| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 12.1% | 25.4M | 0 | 25.4M | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 10.3% | 21.6M | 0 | 21.6M | Kristin Mariani | Head of North America Compliance, CCO |