Daniel K. Spiegelman - 21 May 2026 Form 4 Insider Report for SPRUCE BIOSCIENCES, INC. (SPRB)

Reporting relationship: Director
Issuer ticker: SPRB
Reported as of: 21 May 2026
Net transaction value: $0
SEC form: 4
Accepted by SEC: 26 May 2026, 16:30:37 UTC
Prior SEC filing: 15 Dec 2025
Next SEC filing: 10 Jun 2026
Source filing: View source filing
Reporting owner signature: /s/ Samir Gharib, Attorney-in-Fact

Key filing fact

Daniel K. Spiegelman filed Form 4 for SPRUCE BIOSCIENCES, INC. (SPRB) on 26 May 2026.

Key facts

This page summarizes Daniel K. Spiegelman's Form 4 filing for SPRUCE BIOSCIENCES, INC. (SPRB).
1 reported transaction and 1 derivative row are listed below.
Accepted by SEC: 26 May 2026, 16:30.

Change

Previous filing in this sequence was filed on 15 Dec 2025.
Current net transaction value: $0.

Research use

This tells you what this filing adds before you inspect full transaction and derivative tables.
You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (1)

CIK 0001238403 Primary reporting owner

SPIEGELMAN DANIEL K

Relationship: Director
Address: C/O SPRUCE BIOSCIENCES, INC., 611 GATEWAY BOULEVARD, SUITE 740, SOUTH SAN FRANCISCO
Signature: /s/ Samir Gharib, Attorney-in-Fact
Signature date: 26 May 2026

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

SPRB transaction Derivative

Stock Option (Right to Buy)

Award

Transaction value
Shares: +1,700
Change %
Price: $0.000000^*
Shares after: 1,700
Date: 21 May 2026
Ownership: Direct
Underlying class: Common Stock
Underlying amount: 1,700
Exercise price: $52.70
Footnotes: F1

^* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Explanation of responses 1 footnote

Footnote F1

The shares vest on the first anniversary of the Grant Date, provided that the Option will in any case be fully vested on the date of Company's 2027 annual stockholder meeting, subject to the Reporting Person's Continuous Service (as defined in the 2020 Equity Incentive Plan (the "Plan")) through such vesting date and will vest in full upon a Change in Control (as defined in the Plan).