John Oyler - 11 Jun 2026 Form 4 Insider Report for BeOne Medicines Ltd. (ONC)

Reporting relationship: Chief Executive Officer, Director
Issuer ticker: ONC
Reported as of: 11 Jun 2026
Net transaction value: -$501,355
SEC form: 4
Accepted by SEC: 15 Jun 2026, 17:55:00 UTC
Prior SEC filing: 10 Jun 2026
Next SEC filing: 18 Jun 2026
Source filing: View source filing
Reporting owner signature: /s/ Qing Nian, as Attorney-in-Fact

Key filing fact

John Oyler filed Form 4 for BeOne Medicines Ltd. (ONC) on 15 Jun 2026.

Key facts

This page summarizes John Oyler's Form 4 filing for BeOne Medicines Ltd. (ONC).
6 reported transactions and 1 derivative row are listed below.
Accepted by SEC: 15 Jun 2026, 17:55.

Change

Previous filing in this sequence was filed on 10 Jun 2026.
Current net transaction value: -$501,355.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001042047 Primary reporting owner

OYLER JOHN

Relationship: Chief Executive Officer, Director
Address: C/O BEONE MEDICINES I GMBH, AESCHENGRABEN 27, 21ST FLOOR, BASEL, SWITZERLAND
Signature: /s/ Qing Nian, as Attorney-in-Fact
Signature date: 15 Jun 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

ONC transaction

Ordinary Shares

Award

Transaction value
Shares: +177,931
Change %: +3.2%
Price: $0.000000^*
Shares after: 5,697,649
Date: 11 Jun 2026
Ownership: Direct
Footnotes: F1

ONC transaction

American Depositary Shares

Sale

Transaction value: $189,865
Shares: -741
Change %: -38%
Price: $256.23
Shares after: 1,208
Date: 11 Jun 2026
Ownership: Direct
Footnotes: F7, F8, F9

ONC transaction

American Depositary Shares

Sale

Transaction value: $221,271
Shares: -859
Change %: -71%
Price: $257.59
Shares after: 349
Date: 11 Jun 2026
Ownership: Direct
Footnotes: F7, F8, F10

ONC transaction

American Depositary Shares

Sale

Transaction value: $51,656
Shares: -200
Change %: -57%
Price: $258.28
Shares after: 149
Date: 11 Jun 2026
Ownership: Direct
Footnotes: F7, F8, F11

ONC transaction

American Depositary Shares

Sale

Transaction value: $38,563
Shares: -149
Change %: -100%
Price: $258.81
Shares after: 0
Date: 11 Jun 2026
Ownership: Direct
Footnotes: F7, F8

ONC holding

Ordinary Shares

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 481,533
Date: 11 Jun 2026
Ownership: See Footnote
Footnotes: F2

ONC holding

Ordinary Shares

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 7,699,158
Date: 11 Jun 2026
Ownership: See Footnote
Footnotes: F3

ONC holding

Ordinary Shares

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 28,204,115
Date: 11 Jun 2026
Ownership: See Footnote
Footnotes: F4

ONC holding

Ordinary Shares

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 9,545,000
Date: 11 Jun 2026
Ownership: See Footnote
Footnotes: F5

ONC holding

Ordinary Shares

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after: 102,188
Date: 11 Jun 2026
Ownership: See Footnote
Footnotes: F6

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

ONC transaction Derivative

Share Option (Right to Buy)

Award

Transaction value
Shares: +344,669
Change %
Price: $0.000000^*
Shares after: 344,669
Date: 11 Jun 2026
Ownership: Direct
Underlying class: Ordinary Shares
Underlying amount: 344,669
Exercise price: $20.81
Footnotes: F12, F13

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 13 footnotes

Footnote F1

Represents securities underlying restricted share units. 1/4th of the securities will vest on each anniversary of June 11, 2026, subject to continued service. Unvested securities are subject to accelerated vesting upon a change of control or certain termination events.

Footnote F2

These securities are held by the P&O Trust, the beneficiaries of which include the Reporting Person's child and others, for which the Reporting Person disclaims beneficial ownership.

Footnote F3

These securities are held in a grantor retained annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership.

Footnote F4

These securities are held by Oyler Investment LLC, of which 99% of the the limited liability company interest owned by a grantor retain annuity trust, of which the Reporting Person's father is a trustee, for which the Reporting Person disclaims beneficial ownership.

Footnote F5

These securities are held for the benefit of the Reporting Person in a Roth IRA PENSCO trust account.

Footnote F6

These securities are held by The John Oyler Legacy Trust for the benefit of the Reporting Person's minor child, for which the Reporting Person disclaims beneficial ownership.

Footnote F7

Each American Depositary Share represents 13 Ordinary Shares

Footnote F8

The sale was effected pursuant to a mandatory tax withholding provision in the Reporting Person's restricted share unit award agreement in connection with the vesting of a restricted share unit award previously granted to the Reporting Person. 1/4th of the securities will vest on each anniversary of June 10, 2025, subject to continued service. Unvested securities are subject to accelerated vesting upon change of control or certain termination events.

Footnote F9

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $256.04 to $257.00, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Footnote F10

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $257.105 to $257.78, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Footnote F11

The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $258.1269 to $258.3723, inclusive. The Reporting Person has provided to the Issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the Issuer, upon request, full information regarding the number of American Depositary Shares sold at each separate price.

Footnote F12

The number of securities underlying each option and the exercise price therefor are represented in ordinary shares.

Footnote F13

These securities vest over a four-year period as follows: 25% on the first anniversary of June 11, 2026 with the remaining shares vesting in 36 equal successive monthly installments thereafter, subject to continued service. Unvested securities are subject to accelerated vesting upon a change of control or certain termination events.

We use cookies and similar technologies to provide certain features, enhance the user experience and, if you allow them, measure engagement and deliver advertising. Analytics and marketing storage stay off until you grant consent. By clicking on "Agree and continue", you declare your consent to the use of the selected optional cookies. to update or revoke optional consent for future visits. For more information, see our Privacy Policy .