| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 10.5% | 3.86M | 0 | 3.86M | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 9.1% | 3.36M | 0 | 3.36M | Kristin Mariani | Head of North America Compliance, CCO |