 Sep 2025 | |
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
13F
|
Company |
0.38%
|
235,000
|
$9,336,550 | — | 30 Sep 2025 | |
| VICTORY CAPITAL MANAGEMENT INC |
13F
|
Company |
0.35%
|
217,213
|
$8,629,872 | — | 30 Sep 2025 | |
| SCHRODER INVESTMENT MANAGEMENT GROUP |
13F
|
Company |
0.35%
|
215,846
|
$8,597,146 | — | 30 Sep 2025 | |
| TANG CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.33%
|
200,000
|
$7,946,000 | — | 30 Sep 2025 | |
| Blackstone Inc. |
13F
|
Company |
0.31%
|
190,352
|
$7,562,685 | — | 30 Sep 2025 | |
| SG Americas Securities, LLC |
13F
|
Company |
0.22%
|
134,226
|
$5,333,000 | — | 30 Sep 2025 | |
| Granahan Investment Management, LLC |
13F
|
Company |
0.22%
|
132,400
|
$5,260,252 | — | 30 Sep 2025 | |
| Universal- Beteiligungs- und Servicegesellschaft mbH |
13F
|
Individual |
0.21%
|
131,436
|
$5,221,952 | — | 30 Sep 2025 | |
| Capital World Investors |
13F
|
Company |
0.21%
|
127,618
|
$5,070,263 | — | 30 Sep 2025 | |
| S.c.a. Candriam |
13F
|
Individual |
0.21%
|
126,081
|
$5,009,198 | — | 30 Sep 2025 |
Institutional Holders of Apogee Therapeutics, Inc. - COMMON STOCK (APGE) as of Q4 2025
As of 31 Dec 2025,
Apogee Therapeutics, Inc. - COMMON STOCK (APGE) was held by
206 institutional
shareholders
that filed Form 13F with the SEC.
Together, they reported ownership of
69,771,331 shares.
The largest 10 holders included
VR ADVISER, LLC, FMR LLC, WELLINGTON MANAGEMENT GROUP LLP, BlackRock, Inc., VANGUARD GROUP INC, T. Rowe Price Investment Management, Inc., RTW INVESTMENTS, LP, PERCEPTIVE ADVISORS LLC, Driehaus Capital Management LLC, and JANUS HENDERSON GROUP PLC.
This page lists
206
institutional shareholders reporting positions in this security
for the Q4 2025 filing period.
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
Compare Q4 2025 vs Q3 2025 Across Filers
Q3 2025 holders
173
Q4 2025 holders
206
Holder diff
33
| Investor | Q3 2025 Shares | Q4 2025 Shares | Share Diff | Share Chg % | Q3 2025 Value $ | Q4 2025 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).
Quarterly Holders Trend
Quarterly Value Trend
Quarterly Shares Trend
* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.
An asterisk sign (*) next to the price indicates that the price is likely invalid.