| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| JANUS HENDERSON GROUP PLC | 14.6% | 14,080,219 | 0 | 14,080,219 | Kristin Mariani | Head of North America Compliance, CCO | |
| Janus Henderson Biotech Innovation Master Fund Ltd | 5.4% | 5,203,295 | 0 | 5,203,295 | Kristin Mariani | Head of North America Compliance, CCO |