| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| CVI Investments, Inc. | 4.9% | -4% | $1,470,000 | 1,000,000 | 0% | CVI Investments, Inc. | 31 Mar 2025 |
As of 31 Dec 2025, 51 institutional investors reported holding 4,211,653 shares of Annovis Bio, Inc. - Common Stock, par value $0.0001 per share (ANVS). This represents 21% of the company’s total 19,607,843 outstanding shares.
The largest institutional shareholders of Annovis Bio, Inc. - Common Stock, par value $0.0001 per share (ANVS) together control 21% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| VANGUARD GROUP INC | 4.7% | 923,201 | +25% | 0% | $3,194,275 |
| MARSHALL WACE, LLP | 3.7% | 725,862 | 0% | $2,511,482 | |
| TWO SIGMA INVESTMENTS, LP | 2.8% | 551,837 | 0% | $1,909,356 | |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1.5% | 303,287 | +39% | 0% | $1,049,373 |
| JANE STREET GROUP, LLC | 1.3% | 251,157 | 0% | $869,003 | |
| GEODE CAPITAL MANAGEMENT, LLC | 1.1% | 222,132 | +21% | 0% | $768,711 |
| D.A. DAVIDSON & CO. | 0.82% | 160,779 | 0% | $556,295 | |
| BlackRock, Inc. | 0.71% | 139,533 | +73% | 0% | $482,784 |
| NORTHERN TRUST CORP | 0.62% | 120,862 | -0.16% | 0% | $418,182 |
| Merit Financial Group, LLC | 0.41% | 81,316 | 0% | 0% | $281,353 |
| STATE STREET CORP | 0.38% | 74,035 | +93% | 0% | $256,161 |
| GROUP ONE TRADING LLC | 0.35% | 69,126 | +100% | 0.01% | $239,176 |
| OMERS ADMINISTRATION Corp | 0.32% | 62,100 | 0% | $214,866 | |
| TWO SIGMA ADVISERS, LP | 0.23% | 45,221 | 0% | $156,465 | |
| Greenwich Wealth Management LLC | 0.22% | 42,400 | -11% | 0.01% | $147,000 |
| Wescott Financial Advisory Group, LLC | 0.21% | 41,607 | 0% | 0.01% | $143,960 |
| First National Trust Co | 0.2% | 40,000 | +167% | 0% | $138,400 |
| UBS Group AG | 0.16% | 30,643 | +4741% | 0% | $106,025 |
| Sherry Group, Inc. | 0.14% | 27,270 | 0% | 0.1% | $94,354 |
| Dakota Wealth Management | 0.13% | 26,200 | 0% | $90,652 | |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 0.12% | 24,400 | +26% | 0% | $84,424 |
| Sterling Investment Advisors, Ltd. | 0.12% | 23,416 | 0% | 0.02% | $81,019 |
| NewEdge Advisors, LLC | 0.1% | 20,500 | 0% | $70,930 | |
| Bank of New York Mellon Corp | 0.1% | 20,058 | +5.2% | 0% | $69,401 |
| Wealthspire Advisors, LLC | 0.1% | 20,000 | +100% | 0% | $69,200 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 4,211,653 | $14,571,646 | +$7,933,097 | $3.46 | 51 |
| 2025 Q3 | 2,024,516 | $4,189,707 | +$428,194 | $2.07 | 42 |
| 2025 Q2 | 1,811,877 | $3,929,691 | -$326,377 | $2.17 | 42 |
| 2025 Q1 | 2,086,860 | $3,130,127 | -$507,485 | $1.50 | 43 |
| 2024 Q4 | 1,575,712 | $7,926,263 | +$1,704,856 | $5.03 | 40 |
| 2024 Q3 | 1,179,026 | $9,503,457 | +$1,923,073 | $8.06 | 35 |
| 2024 Q2 | 984,218 | $5,669,358 | -$2,073,596 | $5.76 | 29 |
| 2024 Q1 | 1,190,821 | $14,170,568 | -$404,974 | $11.90 | 29 |
| 2023 Q4 | 1,204,452 | $22,522,950 | +$2,419,829 | $18.70 | 35 |
| 2023 Q3 | 1,111,889 | $10,551,231 | -$1,631,804 | $9.49 | 28 |
| 2023 Q2 | 1,278,556 | $18,270,029 | +$7,489,629 | $14.29 | 27 |
| 2023 Q1 | 752,202 | $11,588,203 | +$250,861 | $15.41 | 22 |
| 2022 Q4 | 736,307 | $9,887,632 | +$230,554 | $13.43 | 21 |
| 2022 Q3 | 718,857 | $9,847,000 | -$399,073 | $13.70 | 20 |
| 2022 Q2 | 770,387 | $8,735,000 | -$1,477,097 | $11.33 | 24 |
| 2022 Q1 | 888,924 | $11,867,000 | -$3,780,511 | $13.35 | 22 |
| 2021 Q4 | 1,115,969 | $19,619,000 | -$2,600,801 | $17.58 | 29 |
| 2021 Q3 | 1,140,634 | $36,227,000 | -$24,730,573 | $31.74 | 36 |
| 2021 Q2 | 1,272,982 | $108,947,000 | +$39,294,497 | $85.59 | 56 |
| 2021 Q1 | 834,363 | $23,108,000 | +$2,874,108 | $27.90 | 29 |
| 2020 Q4 | 759,911 | $5,730,000 | +$93,763 | $7.55 | 12 |
| 2020 Q3 | 315,551 | $1,518,000 | +$388,364 | $4.81 | 11 |
| 2020 Q2 | 243,843 | $1,060,000 | +$220,698 | $4.35 | 8 |
| 2020 Q1 | 192,761 | $580,000 | +$580,000 | $3.01 | 6 |