Asif Ali - 26 Mar 2026 Form 4 Insider Report for Protagonist Therapeutics, Inc (PTGX)

Reporting relationship: Chief Financial Officer
Issuer ticker: PTGX
Reported as of: 26 Mar 2026
Net transaction value: -$2,581,504
SEC form: 4
Accepted by SEC: 27 Mar 2026, 19:33:56 UTC
Prior SEC filing: 27 Jan 2026
Next SEC filing: 21 Apr 2026
Source filing: View source filing
Reporting owner signature: /s/ Matthew Gosling, Attorney-in-Fact for Asif Ali

Key filing fact

Asif Ali filed Form 4 for Protagonist Therapeutics, Inc (PTGX) on 27 Mar 2026.

Key facts

This page summarizes Asif Ali's Form 4 filing for Protagonist Therapeutics, Inc (PTGX).
5 reported transactions and 2 derivative rows are listed below.
Accepted by SEC: 27 Mar 2026, 19:33.

Change

Previous filing in this sequence was filed on 27 Jan 2026.
Current net transaction value: -$2,581,504.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001921163 Primary reporting owner

Ali Asif

Relationship: Chief Financial Officer
Address: C/O PROTAGONIST THERAPEUTICS, INC., 7707 GATEWAY BLVD., SUITE 140, NEWARK
Signature: /s/ Matthew Gosling, Attorney-in-Fact for Asif Ali
Signature date: 27 Mar 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

PTGX transaction

Common Stock

Options Exercise

Transaction value
Shares: +19,500
Change %: +32%
Price: $19.19^*
Shares after: 80,253
Date: 26 Mar 2026
Ownership: Direct
Footnotes: F1

PTGX transaction

Common Stock

Options Exercise

Transaction value
Shares: +5,265
Change %: +6.6%
Price: $12.17^*
Shares after: 85,518
Date: 26 Mar 2026
Ownership: Direct

PTGX transaction

Common Stock

Sale

Transaction value: $2,581,504
Shares: -24,765
Change %: -29%
Price: $104.24
Shares after: 60,753
Date: 26 Mar 2026
Ownership: Direct
Footnotes: F2

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

PTGX transaction Derivative

Stock Option (right to buy)

Options Exercise

Transaction value
Shares: -19,500
Change %: -38%
Price: $0.000000^*
Shares after: 31,300
Date: 26 Mar 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 19,500
Exercise price: $19.19
Footnotes: F3

PTGX transaction Derivative

Stock Option (right to buy)

Options Exercise

Transaction value
Shares: -5,265
Change %: -28%
Price: $0.000000^*
Shares after: 13,282
Date: 26 Mar 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 5,265
Exercise price: $12.17
Footnotes: F4

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 4 footnotes

Footnote F1

Includes an aggregate of 433 shares acquired by the Reporting Person under the Issuer's 2016 Employee Stock Purchase Plan on March 9, 2026.

Footnote F2

The price reported represents the weighted average sale price per share. The shares were sold in multiple transactions at prices ranging from $104.00 to $104.465. Upon request by the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, the Reporting Person will provide full information regarding the number of shares sold at each separate price.

Footnote F3

The stock option was granted to the Reporting Person on April 18, 2022, one quarter vested on April 18, 2023 and the remaining three quarters vest in equal monthly installments through April 18, 2026, subject to the Reporting Person's continued service to the Issuer.

Footnote F4

The stock option was granted to the Reporting Person on January 16, 2023 and vests in 48 equal monthly installments following the date of grant, subject to the Reporting Person's continued service to the Issuer.