Xiaodong Wang - 08 Sep 2026 Form 4 Insider Report for BeOne Medicines Ltd. (ONC)

Reporting relationship: Director, Chair, Scientific Advisory Brd
Issuer ticker: ONC
Reported as of: 08 Sep 2026
Net transaction value: -$13,366,092
SEC form: 4
Accepted by SEC: 10 Sep 2026, 16:49:55 UTC
Prior SEC filing: 15 Jun 2026
Source filing: View source filing
Reporting owner signature: /s/ Frank Collazo, as Attorney-in-Fact

Key filing fact

Xiaodong Wang filed Form 4 for BeOne Medicines Ltd. (ONC) on 10 Sep 2026.

Key facts

This page summarizes Xiaodong Wang's Form 4 filing for BeOne Medicines Ltd. (ONC).
10 reported transactions and 1 derivative row are listed below.
Accepted by SEC: 10 Sep 2026, 16:49.

Change

Previous filing in this sequence was filed on 15 Jun 2026.
Current net transaction value: -$13,366,092.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001662982 Primary reporting owner

Wang Xiaodong

Relationship: Director, Chair, Scientific Advisory Brd
Address: C/O BEONE MEDICINES I GMBH, AESCHENGRABEN 27, 21ST FLOOR, BASEL, SWITZERLAND
Signature: /s/ Frank Collazo, as Attorney-in-Fact
Signature date: 10 Sep 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

ONC transaction

American Depositary Shares

Sale

Transaction value: $407,897
Shares: -1,181
Change %: -16%
Price: $345.38
Shares after: 6,079
Date: 08 Sep 2026
Ownership: Direct
Footnotes: F4, F5, F6

ONC transaction

American Depositary Shares

Sale

Transaction value: $983,433
Shares: -2,841
Change %: -47%
Price: $346.16
Shares after: 3,238
Date: 08 Sep 2026
Ownership: Direct
Footnotes: F4, F5, F7

ONC transaction

American Depositary Shares

Sale

Transaction value: $526,993
Shares: -1,517
Change %: -47%
Price: $347.39
Shares after: 1,721
Date: 08 Sep 2026
Ownership: Direct
Footnotes: F4, F5, F8

ONC transaction

American Depositary Shares

Sale

Transaction value: $598,930
Shares: -1,721
Change %: -100%
Price: $348.01
Shares after: 0
Date: 08 Sep 2026
Ownership: Direct
Footnotes: F4, F5, F9

ONC transaction

American Depositary Shares

Options Exercise

Transaction value
Shares: +31,027
Change %
Price: $36.90^*
Shares after: 31,027
Date: 08 Sep 2026
Ownership: Direct
Footnotes: F4

ONC transaction

American Depositary Shares

Sale

Transaction value: $2,609,573
Shares: -7,492
Change %: -24%
Price: $348.31
Shares after: 23,535
Date: 08 Sep 2026
Ownership: Direct
Footnotes: F4, F5, F10

ONC transaction

American Depositary Shares

Sale

Transaction value: $3,733,141
Shares: -10,688
Change %: -45%
Price: $349.28
Shares after: 12,847
Date: 08 Sep 2026
Ownership: Direct
Footnotes: F4, F5, F11

ONC transaction

American Depositary Shares

Sale

Transaction value: $2,300,951
Shares: -6,569
Change %: -51%
Price: $350.27
Shares after: 6,278
Date: 08 Sep 2026
Ownership: Direct
Footnotes: F4, F5, F12

ONC transaction

American Depositary Shares

Sale

Transaction value: $2,205,174
Shares: -6,278
Change %: -100%
Price: $351.25
Shares after: 0
Date: 08 Sep 2026
Ownership: Direct
Footnotes: F4, F5, F13

ONC holding

Ordinary Shares

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 4,588,113
Date: 08 Sep 2026
Ownership: Direct

ONC holding

Ordinary Shares

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 1,025,063
Date: 08 Sep 2026
Ownership: See Footnote
Footnotes: F1

ONC holding

Ordinary Shares

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 3,953,100
Date: 08 Sep 2026
Ownership: See Footnote
Footnotes: F2

ONC holding

Ordinary Shares

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 50
Date: 08 Sep 2026
Ownership: See Footnote
Footnotes: F3

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

ONC transaction Derivative

Share Option (Right to Buy)

Options Exercise

Transaction value
Shares: -403,351
Change %: -25%
Price: $0.000000^*
Shares after: 1,210,079
Date: 08 Sep 2026
Ownership: Direct
Underlying class: Ordinary Shares
Underlying amount: 403,351
Exercise price: $2.84
Footnotes: F14, F15

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Rule 10b5-1 trading plan

These transactions were reported as open-market trades under a Rule 10b5-1 plan. The plan lets an insider set trading instructions in advance, which can reduce the risk of trading while in possession of material nonpublic information.

Original filing language: transaction made pursuant to a contract, instruction, or written plan intended to satisfy Rule 10b5-1(c).

Explanation of responses 15 footnotes

Footnote F1

These securities are held by a family trust, the beneficiaries of which are the Reporting Person's family members, for which the Reporting Person disclaims beneficial ownership.

Footnote F2

These securities are held by Wang Investment LLC, of which 99% of the limited liability company interests are owned by two grantor retained annuity trusts, of which the Reporting Person's wife is a trustee, for which the Reporting Person disclaims beneficial ownership.

Footnote F3

These securities are held by the spouse of the Reporting Person.

Footnote F4

Each American Depositary Share represents 13 Ordinary Shares.

Footnote F5

The sale was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on June 9, 2026.

Footnote F6

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $344.71 to $345.66, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Footnote F7

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $345.71 to $346.70, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Footnote F8

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $346.79 to $347.78, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Footnote F9

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $347.80 to $348.07, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Footnote F10

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $348.07 to $348.79, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Footnote F11

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $348.80 to $349.74, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Footnote F12

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $349.81 to $350.80, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Footnote F13

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $350.82 to $351.74, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Footnote F14

The number of securities underlying each option and the exercise price therefor are represented in ordinary shares.

Footnote F15

These securities vest over a four-year period as follows: 25% on July 13, 2017, and the remaining in 36 successive equal monthly installments, subject to continued service. All unvested shares subject to this option are subject to accelerated vesting upon certain termination events.

SEC remarks

Exhibit List - Exhibit 24.1 - Power of Attorney