BAKER BROS. ADVISORS LP - 31 Dec 2025 SCHEDULE 13G/A Report for Monte Rosa Therapeutics, Inc. Common Stock, par value $0.0001 per share (GLUE)

Filing Manager: BAKER BROS. ADVISORS LP
Reporting Manager: Baker Bros. Advisors LP
Security: Monte Rosa Therapeutics, Inc. Common Stock, par value $0.0001 per share
Symbol: GLUE
Shares outstanding: 64,861,731 shares
Disclosed Ownership: 4,345,736 shares
Ownership: 6.7%
Form type: SCHEDULE 13G/A
Filing time: 17 Feb 2026, 16:10:26 UTC
Date of event: 31 Dec 2025
SEC: View on sec.gov

Reporting Managers (4)

Name	Ownership	Shares Owned	sole voting power	Signature	Title
Baker Bros. Advisors LP	6.7%	4,345,736	4,345,736	/s/ Scott L. Lessing	Scott L. Lessing/ President
Baker Bros. Advisors (GP) LLC	6.7%	4,345,736	4,345,736	/s/ Scott L. Lessing	Scott L. Lessing/ President
Julian C. Baker	6.7%	4,345,736	4,345,736	/s/ Julian C. Baker	Julian C. Baker
Felix J. Baker	6.7%	4,345,736	4,345,736	/s/ Felix J. Baker	Felix J. Baker