SEC ownership of Mersana Therapeutics, Inc.

Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001442836.

Comparable stake leader

VANGUARD GROUP INC

Disclosed value leader

Crossover I. Scsp Nextech

Comparable rows

3/14

Latest evidence

06 Jan 2026

Ownership snapshot CIK-linked ownership evidence from parsed SEC filings. 3 signals
Comparable ownership rows
3 of 14
Meaning: Rows with safely comparable ownership %
Latest 13D/G holder
VANGUARD GROUP INC
Source: Latest parsed Schedule 13D/G stake
Latest parsed ownership date
06 Jan 2026
Freshness: Most recent filing date in this holder set
Issuer Names, identifiers, and filing context for this profile. 2 identity fields
Issuer CIK
0001442836
Issuer location
Cambridge, MA

Ownership snapshot

Top shareholders of Mersana Therapeutics, Inc. (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
VANGUARD GROUP INC
Disclosed value leader
Crossover I. Scsp Nextech
Comparable rows
3/14
Latest evidence
06 Jan 2026
13D/G 3/4/5 Lead comparable stake: 4.2% 11 rows are not safely comparable across share classes. 13D/G row: VANGUARD GROUP INC Showing 1-8 of 14 holder rows.

Quick read

VANGUARD GROUP INC leads the comparable SEC ownership view at 4.2%.

3 of 14 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens VANGUARD GROUP INC's linked filing trail.
Comparable ownership Top 3
VANGUARD GROUP INC 4.2%
BlackRock, Inc. 3%
Venrock Healthcare Capital Partne... 2.9%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-8 of 14 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
VANGUARD GROUP INC
13D/G
The Vanguard Group
4.2%
$6,082,136
210,301 shares
$0 31 Dec 2025
BlackRock, Inc.
13D/G
3%
$1,103,358
3,761,876 shares
-$1,338,033 30 Jun 2025
Venrock Healthcare Capital Partners III, L.P.
13D/G
2.9%
$1,286,757
3,574,325 shares
-$2,406,047 31 Mar 2025
Crossover I. Scsp Nextech
3/4/5
10%+ Owner
class O/S missing
$22,927,767
12,067,246 shares
20 Dec 2024
EcoR1 Capital, LLC
3/4/5
10%+ Owner
mixed-class rows
$21,523,200
19,364,688 shares
mixed-class rows
19 Dec 2024
Brian DeSchuytner
3/4/5
SVP, COO & CFO
mixed-class rows
$194,332
62,500 shares
mixed-class rows
06 Jan 2026
Alejandra Carvajal
3/4/5
SVP, Chief Legal Officer
mixed-class rows
$166,917
54,167 shares
mixed-class rows
06 Jan 2026
Timothy B. Lowinger
3/4/5
SVP, Chief Sci.&Tech. Officer
mixed-class rows
$166,917
54,167 shares
mixed-class rows
06 Jan 2026
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Forms 3/4/5 flow

Insider trading overview

Net insider flow leans to selling over the last 12 months. Net value: -$762.

Buys
$0
Insiders: 0
Sells
$762
Insiders: 1
Net
-$762
Shares: -77
Window
Last 12 months
4 rolling buckets
Buy value Sell value
Shares: 0 Shares: 77
Window (months) Buy shares Sell shares Buy value Sell value Net value
0-3 0 0 $0 $0 $0
3-6 0 0 $0 $0 $0
6-9 0 0 $0 $0 $0
9-12 0 77 $0 $762 -$762

Reporting owners

Insider holders from Forms 3/4/5

Showing 1-18 of 18 reporting-owner rows connected to Mersana Therapeutics, Inc.. Open a relationship link for the CIK-to-CIK filing trail.

Rows
18
Largest Forms 3/4/5 holder
Crossover I. Scsp Nextech
Net 12M change
-$762
Latest report
06 Jan 2026
Name Relationship Holdings Value Past Year Net Change Change % Valuation Report Date
Crossover I. Scsp Nextech 10%+ Owner $22,927,767 Mixed 20 Dec 2024
EcoR1 Capital, LLC 10%+ Owner $21,523,200 Mixed 19 Dec 2024
Brian DeSchuytner Svp, Coo & Cfo $194,332 Mixed 06 Jan 2026
Timothy B. Lowinger SVP, Chief Sci.&Tech. Officer $166,917 Mixed 06 Jan 2026
Alejandra Carvajal SVP, Chief Legal Officer $166,917 Mixed 06 Jan 2026
Tushar Misra SVP, Chief Manuf. Officer $161,606 Mixed 13 Jan 2024
Arvin Yang SVP, Chief Medical Officer $141,110 Mixed 13 Jan 2023
Martin H. Huber Jr. President, CEO, Director $105,212 Mixed 06 Jan 2026
Michael J. Kaufman Chief Manufacturing Officer $88,406 Mixed 15 Jul 2021
Ashish Mandelia VP, Chief Accounting Officer $54,835 Mixed 06 Jan 2026
Mohan Bala SVP, Chief Development $39,375 -$762 -1.9% Mixed 06 Jan 2026
Allene M. Diaz Director $0 Mixed 06 Jan 2026
Kristen Hege Director $0 Mixed 06 Jan 2026
Anna Protopapas Director $0 Mixed 06 Jan 2026
David M. Mott Director $0 Mixed 06 Jan 2026
Lawrence M. Alleva Director $0 Mixed 06 Jan 2026
Willard H. Dere Director $0 Mixed 06 Jan 2026
Andrew A. F. Hack Director $0 Mixed 06 Jan 2026

Recent insider transactions for Mersana Therapeutics, Inc.

Showing up to 300 recent insider transactions from the last 12 months.

Insider Symbol Class Transaction % SEC-reported value SEC-reported price Shares Shares owned Date Ownership
Andrew A. F. Hack MRSN Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -346,545 0 06 Jan 2026 See Footnote
Andrew A. F. Hack MRSN Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -578 0 06 Jan 2026 Direct
Andrew A. F. Hack MRSN Stock Option (right to buy) Disposed to Issuer -100% -12,609 0 06 Jan 2026 Direct
Kristen Hege MRSN Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -578 0 06 Jan 2026 Direct
Kristen Hege MRSN Stock Option (right to buy) Disposed to Issuer -100% -14,082 0 06 Jan 2026 Direct
Allene M. Diaz MRSN Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -578 0 06 Jan 2026 Direct
Allene M. Diaz MRSN Stock Option (right to buy) Disposed to Issuer -100% -9,181 0 06 Jan 2026 Direct
Willard H. Dere MRSN Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -1,567 0 06 Jan 2026 Direct
Willard H. Dere MRSN Stock Option (right to buy) Disposed to Issuer -100% -11,996 0 06 Jan 2026 Direct
Alejandra Carvajal MRSN Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -3,131 0 06 Jan 2026 Direct
Alejandra Carvajal MRSN Restricted Stock Units Disposed to Issuer -100% -4,483 0 06 Jan 2026 Direct
Alejandra Carvajal MRSN Stock Option (right to buy) Disposed to Issuer -100% -31,497 0 06 Jan 2026 Direct
Mohan Bala MRSN Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -2,927 0 06 Jan 2026 Direct
Mohan Bala MRSN Restricted Stock Units Disposed to Issuer -100% -4,950 0 06 Jan 2026 Direct
Mohan Bala MRSN Stock Option (right to buy) Disposed to Issuer -100% -32,546 0 06 Jan 2026 Direct
Lawrence M. Alleva MRSN Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -84 0 06 Jan 2026 See Footnote
Lawrence M. Alleva MRSN Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -578 0 06 Jan 2026 Direct
Lawrence M. Alleva MRSN Stock Option (right to buy) Disposed to Issuer -100% -15,247 0 06 Jan 2026 Direct
Martin H. Huber Jr. MRSN Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -9,573 0 06 Jan 2026 Direct
Martin H. Huber Jr. MRSN Restricted Stock Units Disposed to Issuer -100% -21,924 0 06 Jan 2026 Direct
Martin H. Huber Jr. MRSN Stock Option (right to buy) Disposed to Issuer -100% -87,257 0 06 Jan 2026 Direct
Ashish Mandelia MRSN Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -2,300 0 06 Jan 2026 Direct
Ashish Mandelia MRSN Restricted Stock Units Disposed to Issuer -100% -1,570 0 06 Jan 2026 Direct
Ashish Mandelia MRSN Stock Option (right to buy) Disposed to Issuer -100% -13,602 0 06 Jan 2026 Direct
Anna Protopapas MRSN Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -12,499 0 06 Jan 2026 See footnote
Anna Protopapas MRSN Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -6,721 0 06 Jan 2026 Direct
Anna Protopapas MRSN Stock Option (right to buy) Disposed to Issuer -100% -64,088 0 06 Jan 2026 Direct
Timothy B. Lowinger MRSN Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -10,466 0 06 Jan 2026 Direct
Timothy B. Lowinger MRSN Restricted Stock Units Disposed to Issuer -100% -4,608 0 06 Jan 2026 Direct
Timothy B. Lowinger MRSN Stock Option (right to buy) Disposed to Issuer -100% -43,445 0 06 Jan 2026 Direct
David M. Mott MRSN Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -383 0 06 Jan 2026 See Footnote
David M. Mott MRSN Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -23,546 0 06 Jan 2026 Direct
David M. Mott MRSN Stock Option (right to buy) Disposed to Issuer -100% -12,948 0 06 Jan 2026 Direct
Brian DeSchuytner MRSN Common Stock Disposition pursuant to a tender of shares in a change of control transaction -100% -5,015 0 06 Jan 2026 Direct
Brian DeSchuytner MRSN Restricted Stock Units Disposed to Issuer -100% -5,300 0 06 Jan 2026 Direct
Brian DeSchuytner MRSN Stock Option (right to buy) Disposed to Issuer -100% -50,393 0 06 Jan 2026 Direct
Mohan Bala MRSN Common Stock Sale -2.57% $762 $9.90 -77 2,922 27 Oct 2025 Direct
Mohan Bala MRSN Common Stock Options Exercise 9.09% 250 2,999 25 Oct 2025 Direct
Mohan Bala MRSN Restricted Stock Unit Options Exercise -100% -250 0 25 Oct 2025 Direct
* marks a reported price that did not pass the local price check.
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