Emily M. Leproust - 25 Aug 2026 Form 4 Insider Report for Twist Bioscience Corp (TWST)

Reporting relationship
Chief Executive Officer, Director
Issuer ticker
TWST
Reported as of
25 Aug 2026
Net transaction value
-$6,317,760
Source evidence Original filing metadata and source links for verification. 4 source fields
SEC form
4
Accepted by SEC
27 Aug 2026, 16:05:10 UTC
Prior SEC filing
25 Aug 2026
Source filing
View source filing
Reporting owner 1 detail
Reporting owner signature
/s/ Kendra Fox, as Attorney-in-Fact for Emily M. Leproust

Key filing fact

Emily M. Leproust filed Form 4 for Twist Bioscience Corp (TWST) on 27 Aug 2026.

Key facts

  • This page summarizes Emily M. Leproust's Form 4 filing for Twist Bioscience Corp (TWST).
  • 5 reported transactions and 5 derivative rows are listed below.
  • Accepted by SEC: 27 Aug 2026, 16:05.

Change

  • Previous filing in this sequence was filed on 25 Aug 2026.
  • Current net transaction value: -$6,317,760.

Research use

  • This tells you what this filing adds before you inspect full transaction and derivative tables.
  • You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001753655 Primary reporting owner

Leproust Emily M.

Relationship
Chief Executive Officer, Director
Address
C/O TWIST BIOSCIENCE CORPORATION, 681 GATEWAY BLVD., SOUTH SAN FRANCISCO
Signature
/s/ Kendra Fox, as Attorney-in-Fact for Emily M. Leproust
Signature date
27 Aug 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

TWST transaction

Common Stock

Sale

Transaction value
$1,904,333
Shares
-12,648
Change %
-1.6%
Price
$150.56
Shares after
799,651
Date
25 Aug 2026
Ownership
Direct
Footnotes
F1, F2
TWST transaction

Common Stock

Sale

Transaction value
$1,851,980
Shares
-12,236
Change %
-1.5%
Price
$151.36
Shares after
787,415
Date
25 Aug 2026
Ownership
Direct
Footnotes
F1, F3
TWST transaction

Common Stock

Sale

Transaction value
$979,433
Shares
-6,412
Change %
-0.81%
Price
$152.75
Shares after
781,003
Date
25 Aug 2026
Ownership
Direct
Footnotes
F1, F4
TWST transaction

Common Stock

Sale

Transaction value
$1,413,204
Shares
-9,181
Change %
-1.2%
Price
$153.93
Shares after
771,822
Date
25 Aug 2026
Ownership
Direct
Footnotes
F1, F5
TWST transaction

Common Stock

Sale

Transaction value
$168,809
Shares
-1,093
Change %
-0.14%
Price
$154.45
Shares after
770,729
Date
25 Aug 2026
Ownership
Direct
Footnotes
F1, F6

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

TWST holding Derivative

Employee Stock Option (right to buy)

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
0
Date
25 Aug 2026
Ownership
Direct
Underlying class
Common Stock
Underlying amount
0
Exercise price
$5.95
Footnotes
F7
TWST holding Derivative

Employee Stock Option (right to buy)

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
75,439
Date
25 Aug 2026
Ownership
Direct
Underlying class
Common Stock
Underlying amount
0
Exercise price
$8.82
Footnotes
F8
TWST holding Derivative

Employee Stock Option (right to buy)

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
133,269
Date
25 Aug 2026
Ownership
Direct
Underlying class
Common Stock
Underlying amount
0
Exercise price
$26.66
Footnotes
F9
TWST holding Derivative

Employee Stock Option (right to buy)

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
131,290
Date
25 Aug 2026
Ownership
Direct
Underlying class
Common Stock
Underlying amount
0
Exercise price
$23.33
Footnotes
F10
TWST holding Derivative

Employee Stock Option (right to buy)

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
64,950
Date
25 Aug 2026
Ownership
Direct
Underlying class
Common Stock
Underlying amount
64,950
Exercise price
$67.85
Footnotes
F11
* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Rule 10b5-1 trading plan

These transactions were reported as open-market trades under a Rule 10b5-1 plan. The plan lets an insider set trading instructions in advance, which can reduce the risk of trading while in possession of material nonpublic information.

Original filing language: transaction made pursuant to a contract, instruction, or written plan intended to satisfy Rule 10b5-1(c).

Explanation of responses 11 footnotes

Footnote F1

The transactions reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person on May 27, 2025.

Footnote F2

Represents the weighted average sales price per share. The shares sold at prices ranging from $150.00 to $150.99 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.

Footnote F3

Represents the weighted average sales price per share. The shares sold at prices ranging from $151.00 to $151.97 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.

Footnote F4

Represents the weighted average sales price per share. The shares sold at prices ranging from $152.33 to $153.32 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.

Footnote F5

Represents the weighted average sales price per share. The shares sold at prices ranging from $153.34 to $154.33 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.

Footnote F6

Represents the weighted average sales price per share. The shares sold at prices ranging from $154.34 to $154.64 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.

Footnote F7

The option is immediately exercisable. 25% of the shares subject to the option vested on September 1, 2016 and 1/48th of the shares subject to the option vest on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.

Footnote F8

The option is immediately exercisable. 10% of the shares subject to the option vested on September 28, 2017, 15% of the shares subject to the option vested on September 28, 2018, and 1/48th of the shares subject to the option vest on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.

Footnote F9

20% of the shares subject to the option vested and became exercisable on October 31, 2019 and 1/60th of the shares subject to the option vest and become exercisable on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.

Footnote F10

25% of the shares subject to the option vested on October 24, 2020, and 1/48th of the shares subject to the option vest on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.

Footnote F11

Represents performance stock options granted to the reporting person on September 1, 2020, that vested and became exercisable on December 19, 2022 as a result of the reporting person having met the applicable performance criteria.

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