HBM Healthcare Investments (Cayman) Ltd. - 30 Sep 2025 SCHEDULE 13G/A Report for Upstream Bio, Inc. Common Stock, par value $0.001 per share (UPB)

Filing Manager
HBM Healthcare Investments (Cayman) Ltd.
Reporting Manager
HBM Healthcare Investments (Cayman) Ltd.
Security
Upstream Bio, Inc. Common Stock, par value $0.001 per share
Symbol
UPB
Shares outstanding
53,539,293 shares
Disclosed Ownership
2,195,111 shares
Ownership
4.1%
Form type
SCHEDULE 13G/A
Filing time
14 Nov 2025, 16:05:34 UTC
Date of event
30 Sep 2025
Previous filing
13 Feb 2025
SEC
View on sec.gov

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Quoteable Key Fact

"HBM Healthcare Investments (Cayman) Ltd. disclosed 4.1% ownership in Upstream Bio, Inc. Common Stock, par value $0.001 per share (UPB) on 30 Sep 2025."

Quick Takeaways

  • HBM Healthcare Investments (Cayman) Ltd. filed SCHEDULE 13G/A for Upstream Bio, Inc. Common Stock, par value $0.001 per share (UPB).
  • Disclosed ownership: 4.1%.
  • Date of event: 30 Sep 2025.

What Changed

  • Previous schedule filing date: 13 Feb 2025.
  • Current filing was accepted on 14 Nov 2025, 16:05.

Why This Matters

  • This page explains what this Schedule 13D/13G filing tells you before manager-level rows.
  • You can verify ownership claims directly against the original SEC filing.

Official SEC Source

Backed by Schedule 13D/13G

Beneficial ownership values are sourced from the original SEC Schedule 13D/13G filing.

See Original Filing

Reporting Managers (1)

Name Ownership Shares Owned sole voting power shared voting power Signature Title CIK
HBM Healthcare Investments (Cayman) Ltd. 4.1% 2,195,111 2,195,111 0 /s/ Jean-Marc LeSieur Jean-Marc LeSieur, Managing Director

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