Quick Takeaways
- TANG CAPITAL MANAGEMENT LLC filed SCHEDULE 13G/A for Spyre Therapeutics, Inc. Common Stock, par value $0.0001 per share (SYRE).
- Disclosed ownership: 2.4%.
- Date of event: 31 Dec 2025.
TANG CAPITAL MANAGEMENT LLC - 31 Dec 2025 SCHEDULE 13G/A Report for Spyre Therapeutics, Inc. Common Stock, par value $0.0001 per share (SYRE)
- Filing Manager
- TANG CAPITAL MANAGEMENT LLC
- Reporting Manager
- TANG CAPITAL MANAGEMENT, LLC
- Symbol
- SYRE
- Shares outstanding
- 78,841,667 shares
- Disclosed Ownership
- 1,892,200 shares
- Ownership
- 2.4%
- Form type
- SCHEDULE 13G/A
- Filing time
- 17 Feb 2026, 16:15:06 UTC
- Date of event
- 31 Dec 2025
- Previous filing
- 01 May 2025
- SEC
- View on sec.gov
Quoteable Key Fact
"TANG CAPITAL MANAGEMENT LLC disclosed 2.4% ownership in Spyre Therapeutics, Inc. Common Stock, par value $0.0001 per share (SYRE) on 31 Dec 2025."
What Changed
- Previous schedule filing date: 01 May 2025.
- Current filing was accepted on 17 Feb 2026, 16:15.
Why This Matters
- This page explains what this Schedule 13D/13G filing tells you before manager-level rows.
- You can verify ownership claims directly against the original SEC filing.
Official SEC Source
Backed by Schedule 13D/13G
Beneficial ownership values are sourced from the original SEC Schedule 13D/13G filing.
See Original FilingReporting Managers (6)
| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| TANG CAPITAL MANAGEMENT, LLC | 2.4% | 1,892,200 | 0 | 1,892,200 | /s/ Kevin Tang | Manager | |
| KEVIN TANG | 2.4% | 1,892,200 | 0 | 1,892,200 | /s/ Kevin Tang | Self | |
| TANG CAPITAL PARTNERS, LP | 1.3% | 1,012,338 | 0 | 1,012,338 | /s/ Kevin Tang | Manager, Tang Capital Management, LLC, General Partner | |
| TANG CAPITAL PARTNERS INTERNATIONAL, LP | 1.1% | 879,862 | 0 | 879,862 | /s/ Kevin Tang | Manager, Tang Capital Management, LLC, General Partner | |
| TANG CAPITAL PARTNERS III, INC | 0% | 0 | 0 | 0 | /s/ Kevin Tang | Chief Executive Officer | |
| TANG CAPITAL PARTNERS IV, INC | 0% | 0 | 0 | 0 | /s/ Kevin Tang | Chief Executive Officer |