Orlov S. Nicole Schaeffer - 12 Nov 2025 Form 4 Insider Report for INSMED Inc (INSM)

Role
Chief People Strategy Officer
Signature
/s/ S. Nicole Schaeffer, by Michael A. Smith as Attorney-in-fact
Issuer symbol
INSM
Transactions as of
12 Nov 2025
Net transactions value
-$5,026,261
Form type
4
Filing time
14 Nov 2025, 16:12:56 UTC
Previous filing
15 Sep 2025
Next filing
06 Jan 2026
SEC
View on sec.gov

Reporting Owners (1)

Name Relationship Address Signature Signature date CIK
Schaeffer Orlov S Nicole Chief People Strategy Officer 700 US HIGHWAY 202/206, BRIDGEWATER /s/ S. Nicole Schaeffer, by Michael A. Smith as Attorney-in-fact 14 Nov 2025 0001401017

Transactions Table

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Ownership Footnotes
transaction INSM Common Stock Options Exercise $793,800 +30,000 +82% $26.46 66,461 12 Nov 2025 Direct
transaction INSM Common Stock Sale $784,811 -4,078 -6.1% $192.45 62,383 12 Nov 2025 Direct F1
transaction INSM Common Stock Sale $1,273,183 -6,575 -11% $193.64 55,808 12 Nov 2025 Direct F2
transaction INSM Common Stock Sale $3,729,943 -19,183 -34% $194.44 36,625 12 Nov 2025 Direct F3
transaction INSM Common Stock Sale $32,124 -164 -0.45% $195.88 36,461 12 Nov 2025 Direct F4

Derivative Securities (e.g., puts, calls, warrants, options, convertible securities)

Type Sym Class Transaction Value $ Shares Change % * Price $ Shares After Date Underlying Class Amount Exercise Price Ownership Footnotes
transaction INSM Stock Option (right to buy) Options Exercise $0 -30,000 -66% $0.000000 15,760 12 Nov 2025 Common Stock 30,000 $26.46 Direct F5
* An asterisk sign (*) next to the price indicates that the price is likely invalid.

Explanation of Responses:

Id Content
F1 This is the weighted average sales price representing 4,078 shares sold at prices ranging from $192.00 to $192.95 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.
F2 This is the weighted average sales price representing 6,575 shares sold at prices ranging from $193.02 to $194.01 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.
F3 This is the weighted average sales price representing 19,183 shares sold at prices ranging from $194.02 to $194.95 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.
F4 This is the weighted average sales price representing 164 shares sold at prices ranging from $195.42 to $195.96 per share. The Reporting Person undertakes to provide to the SEC staff, the issuer, or a security holder of the issuer the number of shares sold at each price within the price range upon request.
F5 The options became exercisable based on the following vesting schedule: 25% vested on the first anniversary of the grant date and an additional 12.5% vested on each sixth month anniversary date thereafter through the fourth anniversary of the date of grant. All options are currently exercisable.