| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Sibold William John | President and CEO, Director | C/O MADRIGAL PHARMACEUTICALS, INC., 200 BARR HARBOR DRIVE, SUITE 200, WEST CONSHOHOCKEN | /s/ Mardi Dier, as Attorney-in-Fact | 06 Mar 2026 | 0001518611 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | MDGL | Common Stock | Award | +14,995 | +10% | $0.000000* | 163,492 | 04 Mar 2026 | Direct | F1 | |
| transaction | MDGL | Common Stock | Sale | $718,316 | -1,663 | -1% | $431.94 | 161,829 | 06 Mar 2026 | Direct | F2 |
| Type | Sym | Class | Transaction | Value $ | Shares | Change % | * Price $ | Shares After | Date | Underlying Class | Amount | Exercise Price | Ownership | Footnotes |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| transaction | MDGL | Stock Option (Right to Buy) | Award | +18,743 | $0.000000* | 18,743 | 04 Mar 2026 | Common Stock | 18,743 | $434.80 | Direct | F3 |
| Id | Content |
|---|---|
| F1 | Represents a grant of restricted stock units, which vest as to 25% of the shares on each of March 4, 2027, March 4, 2028, March 4, 2029 and March 4, 2030, provided the Reporting Person continues in service with the Issuer on each such date. |
| F2 | This sale represents the number of shares sold by the Issuer on behalf of the Reporting Person to cover tax withholding obligations in connection with the vesting of restricted stock units. This sale was automatic and not at the discretion of the Reporting Person. |
| F3 | The option vests as to 25% of the shares on the first anniversary of the date of grant (March 4, 2027) and, thereafter, 6.25% of the shares shall vest on the last day of each successive three-month period, provided the Reporting Person continues in service with the Issuer on each such date. |