Michael B. Hoffman - 08 Dec 2025 Form 4 Insider Report for Annovis Bio, Inc. (ANVS)

Reporting relationship: Director
Issuer ticker: ANVS
Reported as of: 08 Dec 2025
Net transaction value: +$193,794
SEC form: 4
Accepted by SEC: 08 Dec 2025, 20:05:14 UTC
Prior SEC filing: 25 Nov 2025
Next SEC filing: 03 Apr 2026
Source filing: View source filing
Reporting owner signature: /s/ Maria Maccecchini Attorney-in-Fact

Key filing fact

Michael B. Hoffman filed Form 4 for Annovis Bio, Inc. (ANVS) on 08 Dec 2025.

Key facts

This page summarizes Michael B. Hoffman's Form 4 filing for Annovis Bio, Inc. (ANVS).
2 reported transactions and 0 derivative rows are listed below.
Accepted by SEC: 08 Dec 2025, 20:05.

Change

Previous filing in this sequence was filed on 25 Nov 2025.
Current net transaction value: +$193,794.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001290208 Primary reporting owner

Hoffman Michael B

Relationship: Director
Address: C/O ANNOVIS BIO, INC., 101 LINDENWOOD DR, SUITE 225, MALVERN
Signature: /s/ Maria Maccecchini Attorney-in-Fact
Signature date: 08 Dec 2025

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

ANVS transaction

Common Stock

Purchase

Transaction value: $130,194
Shares: +30,000
Change %: +1.2%
Price: $4.34
Shares after: 2,559,739
Date: 08 Dec 2025
Ownership: Direct

ANVS transaction

Common Stock

Purchase

Transaction value: $63,600
Shares: +15,000
Change %: +0.59%
Price: $4.24
Shares after: 2,574,739
Date: 08 Dec 2025
Ownership: Direct

ANVS holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 223,357
Date: 08 Dec 2025
Ownership: The 2018 Jane and Michael Hoffman Descendants Trust
Footnotes: F1

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 1 footnote

Footnote F1

The shares are held in a family trust formed by the reporting person and the reporting person has voting and investment power over such shares.

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