Michael Cloonan - 21 Oct 2025 Form 4 Insider Report for Sionna Therapeutics, Inc. (SION)

Source evidence Original filing metadata and source links for verification. 5 source fields
SEC form
4
Accepted by SEC
22 Oct 2025, 17:39:46 UTC
Prior SEC filing
17 Oct 2025
Next SEC filing
06 Jan 2026
Source filing
View source filing
Reporting owner 1 detail
Reporting owner signature
Jennifer Fitzpatrick, Attorney-in-Fact

Key filing fact

Michael Cloonan filed Form 4 for Sionna Therapeutics, Inc. (SION) on 22 Oct 2025.

Key facts

  • This page summarizes Michael Cloonan's Form 4 filing for Sionna Therapeutics, Inc. (SION).
  • 12 reported transactions and 4 derivative rows are listed below.
  • Accepted by SEC: 22 Oct 2025, 17:39.

Change

  • Previous filing in this sequence was filed on 17 Oct 2025.
  • Current net transaction value: -$3,008,782.

Research use

  • This tells you what this filing adds before you inspect full transaction and derivative tables.
  • You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001704336 Primary reporting owner

Cloonan Michael

Relationship
President & CEO, Director
Address
C/O SIONNA THERAPEUTICS, INC., 21 HICKORY DRIVE, SUITE 500, WALTHAM
Signature
Jennifer Fitzpatrick, Attorney-in-Fact
Signature date
22 Oct 2025

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

SION transaction

Common Stock

Options Exercise

Transaction value
$81,410
Shares
+13,324
Change %
+2.4%
Price
$6.11
Shares after
560,667
Date
21 Oct 2025
Ownership
Direct
Footnotes
F1
SION transaction

Common Stock

Sale

Transaction value
$458,879
Shares
-13,324
Change %
-2.4%
Price
$34.44
Shares after
547,343
Date
21 Oct 2025
Ownership
Direct
Footnotes
F1, F2
SION transaction

Common Stock

Options Exercise

Transaction value
$183,599
Shares
+30,049
Change %
+5.5%
Price
$6.11
Shares after
577,392
Date
21 Oct 2025
Ownership
Direct
Footnotes
F1
SION transaction

Common Stock

Sale

Transaction value
$1,070,646
Shares
-30,049
Change %
-5.2%
Price
$35.63
Shares after
547,343
Date
21 Oct 2025
Ownership
Direct
Footnotes
F1, F3
SION transaction

Common Stock

Options Exercise

Transaction value
$139,888
Shares
+22,895
Change %
+4.2%
Price
$6.11
Shares after
570,238
Date
21 Oct 2025
Ownership
Direct
Footnotes
F1
SION transaction

Common Stock

Sale

Transaction value
$837,957
Shares
-22,895
Change %
-4%
Price
$36.60
Shares after
547,343
Date
21 Oct 2025
Ownership
Direct
Footnotes
F1, F4
SION transaction

Common Stock

Options Exercise

Transaction value
$204,881
Shares
+33,532
Change %
+6.1%
Price
$6.11
Shares after
580,875
Date
21 Oct 2025
Ownership
Direct
Footnotes
F1
SION transaction

Common Stock

Sale

Transaction value
$1,251,079
Shares
-33,532
Change %
-5.8%
Price
$37.31
Shares after
547,343
Date
21 Oct 2025
Ownership
Direct
Footnotes
F1, F5

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

SION transaction Derivative

Non-Qualified Stock Option (right to buy)

Options Exercise

Transaction value
$0
Shares
-13,324
Change %
-8.7%
Price
$0.000000
Shares after
139,618
Date
21 Oct 2025
Ownership
Direct
Underlying class
Common Stock
Underlying amount
13,324
Exercise price
$6.11
Footnotes
F1, F6
SION transaction Derivative

Non-Qualified Stock Option (right to buy)

Options Exercise

Transaction value
$0
Shares
-30,049
Change %
-22%
Price
$0.000000
Shares after
109,569
Date
21 Oct 2025
Ownership
Direct
Underlying class
Common Stock
Underlying amount
30,049
Exercise price
$6.11
Footnotes
F1, F6
SION transaction Derivative

Non-Qualified Stock Option (right to buy)

Options Exercise

Transaction value
$0
Shares
-22,895
Change %
-21%
Price
$0.000000
Shares after
86,674
Date
21 Oct 2025
Ownership
Direct
Underlying class
Common Stock
Underlying amount
22,895
Exercise price
$6.11
Footnotes
F1, F6
SION transaction Derivative

Non-Qualified Stock Option (right to buy)

Options Exercise

Transaction value
$0
Shares
-33,532
Change %
-39%
Price
$0.000000
Shares after
53,142
Date
21 Oct 2025
Ownership
Direct
Underlying class
Common Stock
Underlying amount
33,532
Exercise price
$6.11
Footnotes
F1, F6
* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Rule 10b5-1 trading plan

These transactions were reported as open-market trades under a Rule 10b5-1 plan. The plan lets an insider set trading instructions in advance, which can reduce the risk of trading while in possession of material nonpublic information.

Original filing language: transaction made pursuant to a contract, instruction, or written plan intended to satisfy Rule 10b5-1(c).

Explanation of responses 6 footnotes

Footnote F1

This transaction was automatically executed pursuant to a Rule 10b5-1 trading plan adopted on May 21, 2025.

Footnote F2

The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $34.00 to $34.95, inclusive. The Reporting Person undertakes to provide to the Issuer, any securityholder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price at which the transactions were effected.

Footnote F3

The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $35.00 to $35.99, inclusive. The Reporting Person undertakes to provide to the Issuer, any securityholder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price at which the transactions were effected.

Footnote F4

The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $36.00 to $36.99, inclusive. The Reporting Person undertakes to provide to the Issuer, any securityholder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price at which the transactions were effected.

Footnote F5

The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $37.00 to $37.80, inclusive. The Reporting Person undertakes to provide to the Issuer, any securityholder of the Issuer or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price at which the transactions were effected.

Footnote F6

The shares underlying this option vest in forty-eight equal monthly installments following February 2, 2022, subject to the Reporting Person's continued service on each such vesting date.

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