| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| Octagon Capital Advisors LP | 4.7% | 1,000,000 | 0 | 1,000,000 | /s/ Ting Jia | Managing Member | |
| Octagon Investments Master Fund LP | 3% | 650,000 | 0 | 650,000 | /s/ Ting Jia | Managing Member, Octagon Investments GP, LLC, its general partner | |
| Octagon Biotech Opportunities Fund I LP | 1.7% | 350,000 | 0 | 350,000 | /s/ Ting Jia | Managing Member, Octagon Investments GP, LLC, its general partner | |
| Ting Jia | 4.7% | 1,000,000 | 0 | 1,000,000 | /s/ Ting Jia | Ting Jia |