BAKER BROS. ADVISORS LP - 08 Jun 2026 Form 4 Insider Report for INCYTE CORP (INCY)

Source evidence Original filing metadata and source links for verification. 5 source fields
SEC form
4
Accepted by SEC
10 Jun 2026, 16:41:15 UTC
Prior SEC filing
05 Jun 2026
Next SEC filing
10 Jun 2026
Source filing
View source filing
Reporting owner 1 detail
Reporting owner signature
By: Baker Bros. Advisors LP, Name: Scott L. Lessing, Title: President /s/ Scott L. Lessing

Key filing fact

BAKER BROS. ADVISORS LP filed Form 4 for INCYTE CORP (INCY) on 10 Jun 2026.

Key facts

  • This page summarizes BAKER BROS. ADVISORS LP's Form 4 filing for INCYTE CORP (INCY).
  • 4 reported transactions and 12 derivative rows are listed below.
  • Accepted by SEC: 10 Jun 2026, 16:41.

Change

  • Previous filing in this sequence was filed on 05 Jun 2026.
  • Current net transaction value: $0.

Research use

  • This tells you what this filing adds before you inspect full transaction and derivative tables.
  • You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (6)

CIK 0001263508 Primary reporting owner

BAKER BROS. ADVISORS LP

Relationship
Director, 10%+ Owner
Address
860 WASHINGTON STREET, 3RD FLOOR, NEW YORK
Signature
By: Baker Bros. Advisors LP, Name: Scott L. Lessing, Title: President /s/ Scott L. Lessing
Signature date
10 Jun 2026
CIK 0001551139

667, L.P.

Relationship
Director, 10%+ Owner
Address
860 WASHINGTON STREET, 3RD FLOOR, NEW YORK
Signature
Baker Bros. Advisors LP, Mgmt. Co. and Inv. Adviser to 667, L.P., pursuant to authority granted by Baker Biotech Capital, L.P., GP to 667, L.P. Name: Scott L. Lessing, Title: President /s/ Scott L. Lessing
Signature date
10 Jun 2026
CIK 0001580575

Baker Bros. Advisors (GP) LLC

Relationship
Director, 10%+ Owner
Address
860 WASHINGTON STREET, 3RD FLOOR, NEW YORK
Signature
/s/ Julian C. Baker
Signature date
10 Jun 2026
CIK 0001363364

Baker Brothers Life Sciences LP

Relationship
Director, 10%+ Owner
Address
860 WASHINGTON STREET, 3RD FLOOR, NEW YORK
Signature
By: Baker Bros. Advisors (GP) LLC, Name: Scott L. Lessing, Title: President /s/ Scott L. Lessing
Signature date
10 Jun 2026
CIK 0001087940

BAKER FELIX

Relationship
Director, 10%+ Owner
Address
860 WASHINGTON STREET, 3RD FLOOR, NEW YORK
Signature
Baker Bros. Advisors LP, Mgmt. Co. and Inv. Adviser to BAKER BROTHERS LIFE SCIENCES, L.P.,pursuant to authority granted by Baker Brothers Life Sciences Capital, L.P., GP to Baker Brothers Life Sciences, L.P., /s/ Name: Scott L. Lessing, Title: President
Signature date
10 Jun 2026
CIK 0001087939

BAKER JULIAN

Relationship
Director, 10%+ Owner
Address
860 WASHINGTON STREET, 3RD FLOOR, NEW YORK
Signature
/s/ Felix J. Baker
Signature date
10 Jun 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

INCY transaction

Common Stock

Award

Transaction value
Shares
+1,642
Change %
+0.06%
Price
$0.000000*
Shares after
2,834,681
Date
08 Jun 2026
Ownership
See Footnotes
Footnotes
F1, F2, F3, F4, F5, F6, F7, F8
INCY transaction

Common Stock

Award

Transaction value
Shares
+1,642
Change %
+0.06%
Price
$0.000000*
Shares after
2,834,681
Date
08 Jun 2026
Ownership
See Footnotes
Footnotes
F1, F2, F3, F4, F5, F6, F7, F8
INCY transaction

Common Stock

Award

Transaction value
Shares
+1,642
Change %
+0.06%
Price
$0.000000*
Shares after
2,834,681
Date
08 Jun 2026
Ownership
See Footnotes
Footnotes
F1, F2, F3, F4, F5, F6, F7, F8
INCY transaction

Common Stock

Award

Transaction value
Shares
+1,642
Change %
+0.06%
Price
$0.000000*
Shares after
2,834,681
Date
08 Jun 2026
Ownership
See Footnotes
Footnotes
F1, F2, F3, F4, F5, F6, F7, F8
INCY transaction

Common Stock

Award

Transaction value
Shares
+1,642
Change %
+0.06%
Price
$0.000000*
Shares after
2,834,681
Date
08 Jun 2026
Ownership
See Footnotes
Footnotes
F1, F2, F3, F4, F5, F6, F7, F8
INCY transaction

Common Stock

Award

Transaction value
Shares
+1,642
Change %
+0.06%
Price
$0.000000*
Shares after
2,834,681
Date
08 Jun 2026
Ownership
See Footnotes
Footnotes
F1, F2, F3, F4, F5, F6, F7, F8
INCY transaction

Common Stock

Award

Transaction value
Shares
+1,642
Change %
+0.01%
Price
$0.000000*
Shares after
28,205,360
Date
08 Jun 2026
Ownership
See Footnotes
Footnotes
F1, F3, F4, F5, F6, F7, F8, F9
INCY transaction

Common Stock

Award

Transaction value
Shares
+1,642
Change %
+0.01%
Price
$0.000000*
Shares after
28,205,360
Date
08 Jun 2026
Ownership
See Footnotes
Footnotes
F1, F3, F4, F5, F6, F7, F8, F9
INCY transaction

Common Stock

Award

Transaction value
Shares
+1,642
Change %
+0.01%
Price
$0.000000*
Shares after
28,205,360
Date
08 Jun 2026
Ownership
See Footnotes
Footnotes
F1, F3, F4, F5, F6, F7, F8, F9
INCY transaction

Common Stock

Award

Transaction value
Shares
+1,642
Change %
+0.01%
Price
$0.000000*
Shares after
28,205,360
Date
08 Jun 2026
Ownership
See Footnotes
Footnotes
F1, F3, F4, F5, F6, F7, F8, F9
INCY transaction

Common Stock

Award

Transaction value
Shares
+1,642
Change %
+0.01%
Price
$0.000000*
Shares after
28,205,360
Date
08 Jun 2026
Ownership
See Footnotes
Footnotes
F1, F3, F4, F5, F6, F7, F8, F9
INCY transaction

Common Stock

Award

Transaction value
Shares
+1,642
Change %
+0.01%
Price
$0.000000*
Shares after
28,205,360
Date
08 Jun 2026
Ownership
See Footnotes
Footnotes
F1, F3, F4, F5, F6, F7, F8, F9
INCY holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
278,773
Date
08 Jun 2026
Ownership
Direct
Footnotes
F10
INCY holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
278,773
Date
08 Jun 2026
Ownership
Direct
Footnotes
F10
INCY holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
278,773
Date
08 Jun 2026
Ownership
Direct
Footnotes
F10
INCY holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
278,773
Date
08 Jun 2026
Ownership
Direct
Footnotes
F10
INCY holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
278,773
Date
08 Jun 2026
Ownership
Direct
Footnotes
F10
INCY holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
278,773
Date
08 Jun 2026
Ownership
Direct
Footnotes
F10
INCY holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
281,190
Date
08 Jun 2026
Ownership
Direct
Footnotes
F11
INCY holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
281,190
Date
08 Jun 2026
Ownership
Direct
Footnotes
F11
INCY holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
281,190
Date
08 Jun 2026
Ownership
Direct
Footnotes
F11
INCY holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
281,190
Date
08 Jun 2026
Ownership
Direct
Footnotes
F11
INCY holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
281,190
Date
08 Jun 2026
Ownership
Direct
Footnotes
F11
INCY holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
281,190
Date
08 Jun 2026
Ownership
Direct
Footnotes
F11
INCY holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
33,410
Date
08 Jun 2026
Ownership
See Footnotes
Footnotes
F12
INCY holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
33,410
Date
08 Jun 2026
Ownership
See Footnotes
Footnotes
F12
INCY holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
33,410
Date
08 Jun 2026
Ownership
See Footnotes
Footnotes
F12
INCY holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
33,410
Date
08 Jun 2026
Ownership
See Footnotes
Footnotes
F12
INCY holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
33,410
Date
08 Jun 2026
Ownership
See Footnotes
Footnotes
F12
INCY holding

Common Stock

No transaction description listed

Transaction value
Shares
Change %
Price
Shares after
33,410
Date
08 Jun 2026
Ownership
See Footnotes
Footnotes
F12

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

INCY transaction Derivative

Non-Qualified Stock Options (right to buy)

Award

Transaction value
Shares
+6,111
Change %
Price
$0.000000*
Shares after
6,111
Date
08 Jun 2026
Ownership
See Footnotes
Underlying class
Common Stock
Underlying amount
6,111
Exercise price
$100.64
Footnotes
F2, F3, F4, F6, F7, F8, F13
INCY transaction Derivative

Non-Qualified Stock Options (right to buy)

Award

Transaction value
Shares
+6,111
Change %
Price
$0.000000*
Shares after
6,111
Date
08 Jun 2026
Ownership
See Footnotes
Underlying class
Common Stock
Underlying amount
6,111
Exercise price
$100.64
Footnotes
F2, F3, F4, F6, F7, F8, F13
INCY transaction Derivative

Non-Qualified Stock Options (right to buy)

Award

Transaction value
Shares
+6,111
Change %
Price
$0.000000*
Shares after
6,111
Date
08 Jun 2026
Ownership
See Footnotes
Underlying class
Common Stock
Underlying amount
6,111
Exercise price
$100.64
Footnotes
F2, F3, F4, F6, F7, F8, F13
INCY transaction Derivative

Non-Qualified Stock Options (right to buy)

Award

Transaction value
Shares
+6,111
Change %
Price
$0.000000*
Shares after
6,111
Date
08 Jun 2026
Ownership
See Footnotes
Underlying class
Common Stock
Underlying amount
6,111
Exercise price
$100.64
Footnotes
F2, F3, F4, F6, F7, F8, F13
INCY transaction Derivative

Non-Qualified Stock Options (right to buy)

Award

Transaction value
Shares
+6,111
Change %
Price
$0.000000*
Shares after
6,111
Date
08 Jun 2026
Ownership
See Footnotes
Underlying class
Common Stock
Underlying amount
6,111
Exercise price
$100.64
Footnotes
F2, F3, F4, F6, F7, F8, F13
INCY transaction Derivative

Non-Qualified Stock Options (right to buy)

Award

Transaction value
Shares
+6,111
Change %
Price
$0.000000*
Shares after
6,111
Date
08 Jun 2026
Ownership
See Footnotes
Underlying class
Common Stock
Underlying amount
6,111
Exercise price
$100.64
Footnotes
F2, F3, F4, F6, F7, F8, F13
INCY transaction Derivative

Non-Qualified Stock Options (right to buy)

Award

Transaction value
Shares
+6,111
Change %
Price
$0.000000*
Shares after
6,111
Date
08 Jun 2026
Ownership
See Footnotes
Underlying class
Common Stock
Underlying amount
6,111
Exercise price
$100.64
Footnotes
F3, F4, F6, F7, F8, F9, F13
INCY transaction Derivative

Non-Qualified Stock Options (right to buy)

Award

Transaction value
Shares
+6,111
Change %
Price
$0.000000*
Shares after
6,111
Date
08 Jun 2026
Ownership
See Footnotes
Underlying class
Common Stock
Underlying amount
6,111
Exercise price
$100.64
Footnotes
F3, F4, F6, F7, F8, F9, F13
INCY transaction Derivative

Non-Qualified Stock Options (right to buy)

Award

Transaction value
Shares
+6,111
Change %
Price
$0.000000*
Shares after
6,111
Date
08 Jun 2026
Ownership
See Footnotes
Underlying class
Common Stock
Underlying amount
6,111
Exercise price
$100.64
Footnotes
F3, F4, F6, F7, F8, F9, F13
INCY transaction Derivative

Non-Qualified Stock Options (right to buy)

Award

Transaction value
Shares
+6,111
Change %
Price
$0.000000*
Shares after
6,111
Date
08 Jun 2026
Ownership
See Footnotes
Underlying class
Common Stock
Underlying amount
6,111
Exercise price
$100.64
Footnotes
F3, F4, F6, F7, F8, F9, F13
INCY transaction Derivative

Non-Qualified Stock Options (right to buy)

Award

Transaction value
Shares
+6,111
Change %
Price
$0.000000*
Shares after
6,111
Date
08 Jun 2026
Ownership
See Footnotes
Underlying class
Common Stock
Underlying amount
6,111
Exercise price
$100.64
Footnotes
F3, F4, F6, F7, F8, F9, F13
INCY transaction Derivative

Non-Qualified Stock Options (right to buy)

Award

Transaction value
Shares
+6,111
Change %
Price
$0.000000*
Shares after
6,111
Date
08 Jun 2026
Ownership
See Footnotes
Underlying class
Common Stock
Underlying amount
6,111
Exercise price
$100.64
Footnotes
F3, F4, F6, F7, F8, F9, F13
* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 13 footnotes

Footnote F1

Includes 1,642 restricted stock units (each an "RSU") payable solely in common stock ("Common Stock") of Incyte Corporation (the "Issuer") granted by the Issuer to Julian C. Baker, a managing member of Baker Bros. Advisors (GP) LLC (the "Adviser GP"), on June 8, 2026, pursuant to the Issuer's Amended and Restated 2010 Stock Incentive Plan (the "Incentive Plan"). The RSUs fully vest on the earlier of June 8, 2027, the date of the next annual meeting of stockholders of the Issuer or upon a change in control as defined in the Incentive Plan, subject to Julian C. Baker's continuous service on the board of directors of the Issuer (the "Board") through the vesting date. Julian C. Baker serves on the Board as a representative of 667, L.P. ("667") and Baker Brothers Life Sciences, L.P. ("Life Sciences", and together with 667, the "Funds") and their affiliates and control persons.

Footnote F2

After giving effect to the transactions reported herein and as a result of their ownership interest in (i) Baker Biotech Capital, L.P. and (ii) 667, Julian C. Baker and Felix J. Baker each may be deemed to have an indirect pecuniary interest in Common Stock reported in column 5 of Table I and the non-qualified options to purchase Common Stock of the Issuer ("Stock Options") reported in column 9 of Table II held directly by or held for the benefit of 667, a limited partnership of which the sole general partner is Baker Biotech Capital, L.P., a limited partnership of which the sole general partner is Baker Biotech Capital (GP), LLC, due to their interest in 667 and Baker Biotech Capital, L.P.'s right to receive an allocation of a portion of the profits from 667.

Footnote F3

Baker Bros. Advisors LP (the "Adviser") serves as the investment adviser to the Funds. In connection with the services provided by the Adviser, the Adviser receives an asset-based management fee that does not confer any pecuniary interest in the securities held directly by or held for the benefit of the Funds. The Adviser GP is the Adviser's sole general partner. Julian C. Baker and Felix J. Baker are managing members of the Adviser GP. The Adviser has complete and unlimited discretion and authority with respect to the investment and voting power of the securities held directly by or held for the benefit of the Funds. The general partners of the Funds relinquished to the Adviser all discretion and authority with respect to the investment and voting power of the securities held directly by or held for the benefit of the Funds.

Footnote F4

Julian C. Baker, Felix J. Baker, the Adviser GP and the Adviser disclaim beneficial ownership of the securities held directly by or held for the benefit of the Funds except to the extent of their pecuniary interest therein, and this report shall not be deemed an admission that any of Julian C. Baker, Felix J. Baker, the Adviser GP or the Adviser is a beneficial owner of such securities for purposes of Section 16 or any other purpose.

Footnote F5

Includes beneficial ownership of 15,105 shares of Common Stock previously issued to Julian C. Baker pursuant to the Incentive Plan in lieu of director retainer fees, 14,722 shares of Common Stock received previously from vested RSUs and 245,000 shares of Common Stock received previously from the exercise of 245,000 Stock Options that were issued to Julian C. Baker in his capacity as a director of the Issuer, each of which the Funds are deemed to own a portion.

Footnote F6

Pursuant to the policies of the Adviser, Julian C. Baker does not have a right to any of the Issuer's securities issued as compensation for his service on the Board and the Funds are entitled to an indirect proportionate pecuniary interest in such securities. The Funds each own an indirect proportionate pecuniary interest in such securities. Solely as a result of their ownership interest in (i) the general partners of the Funds and (ii) the Funds, Felix J. Baker and Julian C. Baker may be deemed to have an indirect pecuniary interest in the shares of Common Stock, Stock Options, Common Stock issued upon exercise of Stock Options, RSUs and Common Stock received upon vesting of RSUs (i.e. no direct pecuniary interest) issued as compensation for such Board service.

Footnote F7

Pursuant to the policies of the Adviser, the Adviser has voting and dispositive power over the Stock Options, RSUs and any Common Stock received as a result of the exercise of Stock Options or vesting of RSUs.

Footnote F8

The acquisitions of the RSUs and Stock Options reported on this form represent grants to Julian C. Baker of 1,642 RSUs on Table I and 6,111 Stock Options on Table II. These grants of 1,642 RSUs and 6,111 Stock Options for Julian C. Baker are reported for each of the Funds as each has an indirect pecuniary interest in such securities.

Footnote F9

After giving effect to the transactions reported herein and as a result of their ownership interest in (i) Baker Brothers Life Sciences Capital, L.P. and (ii) Life Sciences, Julian C. Baker and Felix J. Baker each may be deemed to have an indirect pecuniary interest in Common Stock reported in column 5 of Table I and the Stock Options reported in column 9 of Table II held directly by or held for the benefit of Life Sciences, a limited partnership of which the sole general partner is Baker Brothers Life Sciences Capital, L.P., a limited partnership of which the sole general partner is Baker Brothers Life Sciences Capital (GP), LLC, due to their interest in Life Sciences and Baker Brothers Life Sciences Capital, L.P.'s right to receive an allocation of a portion of the profits from Life Sciences.

Footnote F10

Common Stock directly held by Julian C. Baker.

Footnote F11

Common Stock directly held by Felix J. Baker.

Footnote F12

Julian C. Baker and Felix J. Baker may be deemed to have an indirect pecuniary interest in 33,410 shares of Common Stock directly held by FBB Associates. Julian C. Baker and Felix J. Baker are the sole partners of FBB Associates. Julian C. Baker and Felix J. Baker disclaim beneficial ownership of the securities held directly by FBB Associates except to the extent of their pecuniary interest therein, and this report shall not be deemed an admission that Julian C. Baker or Felix J. Baker is a beneficial owner of such securities for purposes of Section 16 or any other purpose.

Footnote F13

Includes 6,111 Stock Options granted by the Issuer to Julian C. Baker on June 8, 2026, pursuant to the Incentive Plan. The Stock Options have a strike price of $100.64 and vest on the earlier of June 8, 2027, the date of the next annual meeting of stockholders of the Issuer or upon a change in control as defined in the Incentive Plan, subject to Julian C. Baker's continuous service on the Board through the vesting date. The Stock Options expire on June 7, 2036.

SEC remarks

Julian C. Baker, a managing member of Baker Bros. Advisors (GP) LLC, the sole general partner of Baker Bros. Advisors LP, is a director of Incyte Corporation (the "Issuer"). By virtue of their representation on the board of directors of the Issuer, for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, the reporting persons other than Julian C. Baker are deemed directors by deputization of the Issuer.

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