Comparable stake leader
BlackRock, Inc.
Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0000879407.
Comparable stake leader
BlackRock, Inc.
Disclosed value leader
BlackRock, Inc.
Comparable rows
50/50
Latest evidence
15 Jun 2026
Ownership snapshot
Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.
Quick read
50 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.
Ownership % is shown only when SEC disclosures are safely comparable across share classes.
| Holder | Evidence | Ownership % | Position | 12M Net Δ | As of |
|---|---|---|---|---|---|
| BlackRock, Inc. |
13F
13D/G
Company
|
12%
from 13D/G
|
$1,138,727,235
18,161,519 shares
|
— | 31 Mar 2026 |
| Avoro Capital Advisors LLC |
13F
13D/G
Company
|
8.3%
from 13D/G
|
$670,889,937
10,699,999 shares
|
— | 31 Mar 2026 |
| FMR LLC |
13D/G
13F
Company
|
5.2%
|
$478,720,814
7,349,107 shares
|
$0 | 31 Mar 2026 |
| VANGUARD PORTFOLIO MANAGEMENT LLC |
13D/G
13F
Vanguard Portfolio Management · Company
|
5.2%
|
$455,826,304
7,269,957 shares
|
$0 | 31 Mar 2026 |
| VANGUARD CAPITAL MANAGEMENT LLC |
13D/G
13F
Vanguard Capital Management · Company
|
5%
|
$443,997,071
7,081,293 shares
|
$0 | 31 Mar 2026 |
| STATE STREET CORP |
13F
13D/G
Company · STATE STREET CORPORATION
|
4.6%
from 13D/G
|
$407,307,351
6,496,130 shares
|
— | 31 Mar 2026 |
| Christopher Richard Anzalone |
3/4/5
Chief Executive Officer, Director
|
2.7%
|
$251,799,942
3,792,739 shares
|
-$24,010,564 | 02 Jan 2026 |
| Patrick O'Brien |
3/4/5
COO
|
0.39%
|
$36,342,471
547,408 shares
|
-$3,123,349 | 06 Jan 2026 |
Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. — indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.
Forms 3/4/5 flow
Net insider flow leans to selling over the last 12 months. Net value: -$37,882,496.
| Window (months) | Buy shares | Sell shares | Buy value | Sell value | Net value |
|---|---|---|---|---|---|
| 0-3 | 0 | 26,065 | $0 | $1,912,619 | -$1,912,619 |
| 3-6 | 0 | 164,570 | $0 | $10,747,188 | -$10,747,188 |
| 6-9 | 0 | 376,266 | $0 | $24,197,689 | -$24,197,689 |
| 9-12 | 0 | 40,000 | $0 | $1,025,000 | -$1,025,000 |
Reporting owners
Showing 1-18 of 18 reporting-owner rows connected to ARROWHEAD PHARMACEUTICALS, INC.. Open a relationship link for the CIK-to-CIK filing trail.
| Name | Relationship | Holdings Value | Past Year Net Change | Change % | Valuation | Report Date |
|---|---|---|---|---|---|---|
| Christopher Richard Anzalone | Chief Executive Officer, Director | $251,799,942 | -$24,010,564 | -8.7% | Filing P/S | 02 Jan 2026 |
| Patrick O'Brien | Coo | $36,342,471 | -$3,123,349 | -7.9% | Mixed | 06 Jan 2026 |
| James C. Hamilton | Chief Medical Officer | $17,021,850 | -$5,651,561 | -25% | Filing P/S | 23 Apr 2026 |
| Daniel Joseph Apel | Chief Financial Officer | $11,716,127 | -$934,285 | -7.4% | Filing P/S | 22 Apr 2026 |
| Kenneth Allen Myszkowski | Chief Financial Officer | $8,967,476 | Filing P/S | 04 Jan 2025 | ||
| Javier San Martin | Chief Medical Officer | $7,417,833 | Mixed | 04 Jan 2024 | ||
| Michael S. Perry | Director | $4,977,736 | -$991,738 | -17% | Mixed | 16 Dec 2025 |
| Mauro Ferrari | Director | $4,833,710 | -$1,020,513 | -17% | Filing P/S | 26 Dec 2025 |
| Hongbo Lu | Director | $3,998,682 | -$228,334 | -5.4% | Filing P/S | 12 May 2026 |
| James Hassard | Chief Commercial Officer | $3,951,878 | Mixed | 22 Jun 2021 | ||
| William D. Waddill | Director | $3,876,262 | -$566,038 | -13% | Filing P/S | 19 Dec 2025 |
| Tracie Oliver | Chief Commercial Officer | $3,213,265 | Filing P/S | 02 Jul 2024 | ||
| Douglas B. Given | Director | $2,736,641 | Filing P/S | 16 Dec 2024 | ||
| Victoria Vakiener | Director | $2,443,095 | -$679,491 | -22% | Filing P/S | 19 Dec 2025 |
| Adeoye Y. Olukotun | Director | $2,300,928 | -$676,623 | -23% | Filing P/S | 19 Dec 2025 |
| Douglas S. Ingram | Director | $1,869,396 | Mixed | 16 Dec 2025 | ||
| Marianne de Backer | Director | $1,168,448 | Mixed | 10 Jan 2023 | ||
| Matthew Gregory Cohen | Director | $745,001 | Median | 15 Jun 2026 |
Showing up to 300 recent insider transactions from the last 12 months.
| Insider | Symbol | Class | Transaction | % | SEC-reported value | SEC-reported price | Shares | Shares owned | Date | Ownership |
|---|---|---|---|---|---|---|---|---|---|---|
| Matthew Gregory Cohen | ARWR | Common Stock | Award | 11,882 | 11,882 | 15 Jun 2026 | Direct | |||
| Hongbo Lu | ARWR | Common Stock | Sale | -5.4% | $228,334 | $76.88 | -2,970 | 52,012 | 12 May 2026 | Direct |
| James C. Hamilton | ARWR | Common Stock | Sale | -4.22% | $750,000 | $75.00 | -10,000 | 226,958 | 23 Apr 2026 | Direct |
| Daniel Joseph Apel | ARWR | Common Stock | Sale | -7.44% | $934,285 | $71.35 | -13,095 | 162,905 | 22 Apr 2026 | Direct |
| James C. Hamilton | ARWR | Common Stock | Sale | -4.05% | $641,900 | $64.19 | -10,000 | 236,958 | 05 Mar 2026 | Direct |
| James C. Hamilton | ARWR | Common Stock | Award | 43.6% | 75,000 | 246,958 | 06 Jan 2026 | Direct | ||
| Daniel Joseph Apel | ARWR | Common Stock | Award | 74.1% | 75,000 | 176,200 | 06 Jan 2026 | Direct | ||
| Patrick O'Brien | ARWR | Common Stock | Award | 15.9% | 75,000 | 547,408 | 06 Jan 2026 | Direct | ||
| Patrick O'Brien | ARWR | Common Stock | Gift | -0.53% | -2,500 | 472,408 | 06 Jan 2026 | Direct | ||
| Patrick O'Brien | ARWR | Common Stock | Sale | -9.44% | $3,123,349 | $63.11 | -49,493 | 474,908 | 05 Jan 2026 | Direct |
| James C. Hamilton | ARWR | Common Stock | Sale | -18.9% | $2,534,661 | $63.11 | -40,164 | 171,958 | 05 Jan 2026 | Direct |
| Christopher Richard Anzalone | ARWR | Common Stock | Sale | -0.35% | $871,703 | $66.10 | -13,187 | 3,792,739 | 02 Jan 2026 | Direct |
| Patrick O'Brien | ARWR | Common Stock | Gift | -0.53% | -2,800 | 524,401 | 31 Dec 2025 | Direct | ||
| Christopher Richard Anzalone | ARWR | Common Stock | Sale | -1.34% | $3,575,575 | $69.13 | -51,726 | 3,805,926 | 29 Dec 2025 | Direct |
| Christopher Richard Anzalone | ARWR | Common Stock | Options Exercise | 1.36% | 51,726 | 3,857,652 | 29 Dec 2025 | Direct | ||
| Christopher Richard Anzalone | ARWR | Stock Option (right to buy Common Stock) | Options Exercise | -100% | -51,726 | 0 | 29 Dec 2025 | Direct | ||
| Mauro Ferrari | ARWR | Common Stock | Sale | -9.83% | $527,100 | $70.00 | -7,530 | 69,053 | 26 Dec 2025 | Direct |
| Christopher Richard Anzalone | ARWR | Common Stock | Sale | -0.33% | $861,340 | $68.44 | -12,586 | 3,805,926 | 22 Dec 2025 | Direct |
| William D. Waddill | ARWR | Common Stock | Sale | -12.9% | $566,038 | $67.65 | -8,367 | 56,563 | 19 Dec 2025 | Direct |
| Victoria Vakiener | ARWR | Common Stock | Sale | -21.9% | $679,491 | $67.68 | -10,040 | 35,723 | 19 Dec 2025 | Direct |
| Christopher Richard Anzalone | ARWR | Common Stock | Sale | -0.35% | $909,683 | $67.66 | -13,445 | 3,818,512 | 19 Dec 2025 | Direct |
| Adeoye Y. Olukotun | ARWR | Common Stock | Sale | -22.9% | $676,623 | $67.66 | -10,000 | 33,600 | 19 Dec 2025 | Direct |
| Christopher Richard Anzalone | ARWR | Common Stock | Sale | -2.17% | $5,443,462 | $64.04 | -85,000 | 3,831,957 | 17 Dec 2025 | Direct |
| Mauro Ferrari | ARWR | Common Stock | Award | 11.4% | 7,819 | 76,583 | 16 Dec 2025 | Direct | ||
| Hongbo Lu | ARWR | Common Stock | Award | 16.6% | 7,819 | 54,982 | 16 Dec 2025 | Direct | ||
| Michael S. Perry | ARWR | Common Stock | Award | 6.78% | 7,819 | 123,059 | 16 Dec 2025 | Direct | ||
| Victoria Vakiener | ARWR | Common Stock | Award | 20.6% | 7,819 | 45,763 | 16 Dec 2025 | Direct | ||
| Douglas S. Ingram | ARWR | Common Stock | Award | 20.4% | 7,819 | 46,215 | 16 Dec 2025 | Direct | ||
| Adeoye Y. Olukotun | ARWR | Common Stock | Award | 21.8% | 7,819 | 43,600 | 16 Dec 2025 | Direct | ||
| William D. Waddill | ARWR | Common Stock | Award | 13.7% | 7,819 | 64,930 | 16 Dec 2025 | Direct | ||
| Christopher Richard Anzalone | ARWR | Common Stock | Sale | -1.37% | $3,398,187 | $62.58 | -54,298 | 3,916,957 | 16 Dec 2025 | Direct |
| Christopher Richard Anzalone | ARWR | Common Stock | Sale | -3.17% | $8,950,615 | $68.85 | -130,000 | 3,971,255 | 15 Dec 2025 | Direct |
| Christopher Richard Anzalone | ARWR | Common Stock | Award | 4.59% | 180,000 | 4,101,255 | 12 Dec 2025 | Direct | ||
| Michael S. Perry | ARWR | Common Stock | Sale | -12.4% | $991,738 | $61.03 | -16,250 | 115,240 | 05 Dec 2025 | Direct |
| Mauro Ferrari | ARWR | Common Stock | Sale | -11.3% | $493,412 | $56.39 | -8,750 | 68,764 | 28 Nov 2025 | Direct |
| James C. Hamilton | ARWR | Common Stock | Sale | -8.62% | $700,000 | $35.00 | -20,000 | 212,122 | 01 Oct 2025 | Direct |
| James C. Hamilton | ARWR | Common Stock | Sale | -6.07% | $450,000 | $30.00 | -15,000 | 232,122 | 12 Sep 2025 | Direct |
| James C. Hamilton | ARWR | Common Stock | Sale | -5.72% | $375,000 | $25.00 | -15,000 | 247,122 | 02 Sep 2025 | Direct |
| James C. Hamilton | ARWR | Common Stock | Sale | -3.46% | $187,780 | $20.00 | -9,389 | 262,122 | 15 Aug 2025 | Direct |
| James C. Hamilton | ARWR | Common Stock | Sale | -0.22% | $12,220 | $20.00 | -611 | 271,511 | 13 Aug 2025 | Direct |