| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Hoffman Michael B | Director | C/O ANNOVIS BIO, INC., 101 LINDENWOOD DR, SUITE 225, MALVERN | /s/ Maria Maccecchini Attorney-in-Fact | 25 Nov 2025 | 0001290208 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | ANVS | Common Stock | Purchase | $6,150 | +1,489 | +0.06% | $4.13 | 2,482,028 | 24 Nov 2025 | Direct | |
| transaction | ANVS | Common Stock | Purchase | $35,420 | +9,200 | +0.37% | $3.85 | 2,491,228 | 24 Nov 2025 | Direct | |
| transaction | ANVS | Common Stock | Purchase | $1,718 | +415 | +0.02% | $4.14 | 2,491,643 | 24 Nov 2025 | Direct | |
| transaction | ANVS | Common Stock | Purchase | $116,598 | +28,096 | +1.1% | $4.15 | 2,519,739 | 24 Nov 2025 | Direct | |
| holding | ANVS | Common Stock | 223,357 | 24 Nov 2025 | The 2018 Jane and Michael Hoffman Descendants Trust | F1 |
| Id | Content |
|---|---|
| F1 | The shares are held in a family trust formed by the reporting person and the reporting person has voting and investment power over such shares. |