Emily M. Leproust - 12 Aug 2026 Form 4 Insider Report for Twist Bioscience Corp (TWST)

Reporting relationship: Chief Executive Officer, Director
Issuer ticker: TWST
Reported as of: 12 Aug 2026
Net transaction value: -$2,495,508
SEC form: 4
Accepted by SEC: 14 Aug 2026, 16:05:05 UTC
Prior SEC filing: 12 Aug 2026
Source filing: View source filing
Reporting owner signature: /s/ Kendra Fox, as Attorney-in-Fact for Emily M. Leproust

Key filing fact

Emily M. Leproust filed Form 4 for Twist Bioscience Corp (TWST) on 14 Aug 2026.

Key facts

This page summarizes Emily M. Leproust's Form 4 filing for Twist Bioscience Corp (TWST).
3 reported transactions and 5 derivative rows are listed below.
Accepted by SEC: 14 Aug 2026, 16:05.

Change

Previous filing in this sequence was filed on 12 Aug 2026.
Current net transaction value: -$2,495,508.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001753655 Primary reporting owner

Leproust Emily M.

Relationship: Chief Executive Officer, Director
Address: C/O TWIST BIOSCIENCE CORPORATION, 681 GATEWAY BLVD., SOUTH SAN FRANCISCO
Signature: /s/ Kendra Fox, as Attorney-in-Fact for Emily M. Leproust
Signature date: 14 Aug 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

TWST transaction

Common Stock

Options Exercise

Transaction value
Shares: +19,952
Change %: +2.4%
Price: $26.66^*
Shares after: 838,890
Date: 12 Aug 2026
Ownership: Direct
Footnotes: F1

TWST transaction

Common Stock

Sale

Transaction value: $2,495,508
Shares: -19,952
Change %: -2.4%
Price: $125.08
Shares after: 818,938
Date: 12 Aug 2026
Ownership: Direct
Footnotes: F1, F2

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

TWST transaction Derivative

Employee Stock Option (right to buy)

Options Exercise

Transaction value
Shares: -19,952
Change %: -13%
Price: $0.000000^*
Shares after: 133,269
Date: 12 Aug 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 19,952
Exercise price: $26.66
Footnotes: F7

TWST holding Derivative

Employee Stock Option (right to buy)

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 0
Date: 12 Aug 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 0
Exercise price: $5.95
Footnotes: F3

TWST holding Derivative

Employee Stock Option (right to buy)

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 131,290
Date: 12 Aug 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 0
Exercise price: $23.33
Footnotes: F4

TWST holding Derivative

Employee Stock Option (right to buy)

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 64,950
Date: 12 Aug 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 0
Exercise price: $67.85
Footnotes: F5

TWST holding Derivative

Employee Stock Option (right to buy)

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 75,439
Date: 12 Aug 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 0
Exercise price: $8.82
Footnotes: F6

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Rule 10b5-1 trading plan

These transactions were reported as open-market trades under a Rule 10b5-1 plan. The plan lets an insider set trading instructions in advance, which can reduce the risk of trading while in possession of material nonpublic information.

Original filing language: transaction made pursuant to a contract, instruction, or written plan intended to satisfy Rule 10b5-1(c).

Explanation of responses 7 footnotes

Footnote F1

The transactions reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person on May 27, 2025.

Footnote F2

Represents the weighted average sales price per share. The shares sold at prices ranging from $125.00 to $125.25 per share. Full information regarding the number of shares sold at each price shall be provided upon request to the staff of the U.S. Securities and Exchange Commission, the Issuer, or a security holder of the Issuer.

Footnote F3

The option is immediately exercisable. 25% of the shares subject to the option vested on September 1, 2016 and 1/48th of the shares subject to the option vest on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.

Footnote F4

25% of the shares subject to the option vested on October 24, 2020, and 1/48th of the shares subject to the option vest on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.

Footnote F5

Represents performance stock options granted to the reporting person on September 1, 2020, that vested and became exercisable on December 19, 2022 as a result of the reporting person having met the applicable performance criteria.

Footnote F6

The option is immediately exercisable. 10% of the shares subject to the option vested on September 28, 2017, 15% of the shares subject to the option vested on September 28, 2018, and 1/48th of the shares subject to the option vest on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.

Footnote F7

20% of the shares subject to the option vested and became exercisable on October 31, 2019 and 1/60th of the shares subject to the option vest and become exercisable on each monthly anniversary thereafter, subject to the Reporting Person's continuous service through each vesting date.