Quick Takeaways
- NUVL - Nuvalent, Inc. has 23 insiders with reported activity on this page.
- Net insider value flow over the last year: -$144,587,605.
- Recent transaction rows are available for direct filing-level review.
Insider Transactions Reported by 23 Insiders of Nuvalent, Inc.
- Symbol
- NUVL on Nasdaq
- Location
- Cambridge, MA
What Changed
- Buy value: ; sell value: $144,587,605.
- Net share flow: -1,545,356.
Why This Matters
- This page gives a plain-language issuer insider context before you inspect transaction-level evidence.
- Use the filing links below to verify timestamps, codes, and ownership impacts directly from SEC forms.
Source Evidence
Filed on Form 4
See Original Filing
Issuer insider activity is sourced from SEC Forms 3, 4, and 5.
Insider trading overview
Last 12 monthsNet insider flow leans to selling over the last 12 months. Net value: -$144,587,605.
Buys
$0
Shares: 0
Insiders: 0
Sells
$144,587,605
Shares: 1,545,356
Insiders: 8
Net
-$144,587,605
Shares: -1,545,356
Insiders: -8
| Window (months) | Buy shares | Sell shares | Buy $ | Sell $ | Net $ |
|---|---|---|---|---|---|
| 0-3 | 0 | 162,257 | $0 | $16,293,765 | -$16,293,765 |
| 3-6 | 0 | 922,683 | $0 | $89,257,339 | -$89,257,339 |
| 6-9 | 0 | 308,771 | $0 | $27,173,920 | -$27,173,920 |
| 9-12 | 0 | 151,645 | $0 | $11,862,581 | -$11,862,581 |
Nuvalent, Inc. executives and other stock owners filed with the SEC include:
| Name | Relationship | Holdings Value | Past Year Net Change | Change % | Valuation | Report Date |
|---|---|---|---|---|---|---|
| James E. Flynn | Director, Director by Deputization, 10%+ Owner | $1,639,268,060 | -$70,874,975 | -4.1% | Mixed | 24 Nov 2025 |
| Matthew Shair | Director | $174,338,383 | -$6,835,738 | -3.8% | Filing P/S | 24 Nov 2025 |
| Andrew A. F. Hack | Director | $127,579,408 | Mixed | 11 Dec 2024 | ||
| Wellington Biomedical Innovation Master Investors (Cayman) I L.P. | 10%+ Owner | $68,348,670 | Mixed | 02 Aug 2021 | ||
| DEERFIELD PARTNERS, L.P. | Director, Director by Deputization, 10%+ Owner | $49,491,000 | Mixed | 03 Nov 2022 | ||
| James Richard Porter | President and CEO, Director | $34,307,222 | -$21,547,172 | -39% | Filing P/S | 06 Apr 2026 |
| Alexandra Balcom | Chief Financial Officer | $9,081,893 | -$18,225,006 | -67% | Filing P/S | 01 Apr 2026 |
| Christopher Durant Turner | Chief Medical Officer | $7,305,924 | -$721,320 | -9% | Mixed | 05 Jan 2026 |
| Henry E. Pelish | Chief Scientific Officer | $6,888,420 | -$8,639,341 | -56% | Filing P/S | 09 Apr 2026 |
| Deborah Ann Miller | Chief Legal Officer | $5,931,197 | -$12,260,009 | -67% | Filing P/S | 26 Mar 2026 |
| Darlene Noci | Chief Development Officer | $5,703,021 | -$5,484,044 | -49% | Filing P/S | 30 Mar 2026 |
| Benjamin Lane | Chief Technical Operations Officer | $5,066,517 | Mixed | 01 Apr 2026 | ||
| Grant C. Bogle | Director | $437,121 | Mixed | 18 Jun 2025 | ||
| Joseph Pearlberg | Director | $384,714 | Mixed | 18 Jun 2025 | ||
| Sapna Srivastava | Director | $384,714 | Mixed | 18 Jun 2025 | ||
| Michael L. Meyers | Director | $384,714 | Mixed | 18 Jun 2025 | ||
| Anna Protopapas | Director | $384,714 | Mixed | 18 Jun 2025 | ||
| Cameron Wheeler | Director | $384,714 | Mixed | 18 Jun 2025 | ||
| Christy J. Oliger | Director | $296,871 | Mixed | 18 Jun 2025 | ||
| Ron Squarer | Director | $240,180 | Mixed | 10 Dec 2025 | ||
| Emily Conley | Director | $213,145 | Filing P/S | 23 Aug 2024 | ||
| Dwight Gary Gilliland | Director | $205,743 | Mixed | 12 Jun 2024 | ||
| Robert Bowers Jackson | Director | Mixed | 28 Jul 2021 |
Top shareholders of Nuvalent, Inc. (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| James E. Flynn |
13D/G
3/4/5
|
Deerfield Management Company, L.P. · Director, Director by Deputization, 10%+ Owner |
24%
|
22,852,280
|
$2,238,152,303 | -$71,496,004 | 31 Dec 2025 | |
| DEERFIELD MANAGEMENT COMPANY, L.P. |
13F
|
Company |
18%
|
17,248,450
|
$1,735,021,586 | — | 31 Dec 2025 | |
| FMR LLC |
13F
|
Company |
11%
|
10,852,884
|
$1,091,691,628 | — | 31 Dec 2025 | |
| Paradigm Biocapital Advisors LP |
13F
|
Company |
5.6%
|
5,269,433
|
$530,052,265 | — | 31 Dec 2025 | |
| VANGUARD GROUP INC |
13F
13D/G
|
Company · The Vanguard Group |
6.8%
from 13D/G
|
5,244,271
|
$527,521,219 | — | 31 Dec 2025 | |
| BlackRock, Inc. |
13F
13D/G
|
Company |
5%
from 13D/G
|
4,805,261
|
$483,361,203 | — | 31 Dec 2025 | |
| WELLINGTON MANAGEMENT GROUP LLP |
13F
|
Company |
2.6%
|
2,461,823
|
$247,634,775 | — | 31 Dec 2025 | |
| JPMORGAN CHASE & CO |
13F
|
Company |
2.3%
|
2,205,251
|
$221,826,288 | — | 31 Dec 2025 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
|
Company |
2.3%
|
2,146,938
|
$215,962,000 | — | 31 Dec 2025 | |
| RA CAPITAL MANAGEMENT, L.P. |
13F
|
Company |
2%
|
1,880,057
|
$189,114,934 | — | 31 Dec 2025 | |
| STATE STREET CORP |
13F
|
Company |
2%
|
1,864,675
|
$187,567,658 | — | 31 Dec 2025 | |
| Matthew Shair |
3/4/5
|
Director |
—
mixed-class rows
|
1,583,013
mixed-class rows
|
$174,338,383 | -$6,835,738 | 24 Nov 2025 | |
| PERCEPTIVE ADVISORS LLC |
13F
|
Company |
1.8%
|
1,665,105
|
$167,492,912 | — | 31 Dec 2025 | |
| Polar Capital Holdings Plc |
13F
|
Company |
1.6%
|
1,536,859
|
$154,592,647 | — | 31 Dec 2025 | |
| JANUS HENDERSON GROUP PLC |
13F
|
Company |
1.6%
|
1,499,574
|
$150,822,342 | — | 31 Dec 2025 | |
| T. Rowe Price Investment Management, Inc. |
13F
|
Company |
1.4%
|
1,319,963
|
$132,776,000 | — | 31 Dec 2025 | |
| Andrew A. F. Hack |
3/4/5
|
Director |
—
mixed-class rows
|
1,453,555
mixed-class rows
|
$127,579,408 | — | 11 Dec 2024 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
1.3%
|
1,238,234
|
$124,575,027 | — | 31 Dec 2025 | |
| Bellevue Group AG |
13F
|
Company |
1.1%
|
1,037,468
|
$104,358,906 | — | 31 Dec 2025 | |
| BRAIDWELL LP |
13F
|
Company |
0.87%
|
821,406
|
$82,625,230 | — | 31 Dec 2025 | |
| ALLIANCEBERNSTEIN L.P. |
13F
|
Company |
0.83%
|
785,445
|
$79,007,913 | — | 31 Dec 2025 | |
| Fairmount Funds Management LLC |
13F
|
Company |
0.77%
|
727,563
|
$73,185,562 | — | 31 Dec 2025 | |
| Wellington Biomedical Innovation Master Investors (Cayman) I L.P. |
3/4/5
|
10%+ Owner |
—
class O/S missing
|
897,671
|
$68,348,670 | — | 02 Aug 2021 | |
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
13F
|
Company |
0.68%
|
643,000
|
$64,679,370 | — | 31 Dec 2025 | |
| Woodline Partners LP |
13F
|
Company |
0.65%
|
610,459
|
$61,406,071 | — | 31 Dec 2025 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
0.63%
|
594,459
|
$59,796,631 | — | 31 Dec 2025 | |
| NORGES BANK |
13F
|
Company |
0.61%
|
574,242
|
$57,763,003 | — | 31 Dec 2025 | |
| AMERIPRISE FINANCIAL INC |
13F
|
Company |
0.6%
|
564,298
|
$56,762,904 | — | 31 Dec 2025 | |
| Commodore Capital LP |
13F
|
Company |
0.58%
|
550,000
|
$55,324,500 | — | 31 Dec 2025 | |
| DEERFIELD PARTNERS, L.P. |
3/4/5
|
Director, Director by Deputization, 10%+ Owner |
—
class O/S missing
|
650,000
|
$49,491,000 | — | 03 Nov 2022 | |
| DRIEHAUS CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.51%
|
483,504
|
$48,635,667 | — | 31 Dec 2025 | |
| Hood River Capital Management LLC |
13F
|
Company |
0.5%
|
475,440
|
$47,824,510 | — | 31 Dec 2025 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.48%
|
453,311
|
$45,598,553 | — | 31 Dec 2025 | |
| Invesco Ltd. |
13F
|
Company |
0.47%
|
439,300
|
$44,189,188 | — | 31 Dec 2025 | |
| FRANKLIN RESOURCES INC |
13F
|
Company |
0.44%
|
411,354
|
$41,378,099 | — | 31 Dec 2025 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.43%
|
410,450
|
$41,287,165 | — | 31 Dec 2025 | |
| UBS Group AG |
13F
|
Company |
0.42%
|
399,053
|
$40,140,741 | — | 31 Dec 2025 | |
| AMERICAN CENTURY COMPANIES INC |
13F
|
Company |
0.4%
|
374,232
|
$37,644,117 | — | 31 Dec 2025 | |
| First Turn Management, LLC |
13F
|
Company |
0.39%
|
368,697
|
$37,087,231 | — | 31 Dec 2025 | |
| S.c.a. Candriam |
13F
|
Individual |
0.38%
|
358,013
|
$36,014,061 | — | 31 Dec 2025 | |
| Pictet Asset Management Holding SA |
13F
|
Company |
0.38%
|
355,681
|
$35,777,952 | — | 31 Dec 2025 | |
| James Richard Porter |
3/4/5
|
President and CEO, Director |
—
mixed-class rows
|
456,373
mixed-class rows
|
$34,307,222 | -$21,547,172 | 06 Apr 2026 | |
| Affinity Asset Advisors, LLC |
13F
|
Company |
0.34%
|
322,633
|
$32,453,653 | — | 31 Dec 2025 | |
| SILVERARC CAPITAL MANAGEMENT, LLC |
13F
|
Company |
0.33%
|
311,430
|
$31,326,744 | — | 31 Dec 2025 | |
| Tri Locum Partners LP |
13F
|
Company |
0.33%
|
307,371
|
$30,918,449 | — | 31 Dec 2025 | |
| ArrowMark Colorado Holdings LLC |
13F
|
Company |
0.31%
|
296,029
|
$29,777,557 | — | 31 Dec 2025 | |
| LORD, ABBETT & CO. LLC |
13F
|
Company |
0.3%
|
281,215
|
$28,287,000 | — | 31 Dec 2025 | |
| FRONTIER CAPITAL MANAGEMENT CO LLC |
13F
|
Company |
0.29%
|
270,470
|
$27,206,577 | — | 31 Dec 2025 | |
| Defilade Capital Management, L.P. |
13F
|
Company |
0.29%
|
269,043
|
$27,063,035 | — | 31 Dec 2025 | |
| MORGAN STANLEY |
13F
|
Company |
0.28%
|
267,389
|
$26,896,696 | — | 31 Dec 2025 |
Recent Insider Transactions by Companies or Individuals for Nuvalent, Inc.
Showing up to 300 most recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | Value $ | * Price $ | Shares | Shares Owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| Henry E. Pelish | NUVL | Class A Common Stock | Sale | -4.5% | $323,164 | $104.48 | -3,093 | 65,604 | 09 Apr 2026 | Direct |
| Henry E. Pelish | NUVL | Class A Common Stock | Options Exercise | 4.71% | 3,093 | 68,697 | 09 Apr 2026 | Direct | ||
| Henry E. Pelish | NUVL | Stock Option (Right to Buy) | Options Exercise | -27.1% | -3,093 | 8,309 | 09 Apr 2026 | Direct | ||
| James Richard Porter | NUVL | Class A Common Stock | Sale | -8.45% | $3,113,231 | $103.77 | -30,000 | 324,879 | 06 Apr 2026 | Direct |
| James Richard Porter | NUVL | Class A Common Stock | Options Exercise | 9.23% | 30,000 | 354,879 | 06 Apr 2026 | Direct | ||
| James Richard Porter | NUVL | Stock Option (Right to Buy) | Options Exercise | -18.6% | -30,000 | 131,494 | 06 Apr 2026 | Direct | ||
| Alexandra Balcom | NUVL | Class A Common Stock | Sale | -11.8% | $1,202,527 | $105.21 | -11,430 | 85,533 | 01 Apr 2026 | Direct |
| Alexandra Balcom | NUVL | Class A Common Stock | Options Exercise | 13.4% | 11,430 | 96,963 | 01 Apr 2026 | Direct | ||
| Alexandra Balcom | NUVL | Stock Option (Right to Buy) | Options Exercise | -7.61% | -11,430 | 138,796 | 01 Apr 2026 | Direct | ||
| Benjamin Lane | NUVL | Class A Common Stock | Award | 23.2% | 9,500 | 50,368 | 01 Apr 2026 | Direct | ||
| Benjamin Lane | NUVL | Stock Option (Right to Buy) | Award | 19,000 | 19,000 | 01 Apr 2026 | Direct | |||
| Darlene Noci | NUVL | Class A Common Stock | Sale | -8.65% | $537,943 | $97.81 | -5,500 | 58,117 | 30 Mar 2026 | Direct |
| Darlene Noci | NUVL | Class A Common Stock | Options Exercise | 9.46% | 5,500 | 63,617 | 30 Mar 2026 | Direct | ||
| Darlene Noci | NUVL | Stock Option (Right to Buy) | Options Exercise | -5.32% | -5,500 | 97,829 | 30 Mar 2026 | Direct | ||
| Deborah Ann Miller | NUVL | Class A Common Stock | Sale | -8.44% | $542,991 | $98.73 | -5,500 | 59,634 | 26 Mar 2026 | Direct |
| Deborah Ann Miller | NUVL | Class A Common Stock | Options Exercise | 9.22% | 5,500 | 65,134 | 26 Mar 2026 | Direct | ||
| Deborah Ann Miller | NUVL | Stock Option (Right to Buy) | Options Exercise | -6.17% | -5,500 | 83,608 | 26 Mar 2026 | Direct | ||
| Alexandra Balcom | NUVL | Class A Common Stock | Sale | -13.8% | $1,372,192 | $100.16 | -13,700 | 85,533 | 25 Mar 2026 | Direct |
| Alexandra Balcom | NUVL | Class A Common Stock | Sale | -10.3% | $1,094,418 | $95.75 | -11,430 | 99,233 | 24 Mar 2026 | Direct |
| Alexandra Balcom | NUVL | Class A Common Stock | Options Exercise | 11.5% | 11,430 | 110,663 | 24 Mar 2026 | Direct | ||
| Alexandra Balcom | NUVL | Stock Option (Right to Buy) | Options Exercise | -7.07% | -11,430 | 150,226 | 24 Mar 2026 | Direct | ||
| Henry E. Pelish | NUVL | Class A Common Stock | Sale | -7.22% | $505,171 | $98.98 | -5,104 | 65,604 | 13 Mar 2026 | Direct |
| Henry E. Pelish | NUVL | Class A Common Stock | Sale | -29.8% | $2,937,685 | $97.92 | -30,000 | 70,708 | 12 Mar 2026 | Direct |
| Henry E. Pelish | NUVL | Class A Common Stock | Options Exercise | 20.8% | 17,320 | 100,708 | 12 Mar 2026 | Direct | ||
| Henry E. Pelish | NUVL | Stock Option (Right to Buy) | Options Exercise | -89.1% | -17,320 | 2,113 | 12 Mar 2026 | Direct | ||
| James Richard Porter | NUVL | Class A Common Stock | Sale | -8.45% | $2,969,550 | $98.98 | -30,000 | 324,879 | 06 Mar 2026 | Direct |
| James Richard Porter | NUVL | Class A Common Stock | Options Exercise | 9.23% | 30,000 | 354,879 | 06 Mar 2026 | Direct | ||
| James Richard Porter | NUVL | Stock Option (Right to Buy) | Options Exercise | -16.9% | -30,000 | 147,780 | 06 Mar 2026 | Direct | ||
| Darlene Noci | NUVL | Class A Common Stock | Sale | -8.65% | $566,682 | $103.03 | -5,500 | 58,117 | 26 Feb 2026 | Direct |
| Darlene Noci | NUVL | Class A Common Stock | Options Exercise | 9.46% | 5,500 | 63,617 | 26 Feb 2026 | Direct | ||
| Darlene Noci | NUVL | Stock Option (Right to Buy) | Options Exercise | -5.05% | -5,500 | 103,329 | 26 Feb 2026 | Direct | ||
| Deborah Ann Miller | NUVL | Class A Common Stock | Sale | -8.44% | $566,788 | $103.05 | -5,500 | 59,634 | 26 Feb 2026 | Direct |
| Deborah Ann Miller | NUVL | Class A Common Stock | Options Exercise | 9.22% | 5,500 | 65,134 | 26 Feb 2026 | Direct | ||
| Deborah Ann Miller | NUVL | Stock Option (Right to Buy) | Options Exercise | -5.81% | -5,500 | 89,108 | 26 Feb 2026 | Direct | ||
| Darlene Noci | NUVL | Class A Common Stock | Sale | -8.65% | $561,422 | $102.08 | -5,500 | 58,117 | 29 Jan 2026 | Direct |
| Darlene Noci | NUVL | Class A Common Stock | Options Exercise | 9.46% | 5,500 | 63,617 | 29 Jan 2026 | Direct | ||
| Darlene Noci | NUVL | Stock Option (Right to Buy) | Options Exercise | -4.81% | -5,500 | 108,829 | 29 Jan 2026 | Direct | ||
| Deborah Ann Miller | NUVL | Class A Common Stock | Sale | -19.3% | $1,575,288 | $110.16 | -14,300 | 59,634 | 22 Jan 2026 | Direct |
| Deborah Ann Miller | NUVL | Class A Common Stock | Options Exercise | 24% | 14,300 | 73,934 | 22 Jan 2026 | Direct | ||
| Deborah Ann Miller | NUVL | Stock Option (Right to Buy) | Options Exercise | -16% | -14,300 | 75,154 | 22 Jan 2026 | Direct | ||
| Deborah Ann Miller | NUVL | Class A Common Stock | Sale | -1.16% | $76,888 | $109.84 | -700 | 59,634 | 21 Jan 2026 | Direct |
| Deborah Ann Miller | NUVL | Class A Common Stock | Options Exercise | 1.17% | 700 | 60,334 | 21 Jan 2026 | Direct | ||
| Deborah Ann Miller | NUVL | Stock Option (Right to Buy) | Options Exercise | -0.78% | -700 | 89,454 | 21 Jan 2026 | Direct | ||
| Henry E. Pelish | NUVL | Class A Common Stock | Award | 26.6% | 17,500 | 83,388 | 07 Jan 2026 | Direct | ||
| Henry E. Pelish | NUVL | Stock Option (Right to Buy) | Award | 17,500 | 17,500 | 07 Jan 2026 | Direct | |||
| Darlene Noci | NUVL | Class A Common Stock | Award | 43.1% | 17,500 | 58,117 | 07 Jan 2026 | Direct | ||
| Darlene Noci | NUVL | Stock Option (Right to Buy) | Award | 17,500 | 17,500 | 07 Jan 2026 | Direct | |||
| Deborah Ann Miller | NUVL | Class A Common Stock | Award | 41.5% | 17,500 | 59,634 | 07 Jan 2026 | Direct | ||
| Deborah Ann Miller | NUVL | Stock Option (Right to Buy) | Award | 17,500 | 17,500 | 07 Jan 2026 | Direct | |||
| Christopher Durant Turner | NUVL | Class A Common Stock | Award | 31.7% | 17,500 | 72,630 | 07 Jan 2026 | Direct |
* An asterisk sign (*) next to the price indicates that the price is likely invalid.