Opaleye Management Inc. - 01 Sep 2026 Form 4 Insider Report for Sol-Gel Technologies Ltd. (SLGL)

Reporting relationship: 10%+ Owner
Issuer ticker: SLGL
Reported as of: 01 Sep 2026
Net transaction value: +$116,488
SEC form: 4
Accepted by SEC: 03 Sep 2026, 16:05:22 UTC
Prior SEC filing: 31 Aug 2026
Source filing: View source filing
Reporting owner signature: Opaleye Management, Inc., By: /s/ James Silverman, President

Key filing fact

Opaleye Management Inc. filed Form 4 for Sol-Gel Technologies Ltd. (SLGL) on 03 Sep 2026.

Key facts

This page summarizes Opaleye Management Inc.'s Form 4 filing for Sol-Gel Technologies Ltd. (SLGL).
2 reported transactions and 0 derivative rows are listed below.
Accepted by SEC: 03 Sep 2026, 16:05.

Change

Previous filing in this sequence was filed on 31 Aug 2026.
Current net transaction value: +$116,488.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001595855 Primary reporting owner

Opaleye Management Inc.

Relationship: 10%+ Owner
Address: ONE BOSTON PLACE, 26TH FLOOR, BOSTON
Signature: Opaleye Management, Inc., By: /s/ James Silverman, President
Signature date: 03 Sep 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

SLGL transaction

Ordinary Shares, par value NIS 1.00 per share

Purchase

Transaction value: $54,434
Shares: +783
Change %: +0.15%
Price: $69.52
Shares after: 526,000
Date: 01 Sep 2026
Ownership: By Opaleye, L.P.
Footnotes: F1, F4

SLGL transaction

Ordinary Shares, par value NIS 1.00 per share

Purchase

Transaction value: $62,054
Shares: +900
Change %: +0.17%
Price: $68.95
Shares after: 526,900
Date: 02 Sep 2026
Ownership: By Opaleye, L.P.
Footnotes: F1, F3, F4

SLGL holding

Ordinary Shares, par value NIS 1.00 per share

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 15,000
Date: 01 Sep 2026
Ownership: By Managed Account
Footnotes: F2, F4

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 4 footnotes

Footnote F1

Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Fund.

Footnote F2

Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye Management, Inc. may be deemed to beneficially own the securities owned directly by the Managed Account.

Footnote F3

The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $68.94-$68.95 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each separate price within the range.

Footnote F4

Opaleye Management, Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management, Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.