Richard S. Geary - 05 Nov 2025 Form 4 Insider Report for IONIS PHARMACEUTICALS INC (IONS)

Source evidence Original filing metadata and source links for verification. 4 source fields
SEC form
4
Accepted by SEC
07 Nov 2025, 17:12:44 UTC
Prior SEC filing
07 Nov 2025
Source filing
View source filing
Reporting owner 1 detail
Reporting owner signature
By: Patrick R. O'Neil, attorney-in-fact For: Richard S. Geary

Key filing fact

Richard S. Geary filed Form 4 for IONIS PHARMACEUTICALS INC (IONS) on 07 Nov 2025.

Key facts

  • This page summarizes Richard S. Geary's Form 4 filing for IONIS PHARMACEUTICALS INC (IONS).
  • 12 reported transactions and 4 derivative rows are listed below.
  • Accepted by SEC: 07 Nov 2025, 17:12.

Change

  • Previous filing in this sequence was filed on 07 Nov 2025.
  • Current net transaction value: -$576,508.

Research use

  • This tells you what this filing adds before you inspect full transaction and derivative tables.
  • You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001442730 Primary reporting owner

Geary Richard S

Relationship
EVP, Chief Development Officer
Address
2855 GAZELLE COURT, CARLSBAD
Signature
By: Patrick R. O'Neil, attorney-in-fact For: Richard S. Geary
Signature date
07 Nov 2025

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

IONS transaction

Common Stock

Options Exercise

Transaction value
$45,424
Shares
+800
Change %
+1.3%
Price
$56.78
Shares after
60,457
Date
05 Nov 2025
Ownership
Direct
IONS transaction

Common Stock

Sale

Transaction value
$60,008
Shares
-800
Change %
-1.3%
Price
$75.01
Shares after
59,657
Date
05 Nov 2025
Ownership
Direct
Footnotes
F1, F2
IONS transaction

Common Stock

Options Exercise

Transaction value
$48,773
Shares
+801
Change %
+1.3%
Price
$60.89
Shares after
60,458
Date
05 Nov 2025
Ownership
Direct
IONS transaction

Common Stock

Sale

Transaction value
$60,083
Shares
-801
Change %
-1.3%
Price
$75.01
Shares after
59,657
Date
05 Nov 2025
Ownership
Direct
Footnotes
F1, F2
IONS transaction

Common Stock

Options Exercise

Transaction value
$836,824
Shares
+14,738
Change %
+25%
Price
$56.78
Shares after
74,395
Date
06 Nov 2025
Ownership
Direct
IONS transaction

Common Stock

Sale

Transaction value
$1,121,521
Shares
-14,738
Change %
-20%
Price
$76.10
Shares after
59,657
Date
06 Nov 2025
Ownership
Direct
Footnotes
F1, F3
IONS transaction

Common Stock

Options Exercise

Transaction value
$1,114,287
Shares
+18,300
Change %
+31%
Price
$60.89
Shares after
77,957
Date
06 Nov 2025
Ownership
Direct
IONS transaction

Common Stock

Sale

Transaction value
$1,380,204
Shares
-18,300
Change %
-23%
Price
$75.42
Shares after
59,657
Date
06 Nov 2025
Ownership
Direct
Footnotes
F1, F4

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

IONS transaction Derivative

Non-Qualified Stock Option (right to buy)

Options Exercise

Transaction value
$0
Shares
-800
Change %
-5.1%
Price
$0.000000
Shares after
14,738
Date
05 Nov 2025
Ownership
Direct
Underlying class
Common Stock
Underlying amount
800
Exercise price
$56.78
IONS transaction Derivative

Non-Qualified Stock Option (right to buy)

Options Exercise

Transaction value
$0
Shares
-14,738
Change %
-100%
Price
$0.000000
Shares after
0
Date
06 Nov 2025
Ownership
Direct
Underlying class
Common Stock
Underlying amount
14,738
Exercise price
$56.78
IONS transaction Derivative

Non-Qualified Stock Option (right to buy)

Options Exercise

Transaction value
$0
Shares
-801
Change %
-4.2%
Price
$0.000000
Shares after
18,300
Date
05 Nov 2025
Ownership
Direct
Underlying class
Common Stock
Underlying amount
801
Exercise price
$60.89
IONS transaction Derivative

Non-Qualified Stock Option (right to buy)

Options Exercise

Transaction value
$0
Shares
-18,300
Change %
-100%
Price
$0.000000
Shares after
0
Date
06 Nov 2025
Ownership
Direct
Underlying class
Common Stock
Underlying amount
18,300
Exercise price
$60.89
* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Rule 10b5-1 trading plan

These transactions were reported as open-market trades under a Rule 10b5-1 plan. The plan lets an insider set trading instructions in advance, which can reduce the risk of trading while in possession of material nonpublic information.

Original filing language: transaction made pursuant to a contract, instruction, or written plan intended to satisfy Rule 10b5-1(c).

Explanation of responses 4 footnotes

Footnote F1

Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on May 6, 2025.

Footnote F2

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $75.00 to $75.05 inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc. any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) on this Form 4.

Footnote F3

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $75.02 to $75.84 inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc. any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (3) on this Form 4.

Footnote F4

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $75.84 to $76.65 inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc. any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (4) on this Form 4.

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