VANGUARD GROUP INC - 30 Jun 2025 SCHEDULE 13G Report for Spyre Therapeutics Inc Common Stock (SYRE)

Filing Manager: VANGUARD GROUP INC
Reporting Manager: The Vanguard Group
Security: Spyre Therapeutics Inc Common Stock
Symbol: SYRE
Shares outstanding: 60,365,866 shares
Disclosed Ownership: 3,066,586 shares
Ownership: 5.1%
Form type: SCHEDULE 13G
Filing time: 29 Jul 2025, 14:40:47 UTC
Date of event: 30 Jun 2025
SEC: View on sec.gov

Reporting Managers (1)

Name	Ownership	Shares Owned	sole voting power	shared voting power	Signature	Title	CIK
The Vanguard Group	5.1%	3,066,586	0	47,487	Ashley Grim	Head of Global Fund Administration