William John Sibold - 17 Jul 2026 Form 4 Insider Report for MADRIGAL PHARMACEUTICALS, INC. (MDGL)

Reporting relationship: President and CEO, Director
Issuer ticker: MDGL
Reported as of: 17 Jul 2026
Net transaction value: -$1,368,253
SEC form: 4
Accepted by SEC: 20 Jul 2026, 21:16:52 UTC
Prior SEC filing: 06 Mar 2026
Source filing: View source filing
Reporting owner signature: /s/ Mardi Dier, as Attorney-in-Fact

Key filing fact

William John Sibold filed Form 4 for MADRIGAL PHARMACEUTICALS, INC. (MDGL) on 20 Jul 2026.

Key facts

This page summarizes William John Sibold's Form 4 filing for MADRIGAL PHARMACEUTICALS, INC. (MDGL).
12 reported transactions and 1 derivative row are listed below.
Accepted by SEC: 20 Jul 2026, 21:16.

Change

Previous filing in this sequence was filed on 06 Mar 2026.
Current net transaction value: -$1,368,253.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001518611 Primary reporting owner

Sibold William John

Relationship: President and CEO, Director
Address: C/O MADRIGAL PHARMACEUTICALS, INC., 1001 CONSHOHOCKEN STATE ROAD SUITE 2-350, WEST CONSHOHOCKEN
Signature: /s/ Mardi Dier, as Attorney-in-Fact
Signature date: 20 Jul 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

MDGL transaction

Common Stock

Options Exercise

Transaction value
Shares: +50,000
Change %: +31%
Price
Shares after: 211,829
Date: 17 Jul 2026
Ownership: Direct
Footnotes: F1

MDGL transaction

Common Stock

Sale

Transaction value: $75,984
Shares: -140
Change %: -0.07%
Price: $542.75
Shares after: 211,689
Date: 20 Jul 2026
Ownership: Direct
Footnotes: F2, F3

MDGL transaction

Common Stock

Sale

Transaction value: $59,817
Shares: -110
Change %: -0.05%
Price: $543.79
Shares after: 211,579
Date: 20 Jul 2026
Ownership: Direct
Footnotes: F2, F4

MDGL transaction

Common Stock

Sale

Transaction value: $296,869
Shares: -545
Change %: -0.26%
Price: $544.71
Shares after: 211,034
Date: 20 Jul 2026
Ownership: Direct
Footnotes: F2, F5

MDGL transaction

Common Stock

Sale

Transaction value: $150,070
Shares: -275
Change %: -0.13%
Price: $545.71
Shares after: 210,759
Date: 20 Jul 2026
Ownership: Direct
Footnotes: F2, F6

MDGL transaction

Common Stock

Sale

Transaction value: $147,164
Shares: -269
Change %: -0.13%
Price: $547.08
Shares after: 210,490
Date: 20 Jul 2026
Ownership: Direct
Footnotes: F2, F7

MDGL transaction

Common Stock

Sale

Transaction value: $372,435
Shares: -680
Change %: -0.32%
Price: $547.70
Shares after: 209,810
Date: 20 Jul 2026
Ownership: Direct
Footnotes: F2, F8

MDGL transaction

Common Stock

Sale

Transaction value: $25,797
Shares: -47
Change %: -0.02%
Price: $548.87
Shares after: 209,763
Date: 20 Jul 2026
Ownership: Direct
Footnotes: F2, F9

MDGL transaction

Common Stock

Sale

Transaction value: $84,152
Shares: -153
Change %: -0.07%
Price: $550.01
Shares after: 209,610
Date: 20 Jul 2026
Ownership: Direct
Footnotes: F2, F10

MDGL transaction

Common Stock

Sale

Transaction value: $551
Shares: -1
Change %: -0%
Price: $550.72
Shares after: 209,609
Date: 20 Jul 2026
Ownership: Direct
Footnotes: F2

MDGL transaction

Common Stock

Sale

Transaction value: $155,414
Shares: -280
Change %: -0.13%
Price: $555.05
Shares after: 209,329
Date: 20 Jul 2026
Ownership: Direct
Footnotes: F2, F11

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

MDGL transaction Derivative

Performance Restricted Stock Units

Options Exercise

Transaction value
Shares: -50,000
Change %: -100%
Price: $0.000000^*
Shares after: 0
Date: 17 Jul 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 50,000
Exercise price
Footnotes: F12

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 12 footnotes

Footnote F1

On July 17, 2026, the Reporting Person earned 50,000 shares of common stock following the achievement of the performance and service conditions of the Performance Restricted Stock Units described in Footnote 12. Pursuant to the terms of the award, certain of these shares were sold to cover certain tax withholding obligations as described in Footnote 2 below. The Issuer is irrevocably obligated to issue the remaining shares to the Reporting Person on September 8, 2029, the sixth anniversary of the commencement of his employment with the Issuer.

Footnote F2

The sale reported on this line represents the number of shares sold by the Issuer on behalf of the Reporting Person to cover certain tax withholding obligations in connection with the Reporting Person earning 50,000 shares of common stock as described in Footnote 1 above. This sale was automatic and not at the discretion of the Reporting Person.

Footnote F3

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $542.22 to $543.16, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote and the footnotes below.

Footnote F4

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $543.26 to $544.25, inclusive.

Footnote F5

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $544.31 to $545.28, inclusive.

Footnote F6

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $545.31 to $546.29, inclusive.

Footnote F7

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $546.37 to $547.35, inclusive.

Footnote F8

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $547.40 to $548.29, inclusive.

Footnote F9

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $548.42 to $549.39, inclusive.

Footnote F10

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $549.70 to $550.24, inclusive.

Footnote F11

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $555.00 to $555.10, inclusive.

Footnote F12

On September 11, 2023, the Reporting Person was granted a one-time sign-on award of Performance Restricted Stock Units with a target award of 50,000 shares of common stock that could be earned upon the achievement of significant sustained stock price appreciation hurdles over a five-year period. The Reporting Person was eligible to earn up to 300% of the target award. Following the achievement of the first hurdle in February 2025, the second hurdle in December 2025 and the third and final hurdle reported on this line, all performance hurdles have been achieved. See the Issuer's Schedule 14A filed with the Securities and Exchange Commission on April 29, 2024 for additional information about the Performance Restricted Stock Units.