SEC ownership of ARROWHEAD PHARMACEUTICALS, INC.

Top holders, 13D/G large-stake signals, insider positions, and transaction flow tied to CIK 0000879407.

Comparable stake leader

BlackRock, Inc.

Disclosed value leader

BlackRock, Inc.

Comparable rows

50/50

Latest evidence

15 Jun 2026

Ownership snapshot CIK-linked ownership evidence from parsed SEC filings. 3 signals
Comparable ownership rows
50 of 50
Meaning: Rows with safely comparable ownership %
Latest 13D/G holder
BlackRock, Inc.
Source: Latest parsed Schedule 13D/G stake
Latest parsed ownership date
15 Jun 2026
Freshness: Most recent filing date in this holder set
Issuer Names, identifiers, and filing context for this profile. 2 identity fields
Issuer CIK
0000879407
Issuer location
Pasadena, CA

Ownership snapshot

Top shareholders of ARROWHEAD PHARMACEUTICALS, INC. (13F + 13D/G + 3/4/5)

Grouped by holder across the latest SEC ownership disclosures. Start with comparable ownership when available, then verify the linked 13F, 13D/G, or 3/4/5 evidence.

Comparable stake leader
BlackRock, Inc.
Disclosed value leader
BlackRock, Inc.
Comparable rows
50/50
Latest evidence
15 Jun 2026
13F 13D/G 3/4/5 Lead comparable stake: 12% 13D/G row: BlackRock, Inc. Showing 1-8 of 50 holder rows.

Quick read

BlackRock, Inc. leads the comparable SEC ownership view at 12%.

50 of 50 rows have a safely comparable ownership percentage. Use this as a filing-backed starting point, then open the detailed table for source links, reporting role, position value, share count, and filing date.

Open SEC evidence Opens BlackRock, Inc.'s linked filing trail.
Comparable ownership Top 5
BlackRock, Inc. 12%
Avoro Capital Advisors LLC 8.3%
FMR LLC 5.2%
VANGUARD PORTFOLIO MANAGEMENT LLC 5.2%
VANGUARD CAPITAL MANAGEMENT LLC 5%

Ownership % is shown only when SEC disclosures are safely comparable across share classes.

Detailed SEC evidence table Showing 1-8 of 50 holder rows
Holder Evidence Ownership % Position 12M Net Δ As of
BlackRock, Inc.
13F 13D/G
Company
12%
from 13D/G
$1,138,727,235
18,161,519 shares
31 Mar 2026
Avoro Capital Advisors LLC
13F 13D/G
Company
8.3%
from 13D/G
$670,889,937
10,699,999 shares
31 Mar 2026
FMR LLC
13D/G 13F
Company
5.2%
$478,720,814
7,349,107 shares
$0 31 Mar 2026
VANGUARD PORTFOLIO MANAGEMENT LLC
13D/G 13F
Vanguard Portfolio Management · Company
5.2%
$455,826,304
7,269,957 shares
$0 31 Mar 2026
VANGUARD CAPITAL MANAGEMENT LLC
13D/G 13F
Vanguard Capital Management · Company
5%
$443,997,071
7,081,293 shares
$0 31 Mar 2026
STATE STREET CORP
13F 13D/G
Company · STATE STREET CORPORATION
4.6%
from 13D/G
$407,307,351
6,496,130 shares
31 Mar 2026
Christopher Richard Anzalone
3/4/5
Chief Executive Officer, Director
2.7%
$251,799,942
3,792,739 shares
-$24,010,564 02 Jan 2026
Patrick O'Brien
3/4/5
COO
0.39%
$36,342,471
547,408 shares
-$3,123,349 06 Jan 2026
How to read this table

Rows are grouped by holder and ranked first by SEC-reported ownership % when it is safely comparable, then by disclosed holdings value. indicates unavailable or non-comparable values; "mixed-class rows" means the latest filing spans non-comparable classes.

Forms 3/4/5 flow

Insider trading overview

Net insider flow leans to selling over the last 12 months. Net value: -$37,882,496.

Buys
$0
Insiders: 0
Sells
$37,882,496
Insiders: 10
Net
-$37,882,496
Shares: -606,901
Window
Last 12 months
4 rolling buckets
Buy value Sell value
Shares: 0 Shares: 606,901
Window (months) Buy shares Sell shares Buy value Sell value Net value
0-3 0 26,065 $0 $1,912,619 -$1,912,619
3-6 0 164,570 $0 $10,747,188 -$10,747,188
6-9 0 376,266 $0 $24,197,689 -$24,197,689
9-12 0 40,000 $0 $1,025,000 -$1,025,000

Reporting owners

Insider holders from Forms 3/4/5

Showing 1-18 of 18 reporting-owner rows connected to ARROWHEAD PHARMACEUTICALS, INC.. Open a relationship link for the CIK-to-CIK filing trail.

Rows
18
Largest Forms 3/4/5 holder
Christopher Richard Anzalone
Net 12M change
-$37,882,496
Latest report
15 Jun 2026
Name Relationship Holdings Value Past Year Net Change Change % Valuation Report Date
Christopher Richard Anzalone Chief Executive Officer, Director $251,799,942 -$24,010,564 -8.7% Filing P/S 02 Jan 2026
Patrick O'Brien Coo $36,342,471 -$3,123,349 -7.9% Mixed 06 Jan 2026
James C. Hamilton Chief Medical Officer $17,021,850 -$5,651,561 -25% Filing P/S 23 Apr 2026
Daniel Joseph Apel Chief Financial Officer $11,716,127 -$934,285 -7.4% Filing P/S 22 Apr 2026
Kenneth Allen Myszkowski Chief Financial Officer $8,967,476 Filing P/S 04 Jan 2025
Javier San Martin Chief Medical Officer $7,417,833 Mixed 04 Jan 2024
Michael S. Perry Director $4,977,736 -$991,738 -17% Mixed 16 Dec 2025
Mauro Ferrari Director $4,833,710 -$1,020,513 -17% Filing P/S 26 Dec 2025
Hongbo Lu Director $3,998,682 -$228,334 -5.4% Filing P/S 12 May 2026
James Hassard Chief Commercial Officer $3,951,878 Mixed 22 Jun 2021
William D. Waddill Director $3,876,262 -$566,038 -13% Filing P/S 19 Dec 2025
Tracie Oliver Chief Commercial Officer $3,213,265 Filing P/S 02 Jul 2024
Douglas B. Given Director $2,736,641 Filing P/S 16 Dec 2024
Victoria Vakiener Director $2,443,095 -$679,491 -22% Filing P/S 19 Dec 2025
Adeoye Y. Olukotun Director $2,300,928 -$676,623 -23% Filing P/S 19 Dec 2025
Douglas S. Ingram Director $1,869,396 Mixed 16 Dec 2025
Marianne de Backer Director $1,168,448 Mixed 10 Jan 2023
Matthew Gregory Cohen Director $745,001 Median 15 Jun 2026

Recent insider transactions for ARROWHEAD PHARMACEUTICALS, INC.

Showing up to 300 recent insider transactions from the last 12 months.

Insider Symbol Class Transaction % SEC-reported value SEC-reported price Shares Shares owned Date Ownership
Matthew Gregory Cohen ARWR Common Stock Award 11,882 11,882 15 Jun 2026 Direct
Hongbo Lu ARWR Common Stock Sale -5.4% $228,334 $76.88 -2,970 52,012 12 May 2026 Direct
James C. Hamilton ARWR Common Stock Sale -4.22% $750,000 $75.00 -10,000 226,958 23 Apr 2026 Direct
Daniel Joseph Apel ARWR Common Stock Sale -7.44% $934,285 $71.35 -13,095 162,905 22 Apr 2026 Direct
James C. Hamilton ARWR Common Stock Sale -4.05% $641,900 $64.19 -10,000 236,958 05 Mar 2026 Direct
James C. Hamilton ARWR Common Stock Award 43.6% 75,000 246,958 06 Jan 2026 Direct
Daniel Joseph Apel ARWR Common Stock Award 74.1% 75,000 176,200 06 Jan 2026 Direct
Patrick O'Brien ARWR Common Stock Award 15.9% 75,000 547,408 06 Jan 2026 Direct
Patrick O'Brien ARWR Common Stock Gift -0.53% -2,500 472,408 06 Jan 2026 Direct
Patrick O'Brien ARWR Common Stock Sale -9.44% $3,123,349 $63.11 -49,493 474,908 05 Jan 2026 Direct
James C. Hamilton ARWR Common Stock Sale -18.9% $2,534,661 $63.11 -40,164 171,958 05 Jan 2026 Direct
Christopher Richard Anzalone ARWR Common Stock Sale -0.35% $871,703 $66.10 -13,187 3,792,739 02 Jan 2026 Direct
Patrick O'Brien ARWR Common Stock Gift -0.53% -2,800 524,401 31 Dec 2025 Direct
Christopher Richard Anzalone ARWR Common Stock Sale -1.34% $3,575,575 $69.13 -51,726 3,805,926 29 Dec 2025 Direct
Christopher Richard Anzalone ARWR Common Stock Options Exercise 1.36% 51,726 3,857,652 29 Dec 2025 Direct
Christopher Richard Anzalone ARWR Stock Option (right to buy Common Stock) Options Exercise -100% -51,726 0 29 Dec 2025 Direct
Mauro Ferrari ARWR Common Stock Sale -9.83% $527,100 $70.00 -7,530 69,053 26 Dec 2025 Direct
Christopher Richard Anzalone ARWR Common Stock Sale -0.33% $861,340 $68.44 -12,586 3,805,926 22 Dec 2025 Direct
William D. Waddill ARWR Common Stock Sale -12.9% $566,038 $67.65 -8,367 56,563 19 Dec 2025 Direct
Victoria Vakiener ARWR Common Stock Sale -21.9% $679,491 $67.68 -10,040 35,723 19 Dec 2025 Direct
Christopher Richard Anzalone ARWR Common Stock Sale -0.35% $909,683 $67.66 -13,445 3,818,512 19 Dec 2025 Direct
Adeoye Y. Olukotun ARWR Common Stock Sale -22.9% $676,623 $67.66 -10,000 33,600 19 Dec 2025 Direct
Christopher Richard Anzalone ARWR Common Stock Sale -2.17% $5,443,462 $64.04 -85,000 3,831,957 17 Dec 2025 Direct
Mauro Ferrari ARWR Common Stock Award 11.4% 7,819 76,583 16 Dec 2025 Direct
Hongbo Lu ARWR Common Stock Award 16.6% 7,819 54,982 16 Dec 2025 Direct
Michael S. Perry ARWR Common Stock Award 6.78% 7,819 123,059 16 Dec 2025 Direct
Victoria Vakiener ARWR Common Stock Award 20.6% 7,819 45,763 16 Dec 2025 Direct
Douglas S. Ingram ARWR Common Stock Award 20.4% 7,819 46,215 16 Dec 2025 Direct
Adeoye Y. Olukotun ARWR Common Stock Award 21.8% 7,819 43,600 16 Dec 2025 Direct
William D. Waddill ARWR Common Stock Award 13.7% 7,819 64,930 16 Dec 2025 Direct
Christopher Richard Anzalone ARWR Common Stock Sale -1.37% $3,398,187 $62.58 -54,298 3,916,957 16 Dec 2025 Direct
Christopher Richard Anzalone ARWR Common Stock Sale -3.17% $8,950,615 $68.85 -130,000 3,971,255 15 Dec 2025 Direct
Christopher Richard Anzalone ARWR Common Stock Award 4.59% 180,000 4,101,255 12 Dec 2025 Direct
Michael S. Perry ARWR Common Stock Sale -12.4% $991,738 $61.03 -16,250 115,240 05 Dec 2025 Direct
Mauro Ferrari ARWR Common Stock Sale -11.3% $493,412 $56.39 -8,750 68,764 28 Nov 2025 Direct
James C. Hamilton ARWR Common Stock Sale -8.62% $700,000 $35.00 -20,000 212,122 01 Oct 2025 Direct
James C. Hamilton ARWR Common Stock Sale -6.07% $450,000 $30.00 -15,000 232,122 12 Sep 2025 Direct
James C. Hamilton ARWR Common Stock Sale -5.72% $375,000 $25.00 -15,000 247,122 02 Sep 2025 Direct
James C. Hamilton ARWR Common Stock Sale -3.46% $187,780 $20.00 -9,389 262,122 15 Aug 2025 Direct
James C. Hamilton ARWR Common Stock Sale -0.22% $12,220 $20.00 -611 271,511 13 Aug 2025 Direct
* marks a reported price that did not pass the local price check.
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