Security key
004225108
CUSIP: 004225108
Security key
004225108
Report period
Q3 2022
Institutions
213
Top holders
10
Broader feeds
Reporting periods
Recent filing periods:
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| BAKER BROS. ADVISORS LP |
13F
|
Company |
25%
|
41,923,486
|
$590,702,000 | — | 30 Jun 2022 | |
| VANGUARD GROUP INC |
13F
|
Company |
7.3%
|
12,400,593
|
$174,724,000 | — | 30 Jun 2022 | |
| FMR LLC |
13F
|
Company |
7.3%
|
12,398,957
|
$174,701,000 | — | 30 Jun 2022 | |
| BlackRock Finance, Inc. |
13F
|
Company |
5.7%
|
9,741,314
|
$137,256,000 | — | 30 Jun 2022 | |
| STATE STREET CORP |
13F
|
Company |
3.9%
|
6,593,950
|
$92,909,000 | — | 30 Jun 2022 | |
| EcoR1 Capital, LLC |
13F
|
Company |
3.5%
|
5,991,479
|
$84,420,000 | — | 30 Jun 2022 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
|
Company |
2.8%
|
4,693,715
|
$66,134,000 | — | 30 Jun 2022 | |
| D. E. Shaw & Co., Inc. |
13F
|
Company |
2.7%
|
4,686,665
|
$66,035,000 | — | 30 Jun 2022 | |
| RTW INVESTMENTS, LP |
13F
|
Company |
2.5%
|
4,224,109
|
$59,518,000 | — | 30 Jun 2022 | |
| MORGAN STANLEY |
13F
|
Company |
1.8%
|
3,120,072
|
$43,961,000 | — | 30 Jun 2022 | |
| FIRST TRUST ADVISORS LP |
13F
|
Company |
1.3%
|
2,171,242
|
$30,593,000 | — | 30 Jun 2022 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
1.3%
|
2,160,984
|
$30,448,000 | — | 30 Jun 2022 | |
| JPMORGAN CHASE & CO |
13F
|
Company |
1.1%
|
1,906,720
|
$26,866,000 | — | 30 Jun 2022 | |
| Deep Track Capital, LP |
13F
|
Company |
1%
|
1,733,130
|
$24,420,000 | — | 30 Jun 2022 | |
| Palo Alto Investors LP |
13F
|
Company |
0.98%
|
1,678,196
|
$23,646,000 | — | 30 Jun 2022 | |
| NORGES BANK |
13F
|
Company |
0.98%
|
1,665,263
|
$23,463,556 | — | 30 Jun 2022 | |
| FRED ALGER MANAGEMENT, LLC |
13F
|
Company |
0.95%
|
1,621,768
|
$22,851,000 | — | 30 Jun 2022 | |
| Boxer Capital, LLC |
13F
|
Company |
0.74%
|
1,263,930
|
$17,809,000 | — | 30 Jun 2022 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.66%
|
1,130,787
|
$15,933,000 | — | 30 Jun 2022 | |
| Nuveen Asset Management, LLC |
13F
|
Company |
0.64%
|
1,096,202
|
$15,446,000 | — | 30 Jun 2022 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
0.62%
|
1,057,494
|
$14,900,000 | — | 30 Jun 2022 | |
| VOLORIDGE INVESTMENT MANAGEMENT, LLC |
13F
|
Company |
0.61%
|
1,042,255
|
$14,685,000 | — | 30 Jun 2022 | |
| AMERIPRISE FINANCIAL INC |
13F
|
Company |
0.55%
|
945,060
|
$13,319,000 | — | 30 Jun 2022 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.54%
|
917,161
|
$12,923,000 | — | 30 Jun 2022 | |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE |
13F
|
Company |
0.53%
|
905,013
|
$12,762,593 | — | 30 Jun 2022 | |
| EMERALD ADVISERS, LLC |
13F
|
Company |
0.5%
|
860,749
|
$12,128,000 | — | 30 Jun 2022 | |
| MILLENNIUM MANAGEMENT LLC |
13F
|
Company |
0.5%
|
854,277
|
$12,037,000 | — | 30 Jun 2022 | |
| PICTET ASSET MANAGEMENT SA |
13F
|
Company |
0.5%
|
847,964
|
$11,948,000 | — | 30 Jun 2022 | |
| EMERALD MUTUAL FUND ADVISERS TRUST |
13F
|
Company |
0.45%
|
766,971
|
$10,807,000 | — | 30 Jun 2022 | |
| WELLINGTON MANAGEMENT GROUP LLP |
13F
|
Company |
0.45%
|
763,591
|
$10,759,000 | — | 30 Jun 2022 | |
| Fairmount Funds Management LLC |
13F
|
Company |
0.44%
|
751,804
|
$10,593,000 | — | 30 Jun 2022 | |
| Finepoint Capital LP |
13F
|
Company |
0.41%
|
707,200
|
$9,964,000 | — | 30 Jun 2022 | |
| Logos Global Management LP |
13F
|
Company |
0.38%
|
650,000
|
$9,159,000 | — | 30 Jun 2022 | |
| PANAGORA ASSET MANAGEMENT INC |
13F
|
Company |
0.38%
|
646,767
|
$9,113,000 | — | 30 Jun 2022 | |
| NORDEA INVESTMENT MANAGEMENT AB |
13F
|
Company |
0.37%
|
630,080
|
$8,890,000 | — | 30 Jun 2022 | |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC |
13F
|
Company |
0.36%
|
614,537
|
$8,658,826 | — | 30 Jun 2022 | |
| Bain Capital Life Sciences Investors, LLC |
13F
|
Company |
0.35%
|
600,523
|
$8,461,000 | — | 30 Jun 2022 | |
| FRONTIER CAPITAL MANAGEMENT CO LLC |
13F
|
Company |
0.33%
|
566,323
|
$7,979,000 | — | 30 Jun 2022 | |
| RICE HALL JAMES & ASSOCIATES, LLC |
13F
|
Company |
0.32%
|
543,528
|
$7,658,000 | — | 30 Jun 2022 | |
| Bank of New York Mellon Corp |
13F
|
Company |
0.29%
|
494,809
|
$6,973,000 | — | 30 Jun 2022 | |
| Squarepoint Ops LLC |
13F
|
Company |
0.29%
|
494,702
|
$6,970,000 | — | 30 Jun 2022 | |
| DIMENSIONAL FUND ADVISORS LP |
13F
|
Company |
0.29%
|
492,928
|
$6,946,000 | — | 30 Jun 2022 | |
| Invesco Ltd. |
13F
|
Company |
0.26%
|
449,694
|
$6,336,000 | — | 30 Jun 2022 | |
| Rockefeller Capital Management L.P. |
13F
|
Company |
0.26%
|
435,235
|
$6,132,000 | — | 30 Jun 2022 | |
| BANK OF AMERICA CORP /DE/ |
13F
|
Company |
0.23%
|
390,766
|
$5,506,000 | — | 30 Jun 2022 | |
| PFM Health Sciences, LP |
13F
|
Company |
0.23%
|
384,995
|
$5,425,000 | — | 30 Jun 2022 | |
| VOYA INVESTMENT MANAGEMENT LLC |
13F
|
Company |
0.19%
|
320,926
|
$4,522,000 | — | 30 Jun 2022 | |
| Artisan Partners Limited Partnership |
13F
|
Company |
0.19%
|
316,293
|
$4,457,000 | — | 30 Jun 2022 | |
| CITADEL ADVISORS LLC |
13F
|
Company |
0.18%
|
299,297
|
$4,217,000 | — | 30 Jun 2022 | |
| Swiss National Bank |
13F
|
Company |
0.17%
|
285,104
|
$4,017,000 | — | 30 Jun 2022 |
| Investor | Option | Weight % | Change % | Value $ | * Price | Shares | Share Change | Activity | Report Period |
|---|
| Investor | Q2 2022 Shares | Q3 2022 Shares | Share Diff | Share Chg % | Q2 2022 Value $ | Q3 2022 Value $ | Value Diff $ | Value Chg % |
|---|
Trend: ostatnie 8 kwartałów (+ wybrane okresy porównania).