Security Snapshot

Annovis Bio, Inc. - Common Stock, par value $0.0001 per share (ANVS) Institutional Ownership

CUSIP: 03615A108

13F Institutional Holders and Ownership History from Q1 2020 to Q1 2026

Latest Period

Q4 2025

Institutions Reporting

52

Shares (Excl. Options)

4,237,986

Price

$3.46

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Type / Class
Equity / Common Stock, par value $0.0001 per share
Symbol
ANVS on NYSE
Shares outstanding
19,607,843
Price per share
$2.23
All holders as of 31 Dec 2025
Q4 2025
Total 13F shares
4,237,986
Total reported value
$14,662,646
% of total 13F portfolios
0%
Share change
+2,215,448
Value change
+$8,024,097
Number of holders
52
Price from insider filings
$2.23
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors

Quick Takeaways

  • ANVS - Annovis Bio, Inc. - Common Stock, par value $0.0001 per share is tracked under CUSIP 03615A108.
  • 52 institutions reported positions in Q4 2025.
  • 1 significant owner is listed from Schedule 13D/13G reporting.

What Changed

  • Holder count moved from 52 to 8 between Q4 2025 and Q1 2026.
  • Reported value moved from $14,662,646 to $270,280.

Why This Matters

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Source Evidence

Source: SEC Form 13F

Latest holder context comes from 52 institutions filings for Q4 2025.

Open SEC Evidence

Investment Quick Answers

What is CUSIP 03615A108?
CUSIP 03615A108 identifies ANVS - Annovis Bio, Inc. - Common Stock, par value $0.0001 per share in SEC 13F datasets.

Where can I see the latest institutional holders?
Review the Q4 2025 holders report and the ownership history table below.

Significant Owners of Annovis Bio, Inc. - Common Stock, par value $0.0001 per share (ANVS) based on Schedule 13D/G filings

Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
CVI Investments, Inc. 4.9% -4% $1,470,000 1,000,000 0% CVI Investments, Inc. 31 Mar 2025

As of 31 Dec 2025, 52 institutional investors reported holding 4,237,986 shares of Annovis Bio, Inc. - Common Stock, par value $0.0001 per share (ANVS). This represents 22% of the company’s total 19,607,843 outstanding shares.

Top 25 Institutional Shareholders

The largest institutional shareholders of Annovis Bio, Inc. - Common Stock, par value $0.0001 per share (ANVS) together control 21% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.

Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
VANGUARD GROUP INC 4.7% 923,201 +25% 0% $3,194,275
MARSHALL WACE, LLP 3.7% 725,862 0% $2,511,482
TWO SIGMA INVESTMENTS, LP 2.8% 551,837 0% $1,909,356
SUSQUEHANNA INTERNATIONAL GROUP, LLP 1.5% 303,287 +39% 0% $1,049,373
JANE STREET GROUP, LLC 1.3% 251,157 0% $869,003
GEODE CAPITAL MANAGEMENT, LLC 1.1% 222,132 +21% 0% $768,711
D.A. DAVIDSON & CO. 0.82% 160,779 0% $556,295
BlackRock, Inc. 0.71% 139,533 +73% 0% $482,784
NORTHERN TRUST CORP 0.62% 120,862 -0.16% 0% $418,182
Merit Financial Group, LLC 0.41% 81,316 0% 0% $281,353
STATE STREET CORP 0.38% 74,035 +93% 0% $256,161
GROUP ONE TRADING LLC 0.35% 69,126 +100% 0.01% $239,176
OMERS ADMINISTRATION Corp 0.32% 62,100 0% $214,866
TWO SIGMA ADVISERS, LP 0.23% 45,221 0% $156,465
Greenwich Wealth Management LLC 0.22% 42,400 -11% 0.01% $147,000
Wescott Financial Advisory Group, LLC 0.21% 41,607 0% 0.01% $143,960
First National Trust Co 0.2% 40,000 +167% 0% $138,400
UBS Group AG 0.16% 30,643 +4741% 0% $106,025
Sherry Group, Inc. 0.14% 27,270 0% 0.1% $94,354
Virtu Financial LLC 0.13% 26,333 0% $91,000
Dakota Wealth Management 0.13% 26,200 0% $90,652
BRIDGEWAY CAPITAL MANAGEMENT, LLC 0.12% 24,400 +26% 0% $84,424
Sterling Investment Advisors, Ltd. 0.12% 23,416 0% 0.02% $81,019
NewEdge Advisors, LLC 0.1% 20,500 0% $70,930
Bank of New York Mellon Corp 0.1% 20,058 +5.2% 0% $69,401

Institutional Holders of Annovis Bio, Inc. - Common Stock, par value $0.0001 per share (ANVS) across Reporting Periods

Period Reported Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q1 121,305 $270,280 -$40,211 $2.23 8
2025 Q4 4,237,986 $14,662,646 +$8,024,097 $3.46 52
2025 Q3 2,024,516 $4,189,707 +$428,194 $2.07 42
2025 Q2 1,811,877 $3,929,691 -$326,377 $2.17 42
2025 Q1 2,086,860 $3,130,127 -$507,485 $1.50 43
2024 Q4 1,575,712 $7,926,263 +$1,704,856 $5.03 40
2024 Q3 1,179,026 $9,503,457 +$1,923,073 $8.06 35
2024 Q2 984,218 $5,669,358 -$2,073,596 $5.76 29
2024 Q1 1,190,821 $14,170,568 -$404,974 $11.90 29
2023 Q4 1,204,452 $22,522,950 +$2,419,829 $18.70 35
2023 Q3 1,111,889 $10,551,231 -$1,631,804 $9.49 28
2023 Q2 1,278,556 $18,270,029 +$7,489,629 $14.29 27
2023 Q1 752,202 $11,588,203 +$250,861 $15.41 22
2022 Q4 736,307 $9,887,632 +$230,554 $13.43 21
2022 Q3 718,857 $9,847,000 -$399,073 $13.70 20
2022 Q2 770,387 $8,735,000 -$1,477,097 $11.33 24
2022 Q1 888,924 $11,867,000 -$3,780,511 $13.35 22
2021 Q4 1,115,969 $19,619,000 -$2,600,801 $17.58 29
2021 Q3 1,140,634 $36,227,000 -$24,730,573 $31.74 36
2021 Q2 1,272,982 $108,947,000 +$39,294,497 $85.59 56
2021 Q1 834,363 $23,108,000 +$2,874,108 $27.90 29
2020 Q4 759,911 $5,730,000 +$93,763 $7.55 12
2020 Q3 315,551 $1,518,000 +$388,364 $4.81 11
2020 Q2 243,843 $1,060,000 +$220,698 $4.35 8
2020 Q1 192,761 $580,000 +$580,000 $3.01 6