Holly B. Kordasiewicz - 12 Jun 2026 Form 4 Insider Report for IONIS PHARMACEUTICALS INC (IONS)

Source evidence Original filing metadata and source links for verification. 4 source fields
SEC form
4
Accepted by SEC
16 Jun 2026, 17:26:18 UTC
Prior SEC filing
20 Jan 2026
Source filing
View source filing
Reporting owner 1 detail
Reporting owner signature
By: Patrick R. O'Neil, attorney-in-fact For: Holly Kordasiewicz

Key filing fact

Holly B. Kordasiewicz filed Form 4 for IONIS PHARMACEUTICALS INC (IONS) on 16 Jun 2026.

Key facts

  • This page summarizes Holly B. Kordasiewicz's Form 4 filing for IONIS PHARMACEUTICALS INC (IONS).
  • 10 reported transactions and 4 derivative rows are listed below.
  • Accepted by SEC: 16 Jun 2026, 17:26.

Change

  • Previous filing in this sequence was filed on 20 Jan 2026.
  • Current net transaction value: -$4,466,428.

Research use

  • This tells you what this filing adds before you inspect full transaction and derivative tables.
  • You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0002102721 Primary reporting owner

Kordasiewicz Holly B.

Relationship
EVP, Chief Development Officer
Address
2855 GAZELLE COURT, CARLSBAD
Signature
By: Patrick R. O'Neil, attorney-in-fact For: Holly Kordasiewicz
Signature date
16 Jun 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

IONS transaction

Common Stock

Options Exercise

Transaction value
Shares
+7,951
Change %
+35%
Price
$60.89*
Shares after
30,409
Date
12 Jun 2026
Ownership
Direct
IONS transaction

Common Stock

Options Exercise

Transaction value
Shares
+21,000
Change %
+69%
Price
$60.89*
Shares after
51,409
Date
12 Jun 2026
Ownership
Direct
IONS transaction

Common Stock

Options Exercise

Transaction value
Shares
+12,000
Change %
+23%
Price
$32.60*
Shares after
63,409
Date
12 Jun 2026
Ownership
Direct
IONS transaction

Common Stock

Options Exercise

Transaction value
Shares
+19,895
Change %
+31%
Price
$56.78*
Shares after
83,304
Date
12 Jun 2026
Ownership
Direct
IONS transaction

Common Stock

Sale

Transaction value
$2,997,122
Shares
-41,004
Change %
-49%
Price
$73.09
Shares after
42,300
Date
12 Jun 2026
Ownership
Direct
Footnotes
F1, F2
IONS transaction

Common Stock

Sale

Transaction value
$1,469,306
Shares
-19,842
Change %
-47%
Price
$74.05
Shares after
22,458
Date
12 Jun 2026
Ownership
Direct
Footnotes
F1, F3

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

IONS transaction Derivative

Non-Qualified Stock Option (right to buy)

Options Exercise

Transaction value
Shares
-12,000
Change %
-100%
Price
$0.000000*
Shares after
0
Date
12 Jun 2026
Ownership
Direct
Underlying class
Common Stock
Underlying amount
12,000
Exercise price
$32.60
IONS transaction Derivative

Non-Qualified Stock Option (right to buy)

Options Exercise

Transaction value
Shares
-19,895
Change %
-100%
Price
$0.000000*
Shares after
0
Date
12 Jun 2026
Ownership
Direct
Underlying class
Common Stock
Underlying amount
19,895
Exercise price
$56.78
IONS transaction Derivative

Non-Qualified Stock Option (right to buy)

Options Exercise

Transaction value
Shares
-7,951
Change %
-27%
Price
$0.000000*
Shares after
21,000
Date
12 Jun 2026
Ownership
Direct
Underlying class
Common Stock
Underlying amount
7,951
Exercise price
$60.89
IONS transaction Derivative

Non-Qualified Stock Option (right to buy)

Options Exercise

Transaction value
Shares
-21,000
Change %
-100%
Price
$0.000000*
Shares after
0
Date
12 Jun 2026
Ownership
Direct
Underlying class
Common Stock
Underlying amount
21,000
Exercise price
$60.89
* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Rule 10b5-1 trading plan

These transactions were reported as open-market trades under a Rule 10b5-1 plan. The plan lets an insider set trading instructions in advance, which can reduce the risk of trading while in possession of material nonpublic information.

Original filing language: transaction made pursuant to a contract, instruction, or written plan intended to satisfy Rule 10b5-1(c).

Explanation of responses 3 footnotes

Footnote F1

Shares sold pursuant to a Rule 10b5-1 Trading Plan adopted by the reporting person on March 13, 2026

Footnote F2

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $72.68 to $73.67 inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc. any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (2) on this Form 4.

Footnote F3

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $73.735 to $74.28 inclusive. The reporting person undertakes to provide to Ionis Pharmaceuticals, Inc. any security holder of Ionis Pharmaceuticals, Inc. or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (3) on this Form 4.

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