Annexon, Inc. financial metrics

Professional SEC-based dashboard for profitability, financial health, and growth with transparent scoring logic. Latest period: Q4 2025.

Symbol
ANNX on Nasdaq
Location
Brisbane, CA
Fiscal year end
31 December
Latest financial report
30 Mar 2026

Shareable Research Card

ANNX - Annexon, Inc. Financial Facts

ANNX - Annexon, Inc. has a source-backed company facts page for reviewing reported financial metrics, periods, and linked metric histories.

Start with the latest metric summary, then open metric histories or cross-company rankings to compare the same SEC-backed facts.

Context
Latest metrics period: Q4 2025
Latest reported value
Return On Equity -82%

Based on company facts extracted from SEC 10-Q/10-K XBRL filings where available. Open metric pages to inspect the reported history.

Open stable link Open latest 10-Q/10-K hub Which companies report the highest net income?

Quick Takeaways

  • ANNX - Annexon, Inc. financial facts are built from SEC company filings data.
  • Latest metrics period on this page: Q4 2025.
  • Headline metric: Return On Equity -82%.

What Changed

  • Return On Equity YoY change: <span class="text-green-600">+61%</span>.
  • Most recent SEC facts end date: 31 Dec 2025.

Why This Matters

  • This gives a beginner-friendly first read before you inspect detailed formulas and metric tables.
  • Every metric card links to a deeper SEC-backed history page for verification.

Source Evidence

Based on latest 10-Q/10-K

Based on company facts extracted from SEC 10-Q/10-K XBRL filings where available. Open company facts to inspect the reported metric history.

See Original Filing

Latest SEC snapshot (2025-12-31) highlights Return On Equity -81.9%, Return On Assets -65.9%, and Current Ratio 5.68x.

Compare This Company Through SEC-backed Metrics

Use these links to compare ANNX - Annexon, Inc. against other SEC filers on the same metric, then verify the company history from the paired facts page.

Financial Quality Score

Transparent 0-100 scoring model based on profitability, financial health, and growth factors.

9.0/100

Weak Confidence low

Return On Equity

-82%

Metric score 0.0/100

Return On Assets

-66%

Metric score 0.0/100

Financial Health

Current Ratio
5.68x

Strengths

No strong signals yet.

Watchpoints

Return On Equity, Return On Assets, and Current Ratio

Key metrics snapshot

Return On Equity

-82%

YoY: +61%

Industry median: -43% (n=675)

View history

Return On Assets

-66%

YoY: +54%

Industry median: -47% (n=673)

View history

Current Ratio

5.68x

YoY: -45%

Industry median: 3.39x (n=667)

View history

NetIncomeLoss YoY

-50%

YoY:

Industry median: -0.93% (n=641)

View history

Profitability

Metric Latest value YoY change
Return On Equity -82% +61%
Return On Assets -66% +54%

Financial Health

Metric Latest value YoY change
Current Ratio 5.68x -45%

Growth

Metric Latest value YoY change
NetIncomeLoss YoY -50%

Share Metrics

Metric Latest value YoY change
Common Stock, Shares, Outstanding 149,362,800 +37%
Common Stock, Value, Issued $149,000 +37%
Weighted Average Number of Shares Outstanding, Basic 155,105,832 +13%
Weighted Average Number of Shares Outstanding, Diluted 155,105,832 +13%

Additional Metrics

Metric Latest value YoY change
Research and Development Expense $184,698,000 +55%
General and Administrative Expense $31,709,000 -8.4%
Operating Income (Loss) $216,407,000 -40%
Earnings Per Share, Basic -1.34 -33%
Earnings Per Share, Diluted -1.34 -33%
Cash and Cash Equivalents, at Carrying Value $162,051,000 +227%
Cash, Cash Equivalents, and Short-term Investments $238,300,000 -24%
Assets, Current $242,191,000 -23%
Property, Plant and Equipment, Net $10,617,000 -16%
Operating Lease, Right-of-Use Asset $15,185,000 -9.1%
Other Assets, Noncurrent $8,546,000 +164%
Assets $277,571,000 -21%
Accounts Payable, Current $14,931,000 +43%
Liabilities, Current $42,630,000 +40%
Operating Lease, Liability, Noncurrent $23,293,000 -12%
Liabilities $65,923,000 +16%
Accumulated Other Comprehensive Income (Loss), Net of Tax $29,000 -390%
Retained Earnings (Accumulated Deficit) $917,389,000 -29%
Stockholders' Equity Attributable to Parent $211,648,000 -28%
Liabilities and Equity $277,571,000 -21%
Common Stock, Shares Authorized 300,000,000 0%
Common Stock, Shares, Issued 149,362,800 +37%
Common Stock, Par or Stated Value Per Share 0.001 0%
Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents $163,083,000 +223%
Deferred Tax Assets, Valuation Allowance $224,891,000 +24%
Deferred Tax Assets, Gross $229,246,000 +23%
Operating Lease, Liability $26,201,000 -9.6%
Depreciation $2,200,000 0%
Comprehensive Income (Loss), Net of Tax, Attributable to Parent $206,729,000 -50%
Lessee, Operating Lease, Liability, to be Paid $33,267,000 -13%
Property, Plant and Equipment, Gross $19,962,000 +0.73%
Operating Lease, Liability, Current $2,908,000 +15%
Lessee, Operating Lease, Liability, to be Paid, Year Two $5,425,000 +3.5%
Lessee, Operating Lease, Liability, to be Paid, Year One $5,242,000 +3.5%
Lessee, Operating Lease, Liability, Undiscounted Excess Amount $7,066,000 -25%
Lessee, Operating Lease, Liability, to be Paid, Year Three $5,615,000 +3.5%
Deferred Tax Assets, Operating Loss Carryforwards $133,952,000 +42%
Unrecognized Tax Benefits $9,702,000 +15%
Lessee, Operating Lease, Liability, to be Paid, Year Four $5,812,000 +3.5%
Additional Paid in Capital $1,128,917,000 +12%
Deferred Tax Assets, Net of Valuation Allowance $4,355,000 -13%
Share-based Payment Arrangement, Expense $16,423,000 -15%

How we score

This score is transparent and deterministic. We weight profitability, financial health, and growth metrics, then renormalize weights when SEC data is missing.

Metric Weight V1 threshold
ROIC205% to 20%
ROE158% to 25%
ROA102% to 10%
Operating Margin55% to 25%
Current Ratio121.0x to 2.0x
Quick Ratio80.8x to 1.5x
Debt to Equity100.3x to 2.0x (lower is better)
Revenue YoY10-10% to +20%
Net Income YoY10-10% to +20%

How Calculated (standard_v1)

Metrics are computed with a market-consensus convention designed for cross-portal comparability.

  • TTM Operating Income / TTM Revenues
  • Current Assets / Current Liabilities (latest instant quarter)
  • (Current Assets - Inventory) / Current Liabilities; fallback: (Cash+Short-Term Investments + Accounts Receivable) / Current Liabilities
  • Total Debt / Stockholders Equity (latest instant quarter; shared unit; freshest series)
  • TTM Net Income / Average Equity (current quarter + same quarter previous year) / 2
  • TTM Net Income / Average Assets (current quarter + same quarter previous year) / 2
  • TTM NOPAT / Average Invested Capital, where NOPAT=Operating Income*(1-tax rate), Invested Capital=Equity+Total Debt-Cash & ST Investments
  • TTM Revenues YoY
  • TTM Net Income YoY