Latest Period
Q4 2025
Security Snapshot
ACTUATE THERAPEUTICS, INC. - Common Stock, par value $0.000001 per share (ACTU) Institutional Ownership
CUSIP: 005083100
13F Institutional Holders and Ownership History from Q3 2024 to Q1 2026
Institutions Reporting
44
Shares (Excl. Options)
13,110,237
Price
$6.12
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- Type / Class
- Equity / Common Stock, par value $0.000001 per share
- Symbol
- ACTU on Nasdaq
- Shares outstanding
- 23,561,857
- Price per share
- $1.82
- All holders as of 31 Dec 2025
- Q4 2025
- Total 13F shares
- 13,110,237
- Total reported value
- $80,234,480
- % of total 13F portfolios
- 0%
- Share change
- +1,089,796
- Value change
- +$6,660,093
- Number of holders
- 44
- Price from insider filings
- $1.82
Reported Shares, Excluding Options vs Price
Reported Value, Excluding Options
Total Investors
Quick Takeaways
- ACTU - ACTUATE THERAPEUTICS, INC. - Common Stock, par value $0.000001 per share is tracked under CUSIP 005083100.
- 44 institutions reported positions in Q4 2025.
- 2 significant owners is listed from Schedule 13D/13G reporting.
What Changed
- Holder count moved from 44 to 36 between Q4 2025 and Q1 2026.
- Reported value moved from $80,234,480 to $31,314,404.
Why This Matters
- You can quickly see who holds this security, then open quarter and manager detail pages for full evidence.
- 13F and Schedule 13D/13G sections are kept together so you can cross-check institutional and beneficial ownership context.
Source Evidence
Source: SEC Form 13F
Open SEC Evidence
Latest holder context comes from 44 institutions filings for Q4 2025.
Investment Quick Answers
What is CUSIP 005083100?
CUSIP 005083100 identifies ACTU - ACTUATE THERAPEUTICS, INC. - Common Stock, par value $0.000001 per share in SEC 13F datasets.
Where can I see the latest institutional holders?
Review the Q4 2025 holders report and the ownership history table below.
Next ownership checks
Use the next link that matches the question you still need to answer about this security.
- Latest 13F filings when you want to inspect fresh institutional portfolio moves.
- Latest Schedule 13D/13G reports when you need large-owner changes outside the 13F cycle.
- All institutional ownership pages to compare this security with other holder-history pages.
Recent Quarterly Holder Reports
Open recent reporting periods for CUSIP 005083100:
Significant Owners of ACTUATE THERAPEUTICS, INC. - Common Stock, par value $0.000001 per share (ACTU) based on Schedule 13D/G filings
| Filer | Ownership | Change % | Holdings Value | Net Change | Nb Shares | Change % | Reporting Name | Report Period |
|---|---|---|---|---|---|---|---|---|
| BIOS Fund I, LP | 50% | -2.9% | $112,734,207 | +$1,733,259 | 10,267,232 | +1.6% | AARON G.L. FLETCHER | 27 Jun 2025 |
| Voss Capital, LP | 7.7% | +48% | $5,013,716 | +$1,620,812 | 1,814,263 | +48% | Voss Capital, LP | 31 Mar 2026 |
As of 31 Dec 2025, 44 institutional investors reported holding 13,110,237 shares of ACTUATE THERAPEUTICS, INC. - Common Stock, par value $0.000001 per share (ACTU). This represents 56% of the company’s total 23,561,857 outstanding shares.
Top 25 Institutional Shareholders
The largest institutional shareholders of ACTUATE THERAPEUTICS, INC. - Common Stock, par value $0.000001 per share (ACTU) together control 55% of the company’s outstanding shares — a level of ownership often associated with strong institutional conviction and long‑term capital commitment.
| Institution | Ownership % | Shares Held | Share Change % | Portfolio % | Holdings Value |
|---|---|---|---|---|---|
| BIOS Capital Management, LP | 43% | 10,049,996 | 0% | 74% | $61,505,976 |
| Voss Capital, LP | 5.5% | 1,300,000 | +45% | 0.42% | $7,956,000 |
| VANGUARD GROUP INC | 2.2% | 529,111 | +67% | 0% | $3,238,159 |
| BlackRock, Inc. | 1.8% | 432,041 | +53% | 0% | $2,644,091 |
| GEODE CAPITAL MANAGEMENT, LLC | 0.88% | 207,744 | +43% | 0% | $1,271,393 |
| NORTHERN TRUST CORP | 0.43% | 101,423 | +19% | 0% | $620,709 |
| Texas Capital Bank Wealth Management Services Inc | 0.4% | 94,592 | 0.03% | $578,903 | |
| STATE STREET CORP | 0.24% | 56,290 | +13% | 0% | $344,495 |
| ROYAL BANK OF CANADA | 0.15% | 35,187 | +173% | 0% | $215,000 |
| BRIDGEWAY CAPITAL MANAGEMENT, LLC | 0.13% | 30,982 | 0% | $189,610 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 0.1% | 23,841 | +61% | 0% | $145,907 |
| Rock Creek Group, LP | 0.09% | 21,759 | 0.02% | $133,165 | |
| WELLS FARGO & COMPANY/MN | 0.09% | 20,146 | +49% | 0% | $123,294 |
| SFMG, LLC | 0.08% | 20,000 | +18% | 0.01% | $122,400 |
| Gleason Group, Inc. | 0.08% | 19,028 | 0% | 0.01% | $116,451 |
| NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 0.08% | 18,518 | -4.1% | 0% | $113,330 |
| JANE STREET GROUP, LLC | 0.07% | 16,625 | 0% | $101,745 | |
| BARCLAYS PLC | 0.06% | 14,946 | +69% | 0% | $91,470 |
| MORGAN STANLEY | 0.06% | 13,119 | +72% | 0% | $80,289 |
| LPL Financial LLC | 0.06% | 12,965 | -20% | 0% | $79,346 |
| Bank of New York Mellon Corp | 0.05% | 12,565 | 0% | $76,898 | |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | 0.04% | 10,253 | 0% | $62,748 | |
| RHUMBLINE ADVISERS | 0.04% | 9,534 | +8.7% | 0% | $58,343 |
| DEUTSCHE BANK AG\ | 0.04% | 9,309 | +640% | 0% | $56,971 |
| BANK OF AMERICA CORP /DE/ | 0.04% | 9,061 | +86% | 0% | $55,454 |
Institutional Holders of ACTUATE THERAPEUTICS, INC. - Common Stock, par value $0.000001 per share (ACTU) across Reporting Periods
| Period | Reported Shares, Excl. Options | Value, Excl. Options | Value Change | Price (Median) | Investors |
|---|---|---|---|---|---|
| 2026 Q1 | 11,429,251 | $31,314,404 | +$347,799 | $2.74 | 36 |
| 2025 Q4 | 13,110,237 | $80,234,480 | +$6,660,093 | $6.12 | 44 |
| 2025 Q3 | 12,026,097 | $80,455,749 | +$5,410,880 | $6.69 | 42 |
| 2025 Q2 | 11,217,203 | $68,541,901 | +$4,868,272 | $6.11 | 38 |
| 2025 Q1 | 10,401,592 | $70,445,498 | +$1,934,199 | $6.77 | 25 |
| 2024 Q4 | 10,116,136 | $80,524,037 | -$1,087,916 | $7.96 | 19 |
| 2024 Q3 | 382,167 | $2,847,155 | +$2,847,155 | $7.45 | 10 |