Alto Neuroscience, Inc. - Common Stock, par value $0.0001 per share (ANRO)

Q: What does CUSIP 02157Q109 represent in this 13F holders report?

CUSIP 02157Q109 is the security identifier for ANRO - Alto Neuroscience, Inc. - Common Stock, par value $0.0001 per share used to aggregate holder disclosures.

Q: How many institutions held ANRO - Alto Neuroscience, Inc. - Common Stock, par value $0.0001 per share in Q1 2026?

110 institutional investors reported ANRO - Alto Neuroscience, Inc. - Common Stock, par value $0.0001 per share for Q1 2026. Use the holders table for investor-level position and value details.

CUSIP: 02157Q109

Q1 2026 13F Holders as of 31 Mar 2026

Type / Class: Equity / Common Stock, par value $0.0001 per share
Shares outstanding: 31,755,000
Total 13F shares: 26,830,701
Share change: +2,359,630
Total reported value: $602,479,913
Put/Call ratio: 3.4%
Price per share: $22.48
Number of holders: 110
Value change: +$54,953,807
Number of buys: 48
Number of sells: 52

Quarterly Holders Quick Answers

What is CUSIP 02157Q109?
CUSIP 02157Q109 identifies ANRO - Alto Neuroscience, Inc. - Common Stock, par value $0.0001 per share in SEC institutional holdings data.

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Previous quarter: Q4 2025

Recent filing periods for CUSIP 02157Q109:

Q1 2026 Q4 2025 Q3 2025 Q2 2025 Q1 2025 Q4 2024 Q3 2024 Q2 2024

Top shareholders of ANRO - Alto Neuroscience, Inc. - Common Stock, par value $0.0001 per share (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.

Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Holder	Source	Role / Reporting	Ownership %	Shares	Holdings Value	12M Net Δ	As of	Details
Commodore Capital LP	13D/G 13F	Company	9.9%	3,588,180	$77,791,742	+$7,426,527	31 Mar 2026	13D/G 13F
Alpha Wave Global, LP	13F 3/4/5	Company · 10%+ Owner	12%	3,707,757	$65,998,075	—	31 Dec 2025	13F 3/4/5
Point72 Asset Management, L.P.	13F 13D/G	Company · Steven A. Cohen	3.7% from 13D/G	4,432,453 mixed-class rows	$64,883,188	—	31 Dec 2025	13F 13D/G
BlackRock, Inc.	13F 13D/G	Company	2.1% from 13D/G	4,468,395 mixed-class rows	$60,389,247	—	31 Dec 2025	13F 13D/G
Sirenia Capital Management LP	13D/G	—	7.9%	2,591,587	$56,185,606	$0	31 Mar 2026	13D/G
VANGUARD GROUP INC	13F	Company	— mixed-class rows	3,802,680 mixed-class rows	$55,601,013	—	31 Dec 2025	13F
PERCEPTIVE ADVISORS LLC	13D/G 13F	Company	10%	3,249,934	$53,623,911	+$20,798,926	31 Dec 2025	13D/G 13F
ARMISTICE CAPITAL, LLC	13F 13D/G	Company	4.9% from 13D/G	3,236,000 mixed-class rows	$49,168,800	—	31 Dec 2025	13F 13D/G
Vestal Point Capital, LP	13D/G 13F	Company	6.5%	2,064,075	$44,749,146	-$9,125,654	31 Mar 2026	13D/G 13F
SYSTEMATIC FINANCIAL MANAGEMENT LP	13F	Company	6.1%	2,504,864	$32,162,463	—	31 Dec 2025	13F
MILLENNIUM MANAGEMENT LLC	13F	Company	— mixed-class rows	1,472,533 mixed-class rows	$22,032,049	—	31 Dec 2025	13F
Kevin Kotler	13F	Individual	4.1%	1,713,789	$21,997,218	—	31 Dec 2025	13F
FRANKLIN RESOURCES INC	13F	Company	— mixed-class rows	1,167,937 mixed-class rows	$20,549,418	—	31 Dec 2025	13F
STATE STREET CORP	13F	Company	— mixed-class rows	1,403,400 mixed-class rows	$18,667,754	—	31 Dec 2025	13F
Vivo Capital, LLC	13F	Company	3.3%	1,035,551	$18,432,808	—	31 Dec 2025	13F
WEBER CAPITAL MANAGEMENT LLC /ADV	13F	Company	3.4%	1,400,149	$17,977,913	—	31 Dec 2025	13F
GEODE CAPITAL MANAGEMENT, LLC	13F	Company	— mixed-class rows	1,257,333 mixed-class rows	$17,575,396	—	31 Dec 2025	13F
Nuveen, LLC	13F	Company	3.1%	1,295,072	$16,628,724	—	31 Dec 2025	13F
ROYCE & ASSOCIATES LP	13F	Company	3.1%	1,267,451	$16,274,071	—	31 Dec 2025	13F
SEGALL BRYANT & HAMILL, LLC	13F	Company	2.9%	1,198,157	$15,384,336	—	31 Dec 2025	13F
K2 HealthVentures Equity Trust LLC	13D/G	—	2.4%	788,995	$13,018,418	-$13,676,190	31 Dec 2025	13D/G
Bastion Asset Management Inc.	13F	Company	2.7%	1,118,180	$12,885,191	—	31 Dec 2025	13F
RENAISSANCE TECHNOLOGIES LLC	13F	Company	— mixed-class rows	940,482 mixed-class rows	$12,558,888	—	31 Dec 2025	13F
NORTHERN TRUST CORP	13F	Company	— mixed-class rows	779,494 mixed-class rows	$12,361,592	—	31 Dec 2025	13F
DIMENSIONAL FUND ADVISORS LP	13F	Company	— mixed-class rows	947,515 mixed-class rows	$12,321,333	—	31 Dec 2025	13F
72 Investment Holdings, LLC	13F	Company	2.1%	667,778	$11,886,448	—	31 Dec 2025	13F
UBS Group AG	13F	Company	— mixed-class rows	748,567 mixed-class rows	$9,703,306	—	31 Dec 2025	13F
ARROWSTREET CAPITAL, LIMITED PARTNERSHIP	13F	Company	1.8%	752,941	$9,667,762	—	31 Dec 2025	13F
Ikarian Capital, LLC	13F	Company	1.6%	515,000	$9,167,001	—	31 Dec 2025	13F
PARADIGM CAPITAL MANAGEMENT INC/NY	13F	Company	1.6%	678,200	$8,708,088	—	31 Dec 2025	13F
ALKEON CAPITAL MANAGEMENT LLC	13F	Company	1.5%	477,101	$8,492,398	—	31 Dec 2025	13F
Phocas Financial Corp.	13F	Company	1.5%	606,273	$7,784,545	—	31 Dec 2025	13F
Pier Capital, LLC	13F	Company	1.4%	571,855	$7,342,618	—	31 Dec 2025	13F
JANE STREET GROUP, LLC	13F	Company	— mixed-class rows	494,941 mixed-class rows	$7,317,485	—	31 Dec 2025	13F
MARSHALL WACE, LLP	13F	Company	— mixed-class rows	477,797 mixed-class rows	$7,092,736	—	31 Dec 2025	13F
GOLDMAN SACHS GROUP INC	13F	Company	— mixed-class rows	472,708 mixed-class rows	$6,844,912	—	31 Dec 2025	13F
Integral Health Asset Management, LLC	13F	Company	1.2%	375,000	$6,675,000	—	31 Dec 2025	13F
TWO SIGMA INVESTMENTS, LP	13F	Company	— mixed-class rows	445,177 mixed-class rows	$6,412,045	—	31 Dec 2025	13F
DRIEHAUS CAPITAL MANAGEMENT LLC	13F	Company	1.1%	336,762	$5,994,364	—	31 Dec 2025	13F
TWO SIGMA ADVISERS, LP	13F	Company	— mixed-class rows	390,101 mixed-class rows	$5,802,993	—	31 Dec 2025	13F
Manatuck Hill Partners, LLC	13F	Company	1%	425,000	$5,457,000	—	31 Dec 2025	13F
Connor, Clark & Lunn Investment Management Ltd.	13F	Company	0.96%	398,172	$5,112,528	—	31 Dec 2025	13F
Qube Research & Technologies Ltd	13F	Company	— mixed-class rows	342,088 mixed-class rows	$4,951,859	—	31 Dec 2025	13F
ESSEX INVESTMENT MANAGEMENT CO LLC	13F	Company	0.87%	360,544	$4,629,385	—	31 Dec 2025	13F
MORGAN STANLEY	13F	Company	— mixed-class rows	334,685 mixed-class rows	$4,622,639	—	31 Dec 2025	13F
CHARLES SCHWAB INVESTMENT MANAGEMENT INC	13F	Company	— mixed-class rows	349,970 mixed-class rows	$4,578,252	—	31 Dec 2025	13F
Peapod Lane Capital LLC	13F	Company	0.8%	253,992	$4,521,058	—	31 Dec 2025	13F
AWM Investment Company, Inc.	13F	Company	0.71%	225,000	$4,005,000	—	31 Dec 2025	13F
Spruce Street Capital LP	13F	Company	0.7%	222,844	$3,966,623	—	31 Dec 2025	13F
ACADIAN ASSET MANAGEMENT LLC	13F	Company	— mixed-class rows	247,823 mixed-class rows	$3,460,000	—	31 Dec 2025	13F

Institutional Holders of Alto Neuroscience, Inc. - Common Stock, par value $0.0001 per share (ANRO) as of Q1 2026

As of 31 Mar 2026, Alto Neuroscience, Inc. - Common Stock, par value $0.0001 per share (ANRO) was held by 110 institutional shareholders that filed Form 13F with the SEC. Together, they reported ownership of 26,830,701 shares. The largest 10 holders included Alpha Wave Global, LP, Commodore Capital LP, Vestal Point Capital, LP, PERCEPTIVE ADVISORS LLC, Spruce Street Capital LP, VANGUARD CAPITAL MANAGEMENT LLC, FRANKLIN RESOURCES INC, Vivo Capital, LLC, ARMISTICE CAPITAL, LLC, and MILLENNIUM MANAGEMENT LLC. This page lists 110 institutional shareholders reporting positions in this security for the Q1 2026 filing period.

Investor	Option	Weight %	Change %	Value $	* Price	Shares	Share Change	Activity	Report Period

Compare Q1 2026 vs Q4 2025 Across Filers

Q4 2025 holders

Q1 2026 holders

110

Holder diff

Investor	Q4 2025 Shares	Q1 2026 Shares	Share Diff	Share Chg %	Q4 2025 Value $	Q1 2026 Value $	Value Diff $	Value Chg %

Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).

Quarterly Holders Trend

Quarterly Value Trend

Quarterly Shares Trend

* Reported Price is the price of the security as of the portfolio date. This value is significant in that it is the last known price at which the security was still held.
An asterisk sign (*) next to the price indicates that the price is likely invalid.