Quick Takeaways
- NUVL - Nuvalent, Inc. has 23 insiders with reported activity on this page.
- Net insider value flow over the last year: -$147,685,676.
- Recent transaction rows are available for direct filing-level review.
Insider Transactions Reported by 23 Insiders of Nuvalent, Inc.
- Symbol
- NUVL on Nasdaq
- Location
- Cambridge, MA
What Changed
- Buy value: ; sell value: $147,685,676.
- Net share flow: -1,566,786.
Why This Matters
- This page gives a plain-language issuer insider context before you inspect transaction-level evidence.
- Use the filing links below to verify timestamps, codes, and ownership impacts directly from SEC forms.
Source Evidence
Filed on Form 4
See Original Filing
Issuer insider activity is sourced from SEC Forms 3, 4, and 5.
Insider trading overview
Last 12 monthsNet insider flow leans to selling over the last 12 months. Net value: -$147,685,676.
Buys
$0
Shares: 0
Insiders: 0
Sells
$147,685,676
Shares: 1,566,786
Insiders: 8
Net
-$147,685,676
Shares: -1,566,786
Insiders: -8
| Window (months) | Buy shares | Sell shares | Buy $ | Sell $ | Net $ |
|---|---|---|---|---|---|
| 0-3 | 0 | 209,187 | $0 | $21,007,870 | -$21,007,870 |
| 3-6 | 0 | 857,454 | $0 | $82,540,128 | -$82,540,128 |
| 6-9 | 0 | 343,000 | $0 | $31,683,114 | -$31,683,114 |
| 9-12 | 0 | 157,145 | $0 | $12,454,565 | -$12,454,565 |
Nuvalent, Inc. executives and other stock owners filed with the SEC include:
| Name | Relationship | Holdings Value | Past Year Net Change | Change % | Valuation | Report Date |
|---|---|---|---|---|---|---|
| James E. Flynn | Director, Director by Deputization, 10%+ Owner | $1,639,268,060 | -$70,874,975 | -4.1% | Mixed | 24 Nov 2025 |
| Matthew Shair | Director | $174,338,383 | -$6,835,738 | -3.8% | Filing P/S | 24 Nov 2025 |
| Andrew A. F. Hack | Director | $127,579,408 | Mixed | 11 Dec 2024 | ||
| Wellington Biomedical Innovation Master Investors (Cayman) I L.P. | 10%+ Owner | $68,348,670 | Mixed | 02 Aug 2021 | ||
| DEERFIELD PARTNERS, L.P. | Director, Director by Deputization, 10%+ Owner | $49,491,000 | Mixed | 03 Nov 2022 | ||
| James Richard Porter | President and CEO, Director | $33,423,551 | -$22,718,667 | -40% | Filing P/S | 04 May 2026 |
| Alexandra Balcom | Chief Financial Officer | $8,550,734 | -$19,356,606 | -69% | Filing P/S | 01 May 2026 |
| Christopher Durant Turner | Chief Medical Officer | $7,305,924 | -$721,320 | -9% | Mixed | 05 Jan 2026 |
| Henry E. Pelish | Chief Scientific Officer | $6,888,420 | -$8,639,341 | -56% | Filing P/S | 09 Apr 2026 |
| Deborah Ann Miller | Chief Legal Officer | $5,937,757 | -$12,805,700 | -68% | Filing P/S | 30 Apr 2026 |
| Darlene Noci | Chief Development Officer | $5,879,696 | -$5,733,328 | -49% | Filing P/S | 29 Apr 2026 |
| Benjamin Lane | Chief Technical Operations Officer | $5,066,517 | Mixed | 01 Apr 2026 | ||
| Grant C. Bogle | Director | $437,121 | Mixed | 18 Jun 2025 | ||
| Joseph Pearlberg | Director | $384,714 | Mixed | 18 Jun 2025 | ||
| Sapna Srivastava | Director | $384,714 | Mixed | 18 Jun 2025 | ||
| Michael L. Meyers | Director | $384,714 | Mixed | 18 Jun 2025 | ||
| Anna Protopapas | Director | $384,714 | Mixed | 18 Jun 2025 | ||
| Cameron Wheeler | Director | $384,714 | Mixed | 18 Jun 2025 | ||
| Christy J. Oliger | Director | $296,871 | Mixed | 18 Jun 2025 | ||
| Ron Squarer | Director | $240,180 | Mixed | 10 Dec 2025 | ||
| Emily Conley | Director | $213,145 | Filing P/S | 23 Aug 2024 | ||
| Dwight Gary Gilliland | Director | $205,743 | Mixed | 12 Jun 2024 | ||
| Robert Bowers Jackson | Director | Mixed | 28 Jul 2021 |
Top shareholders of Nuvalent, Inc. (13F + 13D/G + 3/4/5)
Grouped by holder across the latest SEC ownership disclosures. Ownership % is shown only when it is directly reported or safely comparable across share classes.
Methodology: rows are grouped by holder and ranked by the holder's primary source value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
| Holder | Source | Role / Reporting | Ownership % | Shares | Holdings Value | 12M Net Δ | As of | Details |
|---|---|---|---|---|---|---|---|---|
| James E. Flynn |
13D/G
3/4/5
|
Deerfield Management Company, L.P. · Director, Director by Deputization, 10%+ Owner |
24%
|
22,852,280
|
$2,238,152,303 | -$71,496,004 | 31 Dec 2025 | |
| DEERFIELD MANAGEMENT COMPANY, L.P. |
13F
|
Company |
23%
|
17,248,450
|
$1,767,103,703 | — | 31 Mar 2026 | |
| FMR LLC |
13D/G
13F
|
Company |
13%
|
9,252,159
|
$959,541,420 | $0 | 31 Mar 2026 | |
| Paradigm Biocapital Advisors LP |
13F
|
Company |
7.3%
|
5,324,433
|
$545,488,161 | — | 31 Mar 2026 | |
| BlackRock, Inc. |
13F
13D/G
|
Company |
5%
from 13D/G
|
4,824,785
|
$494,299,250 | — | 31 Mar 2026 | |
| VANGUARD GROUP INC |
13D/G
|
The Vanguard Group |
6.8%
|
4,499,864
|
$330,650,007 | $0 | 31 Dec 2024 | |
| JPMORGAN CHASE & CO |
13F
|
Company |
4.2%
|
3,088,349
|
$298,705,153 | — | 31 Mar 2026 | |
| RA CAPITAL MANAGEMENT, L.P. |
13F
|
Company |
3.5%
|
2,534,145
|
$259,623,155 | — | 31 Mar 2026 | |
| VANGUARD PORTFOLIO MANAGEMENT LLC |
13F
|
Company |
3.4%
|
2,500,907
|
$256,217,922 | — | 31 Mar 2026 | |
| WELLINGTON MANAGEMENT GROUP LLP |
13F
|
Company |
3.4%
|
2,470,491
|
$253,101,802 | — | 31 Mar 2026 | |
| VANGUARD CAPITAL MANAGEMENT LLC |
13F
|
Company |
3.3%
|
2,428,488
|
$248,798,596 | — | 31 Mar 2026 | |
| PRICE T ROWE ASSOCIATES INC /MD/ |
13F
|
Company |
2.8%
|
2,056,133
|
$210,652,000 | — | 31 Mar 2026 | |
| STATE STREET CORP |
13F
|
Company |
2.8%
|
2,035,831
|
$208,570,886 | — | 31 Mar 2026 | |
| Polar Capital Holdings Plc |
13F
|
Company |
2.5%
|
1,831,253
|
$187,611,870 | — | 31 Mar 2026 | |
| Matthew Shair |
3/4/5
|
Director |
—
mixed-class rows
|
1,583,013
mixed-class rows
|
$174,338,383 | -$6,835,738 | 24 Nov 2025 | |
| PERCEPTIVE ADVISORS LLC |
13F
|
Company |
2.2%
|
1,580,505
|
$161,922,737 | — | 31 Mar 2026 | |
| T. Rowe Price Investment Management, Inc. |
13F
|
Company |
1.9%
|
1,413,637
|
$144,828,000 | — | 31 Mar 2026 | |
| Deep Track Capital, LP |
13F
|
Company |
1.9%
|
1,376,324
|
$141,004,394 | — | 31 Mar 2026 | |
| GEODE CAPITAL MANAGEMENT, LLC |
13F
|
Company |
1.8%
|
1,298,107
|
$133,017,356 | — | 31 Mar 2026 | |
| Andrew A. F. Hack |
3/4/5
|
Director |
—
mixed-class rows
|
1,453,555
mixed-class rows
|
$127,579,408 | — | 11 Dec 2024 | |
| JANUS HENDERSON GROUP PLC |
13F
|
Company |
1.7%
|
1,237,779
|
$126,837,899 | — | 31 Mar 2026 | |
| Bellevue Group AG |
13F
|
Company |
1.4%
|
1,053,268
|
$107,907,307 | — | 31 Mar 2026 | |
| Commodore Capital LP |
13F
|
Company |
1.1%
|
833,600
|
$85,402,320 | — | 31 Mar 2026 | |
| ALLIANCEBERNSTEIN L.P. |
13F
|
Company |
1.1%
|
784,023
|
$78,864,874 | — | 31 Mar 2026 | |
| ADAGE CAPITAL PARTNERS GP, L.L.C. |
13F
|
Company |
1%
|
748,896
|
$76,724,395 | — | 31 Mar 2026 | |
| BRAIDWELL LP |
13F
|
Company |
0.95%
|
700,429
|
$71,758,951 | — | 31 Mar 2026 | |
| Wellington Biomedical Innovation Master Investors (Cayman) I L.P. |
3/4/5
|
10%+ Owner |
—
class O/S missing
|
897,671
|
$68,348,670 | — | 02 Aug 2021 | |
| Woodline Partners LP |
13F
|
Company |
0.83%
|
610,459
|
$62,541,525 | — | 31 Mar 2026 | |
| AMERIPRISE FINANCIAL INC |
13F
|
Company |
0.77%
|
563,768
|
$57,758,261 | — | 31 Mar 2026 | |
| GOLDMAN SACHS GROUP INC |
13F
|
Company |
0.73%
|
537,158
|
$55,031,837 | — | 31 Mar 2026 | |
| DEERFIELD PARTNERS, L.P. |
3/4/5
|
Director, Director by Deputization, 10%+ Owner |
—
class O/S missing
|
650,000
|
$49,491,000 | — | 03 Nov 2022 | |
| Vestal Point Capital, LP |
13F
|
Company |
0.66%
|
481,715
|
$49,351,702 | — | 31 Mar 2026 | |
| DRIEHAUS CAPITAL MANAGEMENT LLC |
13F
|
Company |
0.66%
|
481,180
|
$49,296,891 | — | 31 Mar 2026 | |
| Hood River Capital Management LLC |
13F
|
Company |
0.65%
|
479,998
|
$49,175,795 | — | 31 Mar 2026 | |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13F
|
Company |
0.61%
|
450,801
|
$46,184,562 | — | 31 Mar 2026 | |
| FRANKLIN RESOURCES INC |
13F
|
Company |
0.59%
|
434,742
|
$44,539,319 | — | 31 Mar 2026 | |
| AMERICAN CENTURY COMPANIES INC |
13F
|
Company |
0.59%
|
431,067
|
$44,162,951 | — | 31 Mar 2026 | |
| NORTHERN TRUST CORP |
13F
|
Company |
0.58%
|
429,373
|
$43,989,264 | — | 31 Mar 2026 | |
| Pictet Asset Management Holding SA |
13F
|
Company |
0.56%
|
410,485
|
$42,054,188 | — | 31 Mar 2026 | |
| Invesco Ltd. |
13F
|
Company |
0.56%
|
408,285
|
$41,828,798 | — | 31 Mar 2026 | |
| FRONTIER CAPITAL MANAGEMENT CO LLC |
13F
|
Company |
0.54%
|
395,546
|
$40,523,686 | — | 31 Mar 2026 | |
| S.c.a. Candriam |
13F
|
Individual |
0.53%
|
391,306
|
$40,089,300 | — | 31 Mar 2026 | |
| First Turn Management, LLC |
13F
|
Company |
0.5%
|
370,344
|
$37,941,743 | — | 31 Mar 2026 | |
| VANGUARD FIDUCIARY TRUST CO |
13F
|
Company |
0.5%
|
364,167
|
$37,308,909 | — | 31 Mar 2026 | |
| UBS Group AG |
13F
|
Company |
0.49%
|
363,098
|
$37,199,391 | — | 31 Mar 2026 | |
| SILVERARC CAPITAL MANAGEMENT, LLC |
13F
|
Company |
0.48%
|
354,914
|
$36,360,939 | — | 31 Mar 2026 | |
| James Richard Porter |
3/4/5
|
President and CEO, Director |
—
mixed-class rows
|
503,565
mixed-class rows
|
$33,423,551 | -$22,718,667 | 04 May 2026 | |
| Tri Locum Partners LP |
13F
|
Company |
0.42%
|
308,506
|
$31,606,440 | — | 31 Mar 2026 | |
| Jones Hill Capital LP |
13F
|
Company |
0.41%
|
300,830
|
$30,820,034 | — | 31 Mar 2026 | |
| Affinity Asset Advisors, LLC |
13F
|
Company |
0.41%
|
300,000
|
$30,735,000 | — | 31 Mar 2026 |
Recent Insider Transactions by Companies or Individuals for Nuvalent, Inc.
Showing up to 300 most recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | Value $ | * Price $ | Shares | Shares Owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| James Richard Porter | NUVL | Class A Common Stock | Sale | -8.45% | $3,050,712 | $101.69 | -30,000 | 324,879 | 04 May 2026 | Direct |
| James Richard Porter | NUVL | Class A Common Stock | Options Exercise | 9.23% | 30,000 | 354,879 | 04 May 2026 | Direct | ||
| James Richard Porter | NUVL | Stock Option (Right to Buy) | Options Exercise | -14.4% | -30,000 | 178,686 | 04 May 2026 | Direct | ||
| Alexandra Balcom | NUVL | Class A Common Stock | Sale | -11.8% | $1,131,600 | $99.00 | -11,430 | 85,533 | 01 May 2026 | Direct |
| Alexandra Balcom | NUVL | Class A Common Stock | Options Exercise | 13.4% | 11,430 | 96,963 | 01 May 2026 | Direct | ||
| Alexandra Balcom | NUVL | Stock Option (Right to Buy) | Options Exercise | -31.5% | -11,430 | 24,830 | 01 May 2026 | Direct | ||
| Deborah Ann Miller | NUVL | Class A Common Stock | Sale | -8.44% | $545,691 | $99.22 | -5,500 | 59,634 | 30 Apr 2026 | Direct |
| Deborah Ann Miller | NUVL | Class A Common Stock | Options Exercise | 9.22% | 5,500 | 65,134 | 30 Apr 2026 | Direct | ||
| Deborah Ann Miller | NUVL | Stock Option (Right to Buy) | Options Exercise | -6.58% | -5,500 | 78,108 | 30 Apr 2026 | Direct | ||
| Darlene Noci | NUVL | Class A Common Stock | Sale | -8.65% | $547,524 | $99.55 | -5,500 | 58,117 | 29 Apr 2026 | Direct |
| Darlene Noci | NUVL | Class A Common Stock | Options Exercise | 9.46% | 5,500 | 63,617 | 29 Apr 2026 | Direct | ||
| Darlene Noci | NUVL | Stock Option (Right to Buy) | Options Exercise | -5.62% | -5,500 | 92,329 | 29 Apr 2026 | Direct | ||
| Henry E. Pelish | NUVL | Class A Common Stock | Sale | -4.5% | $323,164 | $104.48 | -3,093 | 65,604 | 09 Apr 2026 | Direct |
| Henry E. Pelish | NUVL | Class A Common Stock | Options Exercise | 4.71% | 3,093 | 68,697 | 09 Apr 2026 | Direct | ||
| Henry E. Pelish | NUVL | Stock Option (Right to Buy) | Options Exercise | -27.1% | -3,093 | 8,309 | 09 Apr 2026 | Direct | ||
| James Richard Porter | NUVL | Class A Common Stock | Sale | -8.45% | $3,113,231 | $103.77 | -30,000 | 324,879 | 06 Apr 2026 | Direct |
| James Richard Porter | NUVL | Class A Common Stock | Options Exercise | 9.23% | 30,000 | 354,879 | 06 Apr 2026 | Direct | ||
| James Richard Porter | NUVL | Stock Option (Right to Buy) | Options Exercise | -18.6% | -30,000 | 131,494 | 06 Apr 2026 | Direct | ||
| Alexandra Balcom | NUVL | Class A Common Stock | Sale | -11.8% | $1,202,527 | $105.21 | -11,430 | 85,533 | 01 Apr 2026 | Direct |
| Alexandra Balcom | NUVL | Class A Common Stock | Options Exercise | 13.4% | 11,430 | 96,963 | 01 Apr 2026 | Direct | ||
| Alexandra Balcom | NUVL | Stock Option (Right to Buy) | Options Exercise | -7.61% | -11,430 | 138,796 | 01 Apr 2026 | Direct | ||
| Benjamin Lane | NUVL | Class A Common Stock | Award | 23.2% | 9,500 | 50,368 | 01 Apr 2026 | Direct | ||
| Benjamin Lane | NUVL | Stock Option (Right to Buy) | Award | 19,000 | 19,000 | 01 Apr 2026 | Direct | |||
| Darlene Noci | NUVL | Class A Common Stock | Sale | -8.65% | $537,943 | $97.81 | -5,500 | 58,117 | 30 Mar 2026 | Direct |
| Darlene Noci | NUVL | Class A Common Stock | Options Exercise | 9.46% | 5,500 | 63,617 | 30 Mar 2026 | Direct | ||
| Darlene Noci | NUVL | Stock Option (Right to Buy) | Options Exercise | -5.32% | -5,500 | 97,829 | 30 Mar 2026 | Direct | ||
| Deborah Ann Miller | NUVL | Class A Common Stock | Sale | -8.44% | $542,991 | $98.73 | -5,500 | 59,634 | 26 Mar 2026 | Direct |
| Deborah Ann Miller | NUVL | Class A Common Stock | Options Exercise | 9.22% | 5,500 | 65,134 | 26 Mar 2026 | Direct | ||
| Deborah Ann Miller | NUVL | Stock Option (Right to Buy) | Options Exercise | -6.17% | -5,500 | 83,608 | 26 Mar 2026 | Direct | ||
| Alexandra Balcom | NUVL | Class A Common Stock | Sale | -13.8% | $1,372,192 | $100.16 | -13,700 | 85,533 | 25 Mar 2026 | Direct |
| Alexandra Balcom | NUVL | Class A Common Stock | Sale | -10.3% | $1,094,418 | $95.75 | -11,430 | 99,233 | 24 Mar 2026 | Direct |
| Alexandra Balcom | NUVL | Class A Common Stock | Options Exercise | 11.5% | 11,430 | 110,663 | 24 Mar 2026 | Direct | ||
| Alexandra Balcom | NUVL | Stock Option (Right to Buy) | Options Exercise | -7.07% | -11,430 | 150,226 | 24 Mar 2026 | Direct | ||
| Henry E. Pelish | NUVL | Class A Common Stock | Sale | -7.22% | $505,171 | $98.98 | -5,104 | 65,604 | 13 Mar 2026 | Direct |
| Henry E. Pelish | NUVL | Class A Common Stock | Sale | -29.8% | $2,937,685 | $97.92 | -30,000 | 70,708 | 12 Mar 2026 | Direct |
| Henry E. Pelish | NUVL | Class A Common Stock | Options Exercise | 20.8% | 17,320 | 100,708 | 12 Mar 2026 | Direct | ||
| Henry E. Pelish | NUVL | Stock Option (Right to Buy) | Options Exercise | -89.1% | -17,320 | 2,113 | 12 Mar 2026 | Direct | ||
| James Richard Porter | NUVL | Class A Common Stock | Sale | -8.45% | $2,969,550 | $98.98 | -30,000 | 324,879 | 06 Mar 2026 | Direct |
| James Richard Porter | NUVL | Class A Common Stock | Options Exercise | 9.23% | 30,000 | 354,879 | 06 Mar 2026 | Direct | ||
| James Richard Porter | NUVL | Stock Option (Right to Buy) | Options Exercise | -16.9% | -30,000 | 147,780 | 06 Mar 2026 | Direct | ||
| Darlene Noci | NUVL | Class A Common Stock | Sale | -8.65% | $566,682 | $103.03 | -5,500 | 58,117 | 26 Feb 2026 | Direct |
| Darlene Noci | NUVL | Class A Common Stock | Options Exercise | 9.46% | 5,500 | 63,617 | 26 Feb 2026 | Direct | ||
| Darlene Noci | NUVL | Stock Option (Right to Buy) | Options Exercise | -5.05% | -5,500 | 103,329 | 26 Feb 2026 | Direct | ||
| Deborah Ann Miller | NUVL | Class A Common Stock | Sale | -8.44% | $566,788 | $103.05 | -5,500 | 59,634 | 26 Feb 2026 | Direct |
| Deborah Ann Miller | NUVL | Class A Common Stock | Options Exercise | 9.22% | 5,500 | 65,134 | 26 Feb 2026 | Direct | ||
| Deborah Ann Miller | NUVL | Stock Option (Right to Buy) | Options Exercise | -5.81% | -5,500 | 89,108 | 26 Feb 2026 | Direct | ||
| Darlene Noci | NUVL | Class A Common Stock | Sale | -8.65% | $561,422 | $102.08 | -5,500 | 58,117 | 29 Jan 2026 | Direct |
| Darlene Noci | NUVL | Class A Common Stock | Options Exercise | 9.46% | 5,500 | 63,617 | 29 Jan 2026 | Direct | ||
| Darlene Noci | NUVL | Stock Option (Right to Buy) | Options Exercise | -4.81% | -5,500 | 108,829 | 29 Jan 2026 | Direct | ||
| Deborah Ann Miller | NUVL | Class A Common Stock | Sale | -19.3% | $1,575,288 | $110.16 | -14,300 | 59,634 | 22 Jan 2026 | Direct |
* An asterisk sign (*) next to the price indicates that the price is likely invalid.