| Name | Relationship | Address | Signature | Signature date | CIK |
|---|---|---|---|---|---|
| Walbert Keli | Director | C/O SPRUCE BIOSCIENCES, INC., 611 GATEWAY BOULEVARD, SUITE 740, SOUTH SAN FRANCISCO | /s/ Samir Gharib, Attorney-in-Fact | 15 Dec 2025 | 0002051489 |
No securities are beneficially owned.
Exhibit List: Exhibit 24 - Power of Attorney