| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Satter Muneer A | 7.2% | $36,032,262 | 10,444,134 | Satter Muneer A | 19 Nov 2025 | |||
| FMR LLC | 7.1% | -30% | $51,316,801 | -$4,310,639 | 10,222,470 | -7.7% | FMR LLC | 31 Dec 2025 |
| BlackRock, Inc. | 6.1% | $44,521,150 | 8,868,755 | BlackRock, Inc. | 31 Dec 2025 | |||
| VANGUARD GROUP INC | 5.3% | +8.2% | $17,797,092 | +$1,389,132 | 5,835,112 | +8.5% | The Vanguard Group | 30 Sep 2025 |
| Bain Capital Life Sciences Fund, L.P. | 4.9% | $9,973,231 | 5,249,069 | BCLS I Investco, LP | 31 Dec 2024 | |||
| Point72 Asset Management, L.P. | 0.1% | $181,317 | 95,430 | Point72 Asset Management, L.P. | 31 Mar 2025 |
As of 31 Dec 2025, 94 institutional investors reported holding 44,873,015 shares of Annexon, Inc. - COMMON STOCK (ANNX). This represents 31% of the company’s total 143,978,456 outstanding shares.
The largest institutional shareholders of Annexon, Inc. - COMMON STOCK (ANNX) together control 30% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| BlackRock, Inc. | 6.2% | 8,960,434 | +13% | 0% | $44,981,380 |
| VANGUARD GROUP INC | 5.4% | 7,753,387 | +33% | 0% | $38,922,003 |
| STATE STREET CORP | 3.2% | 4,652,185 | +127% | 0% | $23,353,969 |
| Nuveen, LLC | 2% | 2,915,324 | +327% | 0% | $14,634,927 |
| GEODE CAPITAL MANAGEMENT, LLC | 2% | 2,902,896 | +19% | 0% | $14,576,148 |
| MORGAN STANLEY | 2% | 2,856,143 | -5.7% | 0% | $14,337,838 |
| GOLDMAN SACHS GROUP INC | 1.2% | 1,768,745 | -26% | 0% | $8,879,100 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0.73% | 1,057,060 | +34% | 0% | $5,306,441 |
| MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 0.63% | 903,439 | -7.8% | 0% | $4,535,264 |
| ACADIAN ASSET MANAGEMENT LLC | 0.6% | 861,245 | +62% | 0.01% | $4,321,000 |
| RENAISSANCE TECHNOLOGIES LLC | 0.56% | 802,600 | +6.5% | 0.01% | $4,029,052 |
| DIMENSIONAL FUND ADVISORS LP | 0.5% | 718,680 | -6.3% | 0% | $3,607,910 |
| SIRIOS CAPITAL MANAGEMENT L P | 0.49% | 710,256 | -27% | 0.44% | $3,565,485 |
| JACOBS LEVY EQUITY MANAGEMENT, INC | 0.47% | 683,879 | +2927% | 0.01% | $3,433,073 |
| MUTUAL OF AMERICA CAPITAL MANAGEMENT LLC | 0.45% | 642,038 | -40% | 0.03% | $3,223,031 |
| KENNEDY CAPITAL MANAGEMENT LLC | 0.44% | 639,902 | -0.09% | 0.07% | $3,212,308 |
| WELLS FARGO & COMPANY/MN | 0.4% | 573,748 | +40% | 0% | $2,880,214 |
| DEUTSCHE BANK AG\ | 0.39% | 560,744 | -63% | 0% | $2,814,935 |
| Hennion & Walsh Asset Management, Inc. | 0.37% | 534,986 | +12% | 0.09% | $2,685,630 |
| MARSHALL WACE, LLP | 0.36% | 520,998 | 0% | $2,615,410 | |
| JANE STREET GROUP, LLC | 0.36% | 513,836 | +134% | 0% | $2,579,457 |
| UBS Group AG | 0.26% | 377,104 | +8.9% | 0% | $1,893,062 |
| Bank of New York Mellon Corp | 0.25% | 361,677 | +17% | 0% | $1,815,619 |
| BARCLAYS PLC | 0.2% | 289,963 | +96% | 0% | $1,455,614 |
| AMERICAN CENTURY COMPANIES INC | 0.17% | 251,158 | +6.1% | 0% | $1,260,813 |
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2025 Q4 | 44,873,015 | $225,199,582 | +$32,693,203 | $5.02 | 94 |
| 2025 Q3 | 101,393,828 | $309,259,134 | +$11,182,352 | $3.05 | 144 |
| 2025 Q2 | 99,449,067 | $238,679,312 | +$759,672 | $2.40 | 127 |
| 2025 Q1 | 99,491,910 | $192,036,870 | -$14,234,585 | $1.93 | 146 |
| 2024 Q4 | 111,907,572 | $574,088,227 | +$7,286,342 | $5.13 | 151 |
| 2024 Q3 | 109,990,075 | $651,286,147 | +$12,076,588 | $5.92 | 141 |
| 2024 Q2 | 107,381,777 | $526,166,969 | +$50,550,360 | $4.90 | 139 |
| 2024 Q1 | 94,762,361 | $679,439,424 | +$107,931,991 | $7.17 | 125 |
| 2023 Q4 | 80,514,496 | $365,538,892 | +$125,501,716 | $4.54 | 98 |
| 2023 Q3 | 53,312,574 | $125,814,682 | -$910,472 | $2.36 | 91 |
| 2023 Q2 | 53,372,682 | $187,869,879 | -$1,833,578 | $3.52 | 93 |
| 2023 Q1 | 53,953,057 | $207,583,535 | +$11,598,782 | $3.85 | 98 |
| 2022 Q4 | 47,049,561 | $243,269,266 | +$3,854,655 | $5.17 | 81 |
| 2022 Q3 | 46,270,615 | $285,949,000 | +$49,950,788 | $6.18 | 69 |
| 2022 Q2 | 38,409,280 | $144,864,000 | +$5,360,704 | $3.77 | 74 |
| 2022 Q1 | 38,555,259 | $105,261,060 | -$23,763,559 | $2.73 | 96 |
| 2021 Q4 | 38,766,276 | $445,683,894 | +$6,730,750 | $11.49 | 94 |
| 2021 Q3 | 38,055,922 | $708,635,015 | -$28,821,254 | $18.61 | 81 |
| 2021 Q2 | 38,854,536 | $873,668,672 | +$29,687,677 | $22.51 | 73 |
| 2021 Q1 | 37,426,974 | $1,040,768,344 | +$38,809,119 | $27.84 | 72 |
| 2020 Q4 | 36,208,873 | $904,277,496 | -$17,927,945 | $25.03 | 70 |
| 2020 Q3 | 34,842,574 | $1,039,585,431 | +$1,039,585,431 | $30.23 | 65 |