SEC ownership of ANAVEX LIFE SCIENCES CORP.

Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0001314052.

Comparable stake leader

VANGUARD CAPITAL MANAGEMENT LLC

Disclosed value leader

BlackRock, Inc.

Comparable rows

50/50

Latest evidence

31 Mar 2026

Top shareholders Insider holders Latest transactions

Public ticker: AVXL on Nasdaq
Parsed ownership sources: 13F, 13D/G, and 3/4/5
Source: Parsed SEC ownership filingsUse: Compare filing families carefully
Largest SEC-reported holder: VANGUARD CAPITAL MANAGEMENT LLC
Ranking: Comparable ownership first, then disclosed value
Comparable ownership rows: 50 of 50
Meaning: Rows with safely comparable ownership %
Latest 13D/G holder: VANGUARD CAPITAL MANAGEMENT LLC
Source: Latest parsed Schedule 13D/G stake
Latest parsed ownership date: 31 Mar 2026
Freshness: Most recent filing date in this holder set
Issuer CIK: 0001314052
Issuer location: New York, NY

Ownership snapshot

Top shareholders of ANAVEX LIFE SCIENCES CORP. (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader

VANGUARD CAPITAL MANAGEME...

Disclosed value leader

BlackRock, Inc.

Comparable rows

50/50

Latest evidence

31 Mar 2026

13F 13D/G 3/4/5 Lead comparable stake: 5% 13D/G row: VANGUARD CAPITAL MANAGEMENT LLC Showing 1-8 of 50 holder rows.

Quick read

VANGUARD CAPITAL MANAGEMENT LLC leads the comparable SEC ownership view at 5%.

50 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens VANGUARD CAPITAL MANAGEMENT LLC's linked filing trail.

Comparable ownership Top 5

VANGUARD CAPITAL MANAGEMENT LLC 5%

Steffen Thomas 0.05%

BlackRock, Inc. 8.2%

STATE STREET CORP 4.9%

TWO SIGMA INVESTMENTS, LP 3.5%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-8 of 50 holder rows

Holder	Evidence	Ownership %	Position	12M Net Δ	As of
VANGUARD CAPITAL MANAGEMENT LLC	13F 13D/G Company · Vanguard Capital Management 13F 13D/G	5% from 13D/G	$11,862,327 3,863,950 shares	—	31 Mar 2026
Steffen Thomas	3/4/5 Director 3/4/5	0.05%	$338,295 43,651 shares	—	05 Jun 2025
BlackRock, Inc.	13F Company 13F	8.2%	$23,361,527 7,609,618 shares	—	31 Mar 2026
STATE STREET CORP	13F Company 13F	4.9%	$13,851,926 4,512,028 shares	—	31 Mar 2026
TWO SIGMA INVESTMENTS, LP	13F Company 13F	3.5%	$9,971,016 3,247,888 shares	—	31 Mar 2026
GEODE CAPITAL MANAGEMENT, LLC	13F Company 13F	2.4%	$6,719,665 2,188,275 shares	—	31 Mar 2026
SUSQUEHANNA INTERNATIONAL GROUP, LLP	13F Company 13F	1.1%	$3,056,685 995,663 shares	—	31 Mar 2026
Summit Financial, LLC	13F Company 13F	1%	$2,887,197 940,455 shares	—	31 Mar 2026

How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Forms 3/4/5 flow

Insider trading overview

Insider buy and sell flow is broadly balanced over the last 12 months. No Buy or Sell transactions have been reported since 09 Aug 2025.

Buys

Insiders: 0

Sells

Insiders: 0

Net

Shares: 0

Window

Last 12 months

4 rolling buckets

Buy value Sell value

Shares: 0 Shares: 0

Window (months)	Buy value	Sell value	Net value
0-3	$0	$0	$0
3-6	$0	$0	$0
6-9	$0	$0	$0
9-12	$0	$0	$0

Reporting owners

Insider holders from Forms 3/4/5

Showing 1-10 of 10 reporting-owner rows connected to ANAVEX LIFE SCIENCES CORP.. Open a relationship link for the CIK-to-CIK filing trail.

Rows

Largest Forms 3/4/5 holder

Christopher U. Missling

Net 12M change

Latest report

04 May 2026

Name	Relationship	Holdings Value	Valuation	Report Date
Christopher U. Missling	President and CEO, Director	$14,467,380	Mixed	06 Jan 2026
Steffen Thomas	Director	$338,295	Mixed	05 Jun 2025
Peter D.o. Donhauser	Director	$18,200	Filing P/S	31 Mar 2025
Elliot Favus	Director		Mixed	21 May 2021
Sandra Boenisch	PFO & Treasurer		Mixed	06 Jan 2026
Claus Vander Velden	Director		Mixed	31 Mar 2025
Axel Paeger	Director		Mixed	23 Feb 2026
Terrie Kellmeyer	Interim CEO		Mixed	04 May 2026
Jiong Ma	Director		Mixed	31 Mar 2025
Athanasios Skarpelos	Director		Mixed	31 Mar 2025

Recent insider transactions for ANAVEX LIFE SCIENCES CORP.

Showing up to 300 recent insider transactions from the last 12 months.

Insider	Symbol	Class	Transaction	%	Shares	Shares owned	Date	Ownership
Christopher U. Missling	AVXL	Stock Option (Right to Buy)	Award		125,000	125,000	06 Jan 2026	Direct
Sandra Boenisch	AVXL	Stock Option (Right to Buy)	Award		12,500	12,500	06 Jan 2026	Direct
Sandra Boenisch	AVXL	Stock Option (Right to Buy)	Award	100%	12,500	25,000	02 Oct 2025	Direct
Christopher U. Missling	AVXL	Stock Option (Right to Buy)	Award	100%	125,000	250,000	02 Oct 2025	Direct
Christopher U. Missling	AVXL	Common Stock	Tax liability	-8.76%	-145,048	1,510,165	11 Sep 2025	Direct
Christopher U. Missling	AVXL	Common Stock	Options Exercise	12.8%	187,500	1,655,213	11 Sep 2025	Direct
Christopher U. Missling	AVXL	Stock Option (Right to Buy)	Options Exercise	-100%	-187,500	0	11 Sep 2025	Direct
Sandra Boenisch	AVXL	Stock Option (Right to Buy)	Award		12,500	12,500	20 Aug 2025	Direct
Christopher U. Missling	AVXL	Stock Option (Right to Buy)	Award		125,000	125,000	20 Aug 2025	Direct

^* marks a reported price that did not pass the local price check.