Fairmount Funds Management LLC - 15 Oct 2025 SCHEDULE 13D/A Report for SPYRE THERAPEUTICS, INC. Common Stock, $0.0001 par value (SYRE)

Filing Manager
Fairmount Funds Management LLC
Reporting Manager
Peter Evan Harwin
Security
SPYRE THERAPEUTICS, INC. Common Stock, $0.0001 par value
Symbol
SYRE
Shares outstanding
81,149,970 shares
Disclosed Ownership
8,106,882 shares
Ownership
10%
Form type
SCHEDULE 13D/A
Filing time
17 Oct 2025, 17:00:44 UTC
Date of event
15 Oct 2025
SEC
View on sec.gov

Reporting Managers (4)

Name Ownership Shares Owned sole voting power shared voting power Signature Title CIK
Fairmount Funds Management LLC 9% 7,272,341 0 7,272,341 /s/ Peter Harwin Peter Harwin, Managing Member 0001802528
Fairmount Healthcare Fund II L.P. 9% 7,272,341 0 7,272,341 /s/ Peter Harwin Peter Harwin, Managing Member 0001769651
Peter Evan Harwin 10% 8,106,882 507,861 7,599,021 /s/ Peter Harwin Peter Harwin 0001663607
Tomas Kiselak 10% 8,106,882 507,861 7,599,021 /s/ Tomas Kiselak Tomas Kiselak 0001830177