Filing Manager
BIOS Fund I, LP
Reporting Manager
AARON G.L. FLETCHER
Symbol
ACTU
Shares outstanding
20,616,932 shares
Disclosed Ownership
10,267,232 shares
Ownership
49.8%
Form type
SCHEDULE 13D/A
Filing time
30 Jun 2025, 12:08:12 UTC
Date of event
27 Jun 2025
Previous filing
27 May 2025

Reporting Managers (24)

Name Ownership Shares Owned sole voting power shared voting power Signature Title CIK
BIOS FUND I, LP 2.6% 525,797 0 525,797 John Fucci Attorney-in-Fact 0001697316
BIOS FUND I QP, LP 1.5% 307,538 0 307,538 John Fucci Attorney-in-Fact 0001700297
BIOS FUND II, LP 1.5% 308,211 0 308,211 John Fucci Attorney-in-Fact 0001714576
BIOS FUND II QP, LP 4.9% 1,006,788 0 1,006,788 John Fucci Attorney-in-Fact 0001716869
BIOS FUND II NT, LP 0.7% 134,776 0 134,776 John Fucci Attorney-in-Fact 0001728851
BIOS FUND III, LP 1.9% 383,791 0 383,791 John Fucci Attorney-in-Fact 0001791917
BIOS FUND III QP, LP 12.3% 2,506,667 0 2,506,667 John Fucci Attorney-in-Fact 0001791916
BIOS FUND III NT, LP 2% 404,814 0 404,814 John Fucci Attorney-in-Fact 0001791910
BP DIRECTORS, LP 0.6% 116,801 0 116,801 John Fucci Attorney-in-Fact 0001813311
BIOS ACTUATE CO-INVEST I, LP 1.5% 300,749 0 300,749 John Fucci Attorney-in-Fact 0001771378
BIOS ACTUATE CO-INVEST II, LP 10.2% 2,094,650 0 2,094,650 John Fucci Attorney-in-Fact 0001825398
BIOS ACTUATE CO-INVEST III, LP 2.8% 573,394 0 573,394 John Fucci Attorney-in-Fact 0001956704
BIOS CLINICAL OPPORTUNITY FUND, LP 6.2% 1,259,427 0 1,259,427 John Fucci Attorney-in-Fact 0001988639
BIOS 2024 CO-INVEST, LP 1.3% 267,856 0 267,856 John Fucci Attorney-in-Fact 0002028708
BIOS EQUITY PARTNERS, LP 4.6% 950,136 0 950,136 John Fucci Attorney-in-Fact 0001813314
BIOS EQUITY PARTNERS II, LP 8.5% 1,750,524 0 1,750,524 John Fucci Attorney-in-Fact 0001813313
BIOS EQUITY PARTNERS III, LP 29.2% 5,963,316 0 5,963,316 John Fucci Attorney-in-Fact 0001831976
BIOS EQUITY COF, LP 7.4% 1,527,283 0 1,527,283 John Fucci Attorney-in-Fact 0002000747
CAVU MANAGEMENT, LP 42.2% 8,663,976 0 8,663,976 John Fucci Attorney-in-Fact 0001813270
BIOS CAPITAL MANAGEMENT, LP 49.5% 10,191,259 0 10,191,259 John Fucci Attorney-in-Fact 0001813845
CAVU ADVISORS, LLC 42.2% 8,663,976 0 8,663,976 John Fucci Attorney-in-Fact 0001813310
BIOS ADVISORS GP, LLC 49.5% 10,191,259 0 10,191,259 John Fucci Attorney-in-Fact 0001813844
LESLIE W. KREIS 42.6% 8,733,351 69,375 8,663,976 John Fucci Attorney-in-Fact 0001813316
AARON G.L. FLETCHER 49.8% 10,267,232 60,973 10,048,403 John Fucci Attorney-in-Fact 0001789490