Adrian W. Quartel - 27 Jul 2026 Form 4 Insider Report for SPRUCE BIOSCIENCES, INC. (SPRB)

Reporting relationship: Chief Medical Officer
Issuer ticker: SPRB
Reported as of: 27 Jul 2026
Net transaction value: $0
SEC form: 4
Accepted by SEC: 29 Jul 2026, 16:10:50 UTC
Prior SEC filing: 02 Feb 2026
Source filing: View source filing
Reporting owner signature: /s/ Samir Gharib, Attorney-in-Fact

Key filing fact

Adrian W. Quartel filed Form 4 for SPRUCE BIOSCIENCES, INC. (SPRB) on 29 Jul 2026.

Key facts

This page summarizes Adrian W. Quartel's Form 4 filing for SPRUCE BIOSCIENCES, INC. (SPRB).
1 reported transaction and 1 derivative row are listed below.
Accepted by SEC: 29 Jul 2026, 16:10.

Change

Previous filing in this sequence was filed on 02 Feb 2026.
Current net transaction value: $0.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001910132 Primary reporting owner

Quartel Adrian W

Relationship: Chief Medical Officer
Address: C/O SPRUCE BIOSCIENCES, INC., 611 GATEWAY BOULEVARD, SUITE 740, SOUTH SAN FRANCISCO
Signature: /s/ Samir Gharib, Attorney-in-Fact
Signature date: 29 Jul 2026

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

SPRB transaction Derivative

Restricted Stock Units

Award

Transaction value
Shares: +13,000
Change %
Price: $0.000000^*
Shares after: 13,000
Date: 27 Jul 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 13,000
Exercise price: $0.000000
Footnotes: F1, F2

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 2 footnotes

Footnote F1

Each Restricted Stock Unit ("RSU") represents a contingent right to receive one share of the Issuer's common stock.

Footnote F2

25% of the total number of restricted stock units ("RSUs") will vest on June 15, 2027. 25% of the total number of RSUs will vest on each of June 15, 2028, June 15, 2029 and June 15, 2030, subject to the Reporting Person's Continuous Service (as defined in the Issuer's 2020 Equity Incentive Plan) as of each such vesting date.