| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 10.5% | 3,862,551 | 0 | 3,862,551 | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 9.1% | 3,356,076 | 0 | 3,356,076 | Kristin Mariani | Head of North America Compliance, CCO |