Security Snapshot

Annexon, Inc. - Common Stock, par value $0.001 per share (ANNX) Institutional Ownership

CUSIP: 03589W102

13F Institutional Holders and Ownership History from Q3 2020 to Q1 2026

Latest Period

Q1 2026

Institutions Reporting

217

Shares (Excl. Options)

155,947,902

Price

$5.54

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Latest holder snapshot 5 signals
Portfolio coverage rank
0%
Share change
+18,101,698
Value change
+$101,291,739
Number of holders
217
Issuer context Names, identifiers, and filing context for this profile. 3 identity fields
Shares outstanding
161,077,278
SEC-reported price per share
$5.44
Insider filing price
$5.44
13F Shares, Excluding Options vs Price
13F Value, Excluding Options
Total Investors

Key facts

  • ANNX - Annexon, Inc. - Common Stock, par value $0.001 per share is tracked under CUSIP 03589W102.
  • 217 institutions reported positions in Q1 2026.
  • 7 significant owners is listed from Schedule 13D/13G reporting.

Change

  • Holder count moved from 169 to 217 between Q4 2025 and Q1 2026.
  • SEC-reported value moved from $687,297,160 to $863,678,650.

Research use

  • You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
  • 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.

Evidence

Source: SEC Form 13F

Latest holder context comes from 217 institutions filings for Q1 2026.

Open SEC evidence

Security key

03589W102

Latest holder period

Q1 2026

13F holders

217

13D/G owners

7

CIK / CUSIP context first

13D/G owners

Significant owners

Large-stake holder rows connected to Schedule 13D/G evidence.

Rows
7
Security
ANNX
Filer Ownership Change % Holdings Value Net Change Nb Shares Change % Reporting Name Report Period
Redmile Group, LLC 9.9% $85,778,935 15,427,866 Redmile Group, LLC 31 Dec 2025
Satter Muneer A 7.2% $36,032,262 10,444,134 Satter Muneer A 19 Nov 2025
FMR LLC 7.1% -30% $51,316,801 -$4,310,639 10,222,470 -7.7% FMR LLC 31 Dec 2025
BlackRock, Inc. 6.1% $44,521,150 8,868,755 BlackRock, Inc. 31 Dec 2025
BIOTECHNOLOGY VALUE FUND L P 5.4% $48,187,878 8,698,173 BVF PARTNERS L P/IL 31 Mar 2026
Bain Capital Life Sciences Fund, L.P. 4.9% $9,973,231 5,249,069 BCLS I Investco, LP 31 Dec 2024
Point72 Asset Management, L.P. 0.1% $181,317 95,430 Point72 Asset Management, L.P. 31 Mar 2025

As of 31 Mar 2026, 217 institutional investors reported holding 155,947,902 shares of Annexon, Inc. - Common Stock, par value $0.001 per share (ANNX). This represents 97% of the company’s total 161,077,278 outstanding shares.

13F concentration

Top 25 institutional shareholders

Largest 13F positions for this security by reported shares and value.

Top holder share
76%
Institution Ownership % Shares Held Share Change % Portfolio % Holdings Value
Redmile Group, LLC 9% 14,549,768 +45% 5.3% $80,605,715
BlackRock, Inc. 6.8% 10,938,509 +22% 0% $60,599,340
FMR LLC 6.6% 10,635,648 +4% 0% $58,921,492
BVF INC/IL 5.4% 8,698,173 -4.7% 1.5% $48,187,878
STATE STREET CORP 4.3% 6,919,255 +49% 0% $38,332,673
VANGUARD CAPITAL MANAGEMENT LLC 3.7% 5,956,589 0% 0% $32,999,503
Bain Capital Life Sciences Investors, LLC 3.2% 5,212,674 -0.69% 2.6% $28,878,214
Bellevue Group AG 3.2% 5,157,290 0% 0.68% $28,571,387
MAK CAPITAL ONE LLC 2.9% 4,724,043 +60% 4.3% $26,171,198
ADAGE CAPITAL PARTNERS GP, L.L.C. 2.7% 4,300,000 -22% 0.04% $23,822,000
BANK OF AMERICA CORP /DE/ 2.6% 4,259,995 +165% 0% $23,600,372
Nuveen, LLC 2.6% 4,246,330 +46% 0.01% $23,524,668
Siren, L.L.C. 2.5% 3,958,646 0.61% $21,930,899
Balyasny Asset Management L.P. 2.4% 3,886,909 +18% 0.04% $21,533,476
AMERIPRISE FINANCIAL INC 2.1% 3,449,121 -21% 0% $19,108,132
GEODE CAPITAL MANAGEMENT, LLC 2.1% 3,377,823 +16% 0% $18,717,903
Qube Research & Technologies Ltd 1.9% 3,114,314 +31% 0.02% $17,253,300
Palo Alto Investors LP 1.8% 2,948,090 +24% 2.5% $16,332,419
MORGAN STANLEY 1.7% 2,735,970 -4.2% 0% $15,157,274
GREAT POINT PARTNERS LLC 1.6% 2,500,000 3.4% $13,850,000
Woodline Partners LP 1.5% 2,337,137 -42% 0.05% $12,947,739
Opaleye Management Inc. 1.4% 2,331,761 -10% 1.8% $12,917,956
GOLDMAN SACHS GROUP INC 1.3% 2,152,880 +22% 0% $11,926,955
Point72 Asset Management, L.P. 1.2% 1,871,795 +404% 0.02% $10,369,744
VANGUARD PORTFOLIO MANAGEMENT LLC 0.92% 1,483,090 0% 0% $8,216,319

Quarter history

Institutional holders across reporting periods

Holder count, reported shares/value, and median price by quarter.

Periods
23
Latest
Q1 2026
Rows shown
1-23 of 23
Period 13F Shares, Excl. Options Value, Excl. Options Value Change Price (Median) Investors
2026 Q1 155,947,902 $863,678,650 +$101,291,739 $5.54 217
2025 Q4 136,923,781 $687,297,160 +$183,807,666 $5.02 169
2025 Q3 101,380,733 $309,219,194 +$11,142,271 $3.05 143
2025 Q2 99,449,067 $238,679,312 +$759,672 $2.40 127
2025 Q1 99,491,910 $192,036,870 -$14,234,585 $1.93 146
2024 Q4 111,907,572 $574,088,227 +$7,286,342 $5.13 151
2024 Q3 109,990,075 $651,286,147 +$12,076,588 $5.92 141
2024 Q2 107,381,777 $526,166,969 +$50,550,360 $4.90 139
2024 Q1 94,762,361 $679,439,424 +$107,931,991 $7.17 125
2023 Q4 80,514,496 $365,538,892 +$125,501,716 $4.54 98
2023 Q3 53,312,574 $125,814,682 -$910,472 $2.36 91
2023 Q2 53,372,682 $187,869,879 -$1,833,578 $3.52 93
2023 Q1 53,953,057 $207,583,535 +$11,598,782 $3.85 98
2022 Q4 47,049,561 $243,269,266 +$3,854,655 $5.17 81
2022 Q3 46,270,615 $285,949,000 +$49,950,788 $6.18 69
2022 Q2 38,409,280 $144,864,000 +$5,360,704 $3.77 74
2022 Q1 38,555,259 $105,261,060 -$23,763,559 $2.73 96
2021 Q4 38,766,276 $445,683,894 +$6,730,750 $11.49 94
2021 Q3 38,055,922 $708,635,015 -$28,821,254 $18.61 81
2021 Q2 38,854,536 $873,668,672 +$29,687,677 $22.51 73
2021 Q1 37,426,974 $1,040,768,344 +$38,809,119 $27.84 72
2020 Q4 36,208,873 $904,277,496 -$17,927,945 $25.03 70
2020 Q3 34,842,574 $1,039,585,431 +$1,039,585,431 $30.23 65
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