SEC ownership of Nuvalent, Inc.

Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001861560.

Comparable stake leader

VANGUARD GROUP INC

Disclosed value leader

DEERFIELD MANAGEMENT COMPANY, L.P.

Comparable rows

3/50

Latest evidence

15 Jul 2026

Top shareholders Insider holders Latest transactions
Parsed ownership sources
13D/G, 13F, and 3/4/5
Source: Parsed SEC ownership filingsUse: Compare filing families carefully
Largest SEC-reported holder
VANGUARD GROUP INC
Ranking: Comparable ownership first, then disclosed value
Ownership snapshot CIK-linked ownership evidence from parsed SEC filings. 3 signals
Comparable ownership rows
3 of 50
Meaning: Rows with safely comparable ownership %
Latest 13D/G holder
VANGUARD GROUP INC
Source: Latest parsed Schedule 13D/G stake
Latest parsed ownership date
15 Jul 2026
Freshness: Most recent filing date in this holder set
Issuer Names, identifiers, and filing context for this profile. 2 identity fields
Issuer CIK
0001861560
Issuer location
Cambridge, MA

Ownership snapshot

Top shareholders of Nuvalent, Inc. (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
VANGUARD GROUP INC
Disclosed value leader
DEERFIELD MANAGEMENT COMP...
Comparable rows
3/50
Latest evidence
15 Jul 2026
13D/G 13F 3/4/5 Lead comparable stake: 6.8% 47 rows are not safely comparable across share classes. 13D/G row: VANGUARD GROUP INC Showing 1-8 of 50 holder rows.

Quick read

VANGUARD GROUP INC leads the comparable SEC ownership view at 6.8%.

3 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens VANGUARD GROUP INC's linked filing trail.
Comparable ownership Top 3
VANGUARD GROUP INC 6.8%
BlackRock, Inc. 5%
FMR LLC 1.9%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-8 of 50 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
VANGUARD GROUP INC
13D/G
The Vanguard Group
13D/G
6.8%
Reported 13D/G · 31 Dec 2024
$330,650,007
4,499,864 shares
 $0 31 Dec 2024
BlackRock, Inc.
13F 13D/G
Company
13F 13D/G
5%
Reported 13D/G · 30 Jun 2025
$689,823,951
5,585,619 shares
 — 30 Jun 2026
FMR LLC
13F 13D/G
Company
13F 13D/G
1.9%
Reported 13D/G · 30 Jun 2026
$175,072,424
1,417,590 shares
 — 30 Jun 2026
DEERFIELD MANAGEMENT COMPANY, L.P.
13F 3/4/5
Company · Director, Director by Deputization, 10%+ Owner
13F 3/4/5
—
denominator unverified
$2,130,183,575
17,248,450 shares
 — 30 Jun 2026
Wellington Biomedical Innovation Master Investors (Cayman) I L.P.
3/4/5
10%+ Owner
3/4/5
—
denominator unverified
$68,348,670
897,671 shares
 — 02 Aug 2021
James E. Flynn
3/4/5
Director, Director by Deputization, 10%+ Owner
3/4/5
—
mixed-class rows
$66,945,337
657,591 shares
mixed-class rows
 -$70,874,975 15 Jul 2026
DEERFIELD PARTNERS, L.P.
3/4/5
Director, Director by Deputization, 10%+ Owner
3/4/5
—
denominator unverified
$49,491,000
650,000 shares
 — 15 Jul 2026
Paradigm Biocapital Advisors LP
13F
Company
13F
—
denominator unverified
$731,667,476
5,924,433 shares
 — 30 Jun 2026
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Forms 3/4/5 flow

Insider trading overview

Net insider flow leans to selling over the last 12 months. Net value: -$127,753,397.

Buys
$0
Insiders: 0
Sells
$127,753,397
Insiders: 8
Net
-$127,753,397
Shares: -1,287,341
Window
Last 12 months
4 rolling buckets
Buy value Sell value
Shares: 0 Shares: 1,287,341
Window (months) Buy shares Sell shares Buy value Sell value Net value
0-3 0 0 $0 $0 $0
3-6 0 196,901 $0 $21,654,769 -$21,654,769
6-9 0 162,257 $0 $16,279,867 -$16,279,867
9-12 0 928,183 $0 $89,818,761 -$89,818,761

Reporting owners

Insider holders from Forms 3/4/5

Showing 1-20 of 29 reporting-owner rows connected to Nuvalent, Inc.. Open a relationship link for the CIK-to-CIK filing trail.

Rows
29
Largest Forms 3/4/5 holder
Matthew Shair
Net 12M change
-$127.75MFull value: -$127,753,397 · USD · 12-month change
Latest report
15 Jul 2026
Name Relationship Holdings Value Past Year Net Change Change % Valuation Report Date
Matthew Shair Director $174,338,383 -$820,274 -0.47% Filing P/S 24 Nov 2025
Andrew A. F. Hack Director $127,579,408 Mixed 11 Dec 2024
Wellington Biomedical Innovation Master Investors (Cayman) I L.P. 10%+ Owner $68,348,670 Mixed 02 Aug 2021
James E. Flynn Director, Director by Deputization, 10%+ Owner $66,945,337 -$70,874,975 -51% Mixed 15 Jul 2026
DEERFIELD MANAGEMENT COMPANY, L.P. Director, Director by Deputization, 10%+ Owner $66,945,337 Mixed 15 Jul 2026
DEERFIELD PARTNERS, L.P. Director, Director by Deputization, 10%+ Owner $49,491,000 Mixed 15 Jul 2026
Ron Squarer Director $643,488 Mixed 15 Jul 2026
Joseph Pearlberg Director $384,714 Mixed 18 Jun 2025
Emily Conley Director $213,145 Filing P/S 23 Aug 2024
Dwight Gary Gilliland Director $205,743 Mixed 12 Jun 2024
Deborah Ann Miller Chief Legal Officer $0 -$10,977,061 -100% Mixed 15 Jul 2026
Benjamin Lane Chief Technical Operations Officer $0 Mixed 15 Jul 2026
Deerfield Healthcare Innovations Fund, L.P. Director, Director by Deputization, 10%+ Owner $0 Mixed 15 Jul 2026
James Richard Porter President and CEO, Director $0 -$18,169,358 -100% Mixed 15 Jul 2026
Sapna Srivastava Director $0 Mixed 15 Jul 2026
Christy J. Oliger Director $0 Mixed 15 Jul 2026
Alexandra Balcom Chief Financial Officer $0 -$10,909,225 -100% Mixed 15 Jul 2026
Henry E. Pelish Chief Scientific Officer $0 -$4,529,136 -100% Mixed 15 Jul 2026
Grant C. Bogle Director $0 Mixed 15 Jul 2026
Anna Protopapas Director $0 Mixed 15 Jul 2026

Recent insider transactions for Nuvalent, Inc.

Showing up to 300 recent insider transactions from the last 12 months.

Insider Symbol Class Transaction % SEC-reported value SEC-reported price Shares Shares owned Date Ownership
Flynn James E NUVL Class A Common Stock - Restricted Stock Units Disposed to Issuer -100% -3,444 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
James E. Flynn NUVL Class A Common Stock - Restricted Stock Units Disposed to Issuer -100% -3,444 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
James E. Flynn NUVL Class A Common Stock - Restricted Stock Units Disposed to Issuer -100% -3,444 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
Flynn James E NUVL Class A Common Stock - Restricted Stock Units Disposed to Issuer -100% -3,444 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
Flynn James E NUVL Class A Common Stock - Restricted Stock Units Disposed to Issuer -100% -3,444 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
James E. Flynn NUVL Class A Common Stock - Restricted Stock Units Disposed to Issuer -100% -3,444 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
Flynn James E NUVL Class A Common Stock - Restricted Stock Units Disposed to Issuer -100% -3,444 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
James E. Flynn NUVL Class A Common Stock - Restricted Stock Units Disposed to Issuer -100% -3,444 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
Flynn James E NUVL Class A Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -10,292 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
James E. Flynn NUVL Class A Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -10,292 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
James E. Flynn NUVL Class A Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -10,292 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
Flynn James E NUVL Class A Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -10,292 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
Flynn James E NUVL Class A Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -10,292 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
James E. Flynn NUVL Class A Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -10,292 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
Flynn James E NUVL Class A Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -10,292 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
James E. Flynn NUVL Class A Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -10,292 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
Flynn James E NUVL Class A Common Stock Disposed to Issuer -100% -650,000 0 15 Jul 2026 Through Deerfield Partners, L.P.
James E. Flynn NUVL Class A Common Stock Disposed to Issuer -100% -650,000 0 15 Jul 2026 Through Deerfield Partners, L.P.
James E. Flynn NUVL Class A Common Stock Disposed to Issuer -100% -650,000 0 15 Jul 2026 Through Deerfield Partners, L.P.
Flynn James E NUVL Class A Common Stock Disposed to Issuer -100% -650,000 0 15 Jul 2026 Through Deerfield Partners, L.P.
Flynn James E NUVL Class A Common Stock Disposed to Issuer -100% -650,000 0 15 Jul 2026 Through Deerfield Partners, L.P.
James E. Flynn NUVL Class A Common Stock Disposed to Issuer -100% -650,000 0 15 Jul 2026 Through Deerfield Partners, L.P.
Flynn James E NUVL Class A Common Stock Disposed to Issuer -100% -650,000 0 15 Jul 2026 Through Deerfield Partners, L.P.
James E. Flynn NUVL Class A Common Stock Disposed to Issuer -100% -650,000 0 15 Jul 2026 Through Deerfield Partners, L.P.
Flynn James E NUVL Class A Common Stock Disposed to Issuer -100% -8,299,225 0 15 Jul 2026 Through Deerfield Healthcare Innovations Fund, L.P.
James E. Flynn NUVL Class A Common Stock Disposed to Issuer -100% -8,299,225 0 15 Jul 2026 Through Deerfield Healthcare Innovations Fund, L.P.
James E. Flynn NUVL Class A Common Stock Disposed to Issuer -100% -8,299,225 0 15 Jul 2026 Through Deerfield Healthcare Innovations Fund, L.P.
Flynn James E NUVL Class A Common Stock Disposed to Issuer -100% -8,299,225 0 15 Jul 2026 Through Deerfield Healthcare Innovations Fund, L.P.
Flynn James E NUVL Class A Common Stock Disposed to Issuer -100% -8,299,225 0 15 Jul 2026 Through Deerfield Healthcare Innovations Fund, L.P.
James E. Flynn NUVL Class A Common Stock Disposed to Issuer -100% -8,299,225 0 15 Jul 2026 Through Deerfield Healthcare Innovations Fund, L.P.
Flynn James E NUVL Class A Common Stock Disposed to Issuer -100% -8,299,225 0 15 Jul 2026 Through Deerfield Healthcare Innovations Fund, L.P.
James E. Flynn NUVL Class A Common Stock Disposed to Issuer -100% -8,299,225 0 15 Jul 2026 Through Deerfield Healthcare Innovations Fund, L.P.
Flynn James E NUVL Class A Common Stock Disposed to Issuer -100% -8,299,225 0 15 Jul 2026 Through Deerfield Private Design Fund IV, L.P.
James E. Flynn NUVL Class A Common Stock Disposed to Issuer -100% -8,299,225 0 15 Jul 2026 Through Deerfield Private Design Fund IV, L.P.
James E. Flynn NUVL Class A Common Stock Disposed to Issuer -100% -8,299,225 0 15 Jul 2026 Through Deerfield Private Design Fund IV, L.P.
Flynn James E NUVL Class A Common Stock Disposed to Issuer -100% -8,299,225 0 15 Jul 2026 Through Deerfield Private Design Fund IV, L.P.
Flynn James E NUVL Class A Common Stock Disposed to Issuer -100% -8,299,225 0 15 Jul 2026 Through Deerfield Private Design Fund IV, L.P.
James E. Flynn NUVL Class A Common Stock Disposed to Issuer -100% -8,299,225 0 15 Jul 2026 Through Deerfield Private Design Fund IV, L.P.
Flynn James E NUVL Class A Common Stock Disposed to Issuer -100% -8,299,225 0 15 Jul 2026 Through Deerfield Private Design Fund IV, L.P.
James E. Flynn NUVL Class A Common Stock Disposed to Issuer -100% -8,299,225 0 15 Jul 2026 Through Deerfield Private Design Fund IV, L.P.
Flynn James E NUVL Stock Option (right to buy) Disposed to Issuer -100% -171,872 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
James E. Flynn NUVL Stock Option (right to buy) Disposed to Issuer -100% -171,872 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
James E. Flynn NUVL Stock Option (right to buy) Disposed to Issuer -100% -171,872 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
Flynn James E NUVL Stock Option (right to buy) Disposed to Issuer -100% -171,872 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
Flynn James E NUVL Stock Option (right to buy) Disposed to Issuer -100% -171,872 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
James E. Flynn NUVL Stock Option (right to buy) Disposed to Issuer -100% -171,872 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
Flynn James E NUVL Stock Option (right to buy) Disposed to Issuer -100% -171,872 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
James E. Flynn NUVL Stock Option (right to buy) Disposed to Issuer -100% -171,872 0 15 Jul 2026 Through Deerfield Mangement Company, L.P.
Flynn James E NUVL Class B Common Stock Disposed to Issuer -100% -2,717,627 0 15 Jul 2026 Through Deerfield Healthcare Innovations Fund, L.P.
James E. Flynn NUVL Class B Common Stock Disposed to Issuer -100% -2,717,627 0 15 Jul 2026 Through Deerfield Healthcare Innovations Fund, L.P.
* marks a reported price that did not pass the local price check.
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