SR ONE CAPITAL MANAGEMENT, LLC - 01 May 2026 Form 4 Insider Report for Avalyn Pharma Inc. (AVLN)

Source evidence Original filing metadata and source links for verification. 5 source fields
SEC form
4
Accepted by SEC
01 May 2026, 18:46:03 UTC
Prior SEC filing
29 Apr 2026
Next SEC filing
07 May 2026
Source filing
View source filing
Reporting owner 1 detail
Reporting owner signature
/s/ Sasha Keough, attorney-in-fact for SR One Capital Management, LLC

Key filing fact

SR ONE CAPITAL MANAGEMENT, LLC filed Form 4 for Avalyn Pharma Inc. (AVLN) on 01 May 2026.

Key facts

  • This page summarizes SR ONE CAPITAL MANAGEMENT, LLC's Form 4 filing for Avalyn Pharma Inc. (AVLN).
  • 10 reported transactions and 8 derivative rows are listed below.
  • Accepted by SEC: 01 May 2026, 18:46.

Change

  • Previous filing in this sequence was filed on 29 Apr 2026.
  • Current net transaction value: $0.

Research use

  • This tells you what this filing adds before you inspect full transaction and derivative tables.
  • You can trace every row back to the original SEC filing document.

Evidence

Filed on Form 4

Ownership activity is grounded in SEC Form 4 disclosures.

View source filing

Reporting Owners (2)

CIK 0001853723 Primary reporting owner

SR ONE CAPITAL MANAGEMENT, LLC

Relationship
10%+ Owner
Address
929 MAIN STREET, SUITE 200, REDWOOD CITY
Signature
/s/ Sasha Keough, attorney-in-fact for SR One Capital Management, LLC
Signature date
01 May 2026
CIK 0001595117

George Simeon

Relationship
10%+ Owner
Address
929 MAIN STREET, SUITE 200, REDWOOD CITY
Signature
/s/ Sasha Keough, attorney-in-fact for Simeon George
Signature date
01 May 2026

Reported non-derivative transactions

Shares, units, or other non-derivative securities reported in this filing.

AVLN transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+1,419,298
Change %
Price
Shares after
1,419,298
Date
01 May 2026
Ownership
See Note 2
Footnotes
F1, F2
AVLN transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+1,419,298
Change %
Price
Shares after
1,419,298
Date
01 May 2026
Ownership
See Note 2
Footnotes
F1, F2
AVLN transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+489,486
Change %
+34%
Price
Shares after
1,908,784
Date
01 May 2026
Ownership
See Note 2
Footnotes
F2, F3
AVLN transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+489,486
Change %
+34%
Price
Shares after
1,908,784
Date
01 May 2026
Ownership
See Note 2
Footnotes
F2, F3
AVLN transaction

Common Stock

Purchase

Transaction value
Shares
+277,778
Change %
+15%
Price
$18.00*
Shares after
2,186,562
Date
01 May 2026
Ownership
See Note 2
Footnotes
F2
AVLN transaction

Common Stock

Purchase

Transaction value
Shares
+277,778
Change %
+15%
Price
$18.00*
Shares after
2,186,562
Date
01 May 2026
Ownership
See Note 2
Footnotes
F2
AVLN transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+354,824
Change %
Price
Shares after
354,824
Date
01 May 2026
Ownership
See Note 4
Footnotes
F1, F4
AVLN transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+354,824
Change %
Price
Shares after
354,824
Date
01 May 2026
Ownership
See Note 4
Footnotes
F1, F4
AVLN transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+489,486
Change %
+138%
Price
Shares after
844,310
Date
01 May 2026
Ownership
See Note 4
Footnotes
F3, F4
AVLN transaction

Common Stock

Conversion of derivative security

Transaction value
Shares
+489,486
Change %
+138%
Price
Shares after
844,310
Date
01 May 2026
Ownership
See Note 4
Footnotes
F3, F4
AVLN transaction

Common Stock

Purchase

Transaction value
Shares
+277,777
Change %
+33%
Price
$18.00*
Shares after
1,122,087
Date
01 May 2026
Ownership
See Note 4
Footnotes
F4
AVLN transaction

Common Stock

Purchase

Transaction value
Shares
+277,777
Change %
+33%
Price
$18.00*
Shares after
1,122,087
Date
01 May 2026
Ownership
See Note 4
Footnotes
F4

Reported derivative securities

Options, warrants, convertible securities, or similar derivative positions disclosed in the filing.

AVLN transaction Derivative

Series C-1 Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-27,309,719
Change %
-100%
Price
Shares after
0
Date
01 May 2026
Ownership
See Note 2
Underlying class
Common Stock
Underlying amount
1,419,298
Exercise price
Footnotes
F1, F2
AVLN transaction Derivative

Series C-1 Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-27,309,719
Change %
-100%
Price
Shares after
0
Date
01 May 2026
Ownership
See Note 2
Underlying class
Common Stock
Underlying amount
1,419,298
Exercise price
Footnotes
F1, F2
AVLN transaction Derivative

Series D Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-9,418,561
Change %
-100%
Price
Shares after
0
Date
01 May 2026
Ownership
See Note 2
Underlying class
Common Stock
Underlying amount
489,486
Exercise price
Footnotes
F2, F3
AVLN transaction Derivative

Series D Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-9,418,561
Change %
-100%
Price
Shares after
0
Date
01 May 2026
Ownership
See Note 2
Underlying class
Common Stock
Underlying amount
489,486
Exercise price
Footnotes
F2, F3
AVLN transaction Derivative

Series C-1 Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-6,827,429
Change %
-100%
Price
Shares after
0
Date
01 May 2026
Ownership
See Note 4
Underlying class
Common Stock
Underlying amount
354,824
Exercise price
Footnotes
F1, F4
AVLN transaction Derivative

Series C-1 Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-6,827,429
Change %
-100%
Price
Shares after
0
Date
01 May 2026
Ownership
See Note 4
Underlying class
Common Stock
Underlying amount
354,824
Exercise price
Footnotes
F1, F4
AVLN transaction Derivative

Series D Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-9,418,560
Change %
-100%
Price
Shares after
0
Date
01 May 2026
Ownership
See Note 4
Underlying class
Common Stock
Underlying amount
489,486
Exercise price
Footnotes
F3, F4
AVLN transaction Derivative

Series D Convertible Preferred Stock

Conversion of derivative security

Transaction value
Shares
-9,418,560
Change %
-100%
Price
Shares after
0
Date
01 May 2026
Ownership
See Note 4
Underlying class
Common Stock
Underlying amount
489,486
Exercise price
Footnotes
F3, F4
* marks a reported price that did not pass the local price check.

Additional SEC filing notes

Filing notes and footnotes

Section 16 status

SR ONE CAPITAL MANAGEMENT, LLC is no longer subject to Section 16 filing requirements. Form 4 or Form 5 obligations may still apply in specific circumstances.

Explanation of responses 4 footnotes

Footnote F1

On May 1, 2026, each share of Series C-1 Convertible Preferred Stock (the "Series C-1 Preferred Stock") automatically converted into shares of Common Stock on a one-for-19.2417 basis without payment of further consideration immediately prior to the closing of the Issuer's initial public offering. The Series C-1 Preferred Stock had no expiration date.

Footnote F2

The reported securities are held directly by SR One Capital Fund II Aggregator, LP ("SR One Fund II Aggregator"). SR One Capital Partners II, LP ("SR One Partners II") is the general partner of SR One Fund II, and SR One Capital Management, LLC ("SR One Capital Management") is the general partner of SR One Partners II. Simeon George, M.D. is the managing member of SR One Capital Management. Each of SR One Partners II, SR One Capital Management and Dr. George may be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein.

Footnote F3

On May 1, 2026, each share of Series D Convertible Preferred Stock (the "Series D Preferred Stock") automatically converted into shares of Common Stock on a one-for-19.2417 basis without payment of further consideration immediately prior to the closing of the Issuer's initial public offering. The Series D Preferred Stock had no expiration date.

Footnote F4

The reported securities are held directly by AMZL, LP ("AMZL"). SR One Capital SMA Partners, LP ("SR One SMA Partners") is the general partner of AMZL, and SR One Capital Management is the general partner of SR One SMA Partners. Simeon George, M.D. is the managing member of SR One Capital Management. Each of SR One SMA Partners, SR One Capital Management and Dr. George may be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein.

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