| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| ACUTA CAPITAL PARTNERS, LLC | 7.5% | 1,849,402 | 0 | 1,849,402 | /s/ Scott R. Smith | Chief Operating Officer | 0001582844 |
| Anupam Dalal | 7.8% | 1,921,297 | 71,895 | 1,849,402 | /s/ Anupam Dalal | Reporting person | 0001602474 |
| Acuta Capital Fund, LP | 6.4% | 1,572,698 | 0 | 1,572,698 | /s/ Scott R. Smith | Chief Operating Officer of the General Partner, Acuta Capital Partners, LLC | 0001601391 |