Orlov S. Nicole Schaeffer - 02 Jan 2026 Form 4 Insider Report for INSMED Inc (INSM)

Source evidence Original filing metadata and source links for verification. 4 source fields
SEC form
4
Accepted by SEC
06 Jan 2026, 16:03:21 UTC
Prior SEC filing
14 Nov 2025
Source filing
View source filing
Reporting owner 1 detail
Reporting owner signature
/s/ S. Nicole Schaeffer, by Michael A. Smith as Attorney-in-fact

Key filing fact

Orlov S. Nicole Schaeffer filed Form 4 for INSMED Inc (INSM) on 06 Jan 2026.

Key facts

  • This page summarizes Orlov S. Nicole Schaeffer's Form 4 filing for INSMED Inc (INSM).
  • 9 reported transactions and 2 derivative rows are listed below.
  • Accepted by SEC: 06 Jan 2026, 16:03.

Change

  • Previous filing in this sequence was filed on 14 Nov 2025.
  • Current net transaction value: -$14,079,218.

Research use

  • This tells you what this filing adds before you inspect full transaction and derivative tables.
  • You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001401017 Primary reporting owner

Schaeffer Orlov S Nicole

Relationship
Chief People Strategy Officer
Address
700 US HIGHWAY 202/206, BRIDGEWATER
Signature
/s/ S. Nicole Schaeffer, by Michael A. Smith as Attorney-in-fact
Signature date
06 Jan 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

INSM transaction

Common Stock

Award

Transaction value
Shares
+5,293
Change %
+15%
Price
Shares after
41,754
Date
02 Jan 2026
Ownership
Direct
Footnotes
F1, F2
INSM transaction

Common Stock

Options Exercise

Transaction value
$1,214,204
Shares
+87,290
Change %
+209%
Price
$13.91
Shares after
129,044
Date
02 Jan 2026
Ownership
Direct
Footnotes
F3
INSM transaction

Common Stock

Sale

Transaction value
$5,407,908
Shares
-31,030
Change %
-24%
Price
$174.28
Shares after
98,014
Date
02 Jan 2026
Ownership
Direct
Footnotes
F3, F4
INSM transaction

Common Stock

Sale

Transaction value
$5,973,823
Shares
-34,103
Change %
-35%
Price
$175.17
Shares after
63,911
Date
02 Jan 2026
Ownership
Direct
Footnotes
F3, F5
INSM transaction

Common Stock

Sale

Transaction value
$2,259,459
Shares
-12,832
Change %
-20%
Price
$176.08
Shares after
51,079
Date
02 Jan 2026
Ownership
Direct
Footnotes
F3, F6
INSM transaction

Common Stock

Sale

Transaction value
$1,616,676
Shares
-9,125
Change %
-18%
Price
$177.17
Shares after
41,954
Date
02 Jan 2026
Ownership
Direct
Footnotes
F3, F7
INSM transaction

Common Stock

Sale

Transaction value
$35,556
Shares
-200
Change %
-0.48%
Price
$177.78
Shares after
41,754
Date
02 Jan 2026
Ownership
Direct
Footnotes
F3, F8

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

INSM transaction Derivative

Stock Option (right to buy)

Award

Transaction value
$0
Shares
+27,600
Change %
Price
$0.000000
Shares after
27,600
Date
02 Jan 2026
Ownership
Direct
Underlying class
Common Stock
Underlying amount
27,600
Exercise price
$177.12
Footnotes
F9
INSM transaction Derivative

Stock Option (right to buy)

Options Exercise

Transaction value
$0
Shares
-87,290
Change %
-100%
Price
$0.000000
Shares after
0
Date
02 Jan 2026
Ownership
Direct
Underlying class
Common Stock
Underlying amount
87,290
Exercise price
$13.91
Footnotes
F3, F10
* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Rule 10b5-1 trading plan

These transactions were reported as open-market trades under a Rule 10b5-1 plan. The plan lets an insider set trading instructions in advance, which can reduce the risk of trading while in possession of material nonpublic information.

Original filing language: transaction made pursuant to a contract, instruction, or written plan intended to satisfy Rule 10b5-1(c).

Explanation of responses 10 footnotes

Footnote F1

Represents Restricted Stock Units (RSUs), each representing a contingent right to receive one share of Common Stock, granted pursuant to the Company's Amended and Restated 2019 Incentive Plan, as amended. The RSUs vest as follows: 25% on the first day of the first month following the first anniversary of the date of grant (the Initial Vesting Date) and 25% on each anniversary of the Initial Vesting Date until fully vested.

Footnote F2

Each RSU was granted on January 2, 2026 for no consideration.

Footnote F3

This transaction was effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on August 29, 2025 in accordance with Rule 10b5-1 of the Securities Exchange Act of 1934, as amended.

Footnote F4

This is the weighted average sales price representing 31,030 shares sold at prices ranging from $173.67 to $174.66 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Footnote F5

This is the weighted average sales price representing 34,103 shares sold at prices ranging from $174.67 to $175.65 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Footnote F6

This is the weighted average sales price representing 12,832 shares sold at prices ranging from $175.67 to $176.62 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Footnote F7

This is the weighted average sales price representing 9,125 shares sold at prices ranging from $176.68 to $177.67 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Footnote F8

This is the weighted average sales price representing 200 shares sold at prices ranging from $177.72 to $177.84 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.

Footnote F9

These stock options were granted under the Company's Amended and Restated 2019 Incentive Plan, as amended. The options become exercisable based on the following vesting schedule: 25% vest on the Initial Vesting Date and an additional 12.5% vest every six months thereafter until fully vested.

Footnote F10

The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant.

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