| Name | Ownership | Shares Owned | sole voting power | shared voting power | Signature | Title | CIK |
|---|---|---|---|---|---|---|---|
| Sands Capital Life Sciences Pulse Fund II. L.P. | 7.3% | 3,154,409 | 0 | 3,154,409 | /s/ Jonathan Goodman | Jonathan Goodman/General Counsel | |
| Sands Capital Ventures, LLC | 7.3% | 3,154,409 | 0 | 3,154,409 | /s/ Jonathan Goodman | Jonathan Goodman/General Counsel | |
| Frank M. Sands | 7.3% | 3,154,409 | 0 | 3,154,409 | /s/ Frank M. Sands | Frank M. Sands |