Latest Period
Q4 2025
Security Snapshot
Annexon, Inc. - Common Stock (ANNX) Institutional Ownership
CUSIP: 03589W102
13F Institutional Holders and Ownership History from Q3 2020 to Q1 2026
Institutions Reporting
167
Shares (Excl. Options)
136,910,694
Price
$5.02
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- Type / Class
- Equity / Common Stock
- Symbol
- ANNX on Nasdaq
- Shares outstanding
- 155,837,030
- Price per share
- $5.54
- All holders as of 31 Dec 2025
- Q4 2025
- Total 13F shares
- 136,910,694
- Total reported value
- $687,231,703
- % of total 13F portfolios
- 0%
- Share change
- +35,062,169
- Value change
- +$183,803,680
- Number of holders
- 167
- Price from insider filings
- $5.54
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors
Quick Takeaways
- ANNX - Annexon, Inc. - Common Stock is tracked under CUSIP 03589W102.
- 167 institutions reported positions in Q4 2025.
- 6 significant owners is listed from Schedule 13D/13G reporting.
What Changed
- Holder count moved from 167 to 64 between Q4 2025 and Q1 2026.
- Reported value moved from $687,231,703 to $111,128,533.
Why This Matters
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Source Evidence
Source: SEC Form 13F
Open SEC Evidence
Latest holder context comes from 167 institutions filings for Q4 2025.
Investment Quick Answers
What is CUSIP 03589W102?
CUSIP 03589W102 identifies ANNX - Annexon, Inc. - Common Stock in SEC 13F datasets.
Where can I see the latest institutional holders?
Review the Q4 2025 holders report and the ownership history table below.
Next ownership checks
Use the next link that matches the question you still need to answer about this security.
- Latest 13F filings when you want to inspect fresh institutional portfolio moves.
- Latest Schedule 13D/13G reports when you need large-owner changes outside the 13F cycle.
- All institutional ownership pages to compare this security with other holder-history pages.
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP 03589W102:
Significant Owners of Annexon, Inc. - Common Stock (ANNX) based on Schedule 13D/G filings
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| Redmile Group, LLC | 9.9% | $85,778,935 | 15,427,866 | Redmile Group, LLC | 31 Dec 2025 | |||
| Satter Muneer A | 7.2% | $36,032,262 | 10,444,134 | Satter Muneer A | 19 Nov 2025 | |||
| FMR LLC | 7.1% | -30% | $51,316,801 | -$4,310,639 | 10,222,470 | -7.7% | FMR LLC | 31 Dec 2025 |
| BlackRock, Inc. | 6.1% | $44,521,150 | 8,868,755 | BlackRock, Inc. | 31 Dec 2025 | |||
| Bain Capital Life Sciences Fund, L.P. | 4.9% | $9,973,231 | 5,249,069 | BCLS I Investco, LP | 31 Dec 2024 | |||
| Point72 Asset Management, L.P. | 0.1% | $181,317 | 95,430 | Point72 Asset Management, L.P. | 31 Mar 2025 |
As of 31 Dec 2025, 167 institutional investors reported holding 136,910,694 shares of Annexon, Inc. - Common Stock (ANNX). This represents 88% of the company’s total 155,837,030 outstanding shares.
Top 25 Institutional Shareholders
The largest institutional shareholders of Annexon, Inc. - Common Stock (ANNX) together control 71% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| FMR LLC | 6.6% | 10,222,470 | -7.7% | 0% | $51,316,800 |
| Redmile Group, LLC | 6.4% | 10,050,644 | +60% | 3.7% | $50,454,233 |
| BVF INC/IL | 5.9% | 9,128,080 | +30% | 1.5% | $45,822,962 |
| BlackRock, Inc. | 5.7% | 8,960,434 | +13% | 0% | $44,981,380 |
| VANGUARD GROUP INC | 5% | 7,753,387 | +33% | 0% | $38,922,003 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | 3.5% | 5,500,000 | +267% | 0.04% | $27,610,000 |
| Bain Capital Life Sciences Investors, LLC | 3.4% | 5,249,069 | 0% | 2% | $26,350,326 |
| Bellevue Group AG | 3.3% | 5,157,290 | 0% | 0.49% | $25,889,596 |
| STATE STREET CORP | 3% | 4,652,185 | +127% | 0% | $23,353,969 |
| AMERIPRISE FINANCIAL INC | 2.8% | 4,348,782 | +98% | 0% | $21,830,887 |
| Woodline Partners LP | 2.6% | 4,000,074 | +52% | 0.08% | $20,080,371 |
| Balyasny Asset Management L.P. | 2.1% | 3,299,256 | +154% | 0.03% | $16,562,265 |
| Longaeva Partners L.P. | 2% | 3,100,000 | 1.9% | $15,562,000 | |
| MAK CAPITAL ONE LLC | 1.9% | 2,958,527 | 2% | $14,851,806 | |
| Nuveen, LLC | 1.9% | 2,915,324 | +327% | 0% | $14,634,927 |
| GEODE CAPITAL MANAGEMENT, LLC | 1.9% | 2,902,896 | +19% | 0% | $14,576,148 |
| MORGAN STANLEY | 1.8% | 2,856,143 | -5.7% | 0% | $14,337,838 |
| MILLENNIUM MANAGEMENT LLC | 1.8% | 2,836,857 | +0.5% | 0.01% | $14,241,022 |
| Opaleye Management Inc. | 1.7% | 2,600,000 | 0% | 1.7% | $13,052,000 |
| Palo Alto Investors LP | 1.5% | 2,384,192 | 1.7% | $11,968,644 | |
| Qube Research & Technologies Ltd | 1.5% | 2,381,479 | +316% | 0.02% | $11,955,025 |
| Tetragon Partners GP Ltd | 1.3% | 2,032,455 | -3.8% | 2.2% | $10,202,924 |
| GOLDMAN SACHS GROUP INC | 1.1% | 1,768,745 | -26% | 0% | $8,879,100 |
| BANK OF AMERICA CORP /DE/ | 1% | 1,605,581 | +24% | 0% | $8,060,016 |
| SPHERA FUNDS MANAGEMENT LTD. | 0.84% | 1,316,212 | -27% | 1.4% | $6,607,384 |
Institutional Holders of Annexon, Inc. - Common Stock (ANNX) across Reporting Periods
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q1 | 20,060,170 | $111,128,533 | +$23,264,313 | $5.54 | 64 |
| 2025 Q4 | 136,910,694 | $687,231,703 | +$183,803,680 | $5.02 | 167 |
| 2025 Q3 | 101,380,733 | $309,219,194 | +$11,142,271 | $3.05 | 143 |
| 2025 Q2 | 99,449,067 | $238,679,312 | +$759,672 | $2.40 | 127 |
| 2025 Q1 | 99,491,910 | $192,036,870 | -$14,234,585 | $1.93 | 146 |
| 2024 Q4 | 111,907,572 | $574,088,227 | +$7,286,342 | $5.13 | 151 |
| 2024 Q3 | 109,990,075 | $651,286,147 | +$12,076,588 | $5.92 | 141 |
| 2024 Q2 | 107,381,777 | $526,166,969 | +$50,550,360 | $4.90 | 139 |
| 2024 Q1 | 94,762,361 | $679,439,424 | +$107,931,991 | $7.17 | 125 |
| 2023 Q4 | 80,514,496 | $365,538,892 | +$125,501,716 | $4.54 | 98 |
| 2023 Q3 | 53,312,574 | $125,814,682 | -$910,472 | $2.36 | 91 |
| 2023 Q2 | 53,372,682 | $187,869,879 | -$1,833,578 | $3.52 | 93 |
| 2023 Q1 | 53,953,057 | $207,583,535 | +$11,598,782 | $3.85 | 98 |
| 2022 Q4 | 47,049,561 | $243,269,266 | +$3,854,655 | $5.17 | 81 |
| 2022 Q3 | 46,270,615 | $285,949,000 | +$49,950,788 | $6.18 | 69 |
| 2022 Q2 | 38,409,280 | $144,864,000 | +$5,360,704 | $3.77 | 74 |
| 2022 Q1 | 38,555,259 | $105,261,060 | -$23,763,559 | $2.73 | 96 |
| 2021 Q4 | 38,766,276 | $445,683,894 | +$6,730,750 | $11.49 | 94 |
| 2021 Q3 | 38,055,922 | $708,635,015 | -$28,821,254 | $18.61 | 81 |
| 2021 Q2 | 38,854,536 | $873,668,672 | +$29,687,677 | $22.51 | 73 |
| 2021 Q1 | 37,426,974 | $1,040,768,344 | +$38,809,119 | $27.84 | 72 |
| 2020 Q4 | 36,208,873 | $904,277,496 | -$17,927,945 | $25.03 | 70 |
| 2020 Q3 | 34,842,574 | $1,039,585,431 | +$1,039,585,431 | $30.23 | 65 |