Third Rock Ventures IV, L.P. - 23 Oct 2025 Form 4 Insider Report for Tango Therapeutics, Inc. (TNGX)

Reporting relationship: 10%+ Owner
Issuer ticker: TNGX
Reported as of: 23 Oct 2025
Net transaction value: -$4,846,575
SEC form: 4
Accepted by SEC: 27 Oct 2025, 16:15:03 UTC
Prior SEC filing: 29 Sep 2025
Next SEC filing: 05 Nov 2025
Source filing: View source filing
Reporting owner signature: /s/ Kevin Gillis, Chief Operating Officer of TRV GP IV, LLC, general partner of Third Rock Ventures GP IV, L.P., general partner of Third Rock Ventures IV, L.P.

Key filing fact

Third Rock Ventures IV, L.P. filed Form 4 for Tango Therapeutics, Inc. (TNGX) on 27 Oct 2025.

Key facts

This page summarizes Third Rock Ventures IV, L.P.'s Form 4 filing for Tango Therapeutics, Inc. (TNGX).
1 reported transaction and 0 derivative rows are listed below.
Accepted by SEC: 27 Oct 2025, 16:15.

Change

Previous filing in this sequence was filed on 29 Sep 2025.
Current net transaction value: -$4,846,575.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (3)

CIK 0001688327 Primary reporting owner

Third Rock Ventures IV, L.P.

Relationship: 10%+ Owner
Address: C/O THIRD ROCK VENTURES, LLC, 201 BROOKLINE AVE, SUITE 1401, BOSTON
Signature: /s/ Kevin Gillis, Chief Operating Officer of TRV GP IV, LLC, general partner of Third Rock Ventures GP IV, L.P., general partner of Third Rock Ventures IV, L.P.
Signature date: 27 Oct 2025

CIK 0001688326

Third Rock Ventures GP IV, L.P.

Relationship: 10%+ Owner
Address: 201 BROOKLINE AVE, SUITE 1401, BOSTON
Signature: /s/ Kevin Gillis, Chief Operating Officer of TRV GP IV, LLC, general partner of Third Rock Ventures GP IV, L.P.
Signature date: 27 Oct 2025

CIK 0001688325

TRV GP IV, LLC

Relationship: 10%+ Owner
Address: 201 BROOKLINE AVE, SUITE 1401, BOSTON
Signature: /s/ Kevin Gillis, Chief Operating Officer of TRV GP IV, LLC
Signature date: 27 Oct 2025

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

TNGX transaction

Common Stock

Sale

Transaction value: $4,846,575
Shares: -477,401
Change %: -3.4%
Price: $10.15
Shares after: 13,386,574
Date: 23 Oct 2025
Ownership: Direct
Footnotes: F1, F2

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 2 footnotes

Footnote F1

The price reported is a weighted average price. These shares were sold in multiple transactions at prices ranging from $10.00 to $10.65, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote (1).

Footnote F2

These shares are directly held by Third Rock Ventures IV, L.P. ("TRV IV"). The general partner of TRV IV is Third Rock Ventures GP IV, L.P. ("TRV GP IV"). The general partner of TRV GP IV is TRV GP IV, LLC ("TRV GP IV LLC"). Each of TRV GP IV and TRV GP IV LLC disclaims beneficial ownership of the shares except to the extent of its pecuniary interest therein, if any, and this report shall not be deemed an admission that it is the beneficial owner of such shares.